- 1. AMG 531
- [A recombinant protein with megakarypoiesis stimulating activity. AMG 531 mimics endogenous thrombopoietin (TPO), directly binding to and activating the platelet thrombopoietin receptor (TPO-R, Mpl, or CD110 antigen), a cytokine receptor belonging to the hematopoietin receptor superfamily. Activation of TPO-R stimulates the proliferation and differentiation of megakaryocytes, resulting in an increase in the production of blood platelets. ( NCI )] (UMLS (NCI) C1505595) Amgen Megakaryopoiesis Protein 2;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance | |
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