UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AM AMA AMB AMC AMD AME AMF AMG AMH AMI AML AMM AMN AMO AMP AMS AMT AMV AMY
selected terms: 192 page 1 of 2

1. (+)-4-Amino-3-isoxazolidinone
[An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall synthesis by competitively inhibiting two enzymes, L-alanine racemase and D-alanine:D-alanine ligase, thereby impairing peptidoglycan formation necessary for bacterial cell wall synthesis. This agent may be bactericidal or bacteriostatic, depending on its concentration at the infection site and the susceptibility of the organism. In addition, D-cycloserine is an excitatory amino acid and partial agonist at the glycine binding site of the NMDA receptor in the central nervous system (CNS); binding to the central NMDA receptor may result in amelioration of neuropathic pain. ( NCI )] (UMLS (NCI) C0010590) =Amino Acid, Peptide, or Protein; Antibiotic =2-Amino-3-hydroxypropionic Acid;
[AM500] ANTITUBERCULARS =CYCLOSERINE 250 MG;
51. 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
[An imidazoquinolinamine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activates other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans' cells leading to an enhanced activation of T-lymphocytes. Due to its immunostimulatory activity, this agent may potentially be useful as a vaccine adjuvant. ( NCI )] (UMLS (NCI) C0965594) Resiquimod =Organic Chemical; Pharmacologic Substance ;
2. (+)-6-[Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
[An anticancer drug that inhibits the transformation of normal cells to cancer cells. It belongs to the family of drugs called enzyme inhibitors. ( NCI )] (UMLS (NCI) C1176289) Tipifarnib;
=Organic Chemical; Pharmacologic Substance
52. 4-Amino-3-(4-chlorophenyl)-butanoic Acid
[A synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors. It acts at spinal and supraspinal sites, reducing excitatory transmission. (NCI04) ( NCI )] (UMLS (NCI) C0004609) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
3. (+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide Monohydrochloride
[The hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system. ( NCI )] (UMLS (NCI) C0733394) 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol Hydrochloride;
MIDODRINE HYDROCHLORIDE;
MIDODRINE HYDROCHLORIDE PREPARATION;
Midodrine Monohydrochloride =Organic Chemical; Pharmacologic Substance =MIDODRINE;
=MIDODRINE HYDROCHLORIDE 2.5 MG;
MIDODRINE HYDROCHLORIDE 5 MG;
MIDODRINE HYDROCHLORIDE 10 MG
53. 4-Amino-3-[[4'-((2,4-Diaminophenyl)azo)(1,1'-Biphenyl)-4-yl]azo]-5-Hydroxy-6-(Phenylazo)- 2,7-Naphthalenedisulfonic Acid, Disodium Salt
[A Benzidine-based azo dye that is metabolized to free Benzidine in vivo. Direct black 38 is primarily used for the dyeing of textiles, leather and paper. Benzidine and its metabolic derivatives have been detected in the urine of workers exposed to Benzidine-based dyes. Exposure to this dye is strongly associated with the occurrence of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0058437) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
4. (--)-2Amino-3-)3,4-dihydroxyphenyl)propanoic Acid
[naturally occuring form of DOPA and precursor of dopamine; used as an antiparkinsonian agent; unlike dopamine it can be administered orally. ( CSP )] (UMLS (NCI) C0023570) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine ;
=[CN500] ANTIPARKINSON AGENTS;
dihydroxyphenylalanine =LEVODOPA 100 MG;
LEVODOPA 200 MG;
LEVODOPA 250 MG;
Carbidopa 12.5 MG / entacapone 200 MG / Levodopa 50 MG Oral Tablet;
LEVODOPA 150 MG
54. 4-Amino-5-fluoro-2(1H)-pyrimidinone
[fluorinated cytosine analog that is used as an antifungal agent. ( CSP )] (UMLS (NCI) C0016278) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM700] ANTIFUNGALS;
4-Amino-2(1H)-pyrimidinone;
pyrimidine analog;
halocarbon compound =FLUCYTOSINE 250 MG;
FLUCYTOSINE 500 MG;
5. (4-Amino-1-hydroxybutylidene)bisphosphonic Acid
[bone resorption inhibitor. ( CSP )] (UMLS (NCI) C0102118) =Organophosphorus Compound; Pharmacologic Substance ;
=inhibitor/antagonist;
biphosphonate;
[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER;
=ALENDRONATE 70 MG;
ALENDRONATE 35 MG;
ALENDRONATE 10 MG;
ALENDRONATE 5 MG;
ALENDRONATE 40 MG;
55. 4-Amino-7.beta.-D-ribofuranosyl-7H-pyrrolo(2, 3-d)pyrimidine
[antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids; an antineoplastic antimetabolite. ( CSP )] (UMLS (NCI) C0041286) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=antifungal antibiotic;
antineoplastic antibiotics;
antitubercular agent;
ribonucleoside;
nucleoside analog;
6. 1 aminocyclopentyl 1,3 dicarboxylate
[ ] (UMLS (CSP) C0044270) =Organic Chemical; Pharmacologic Substance ;
56. 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide
[A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death. ( NCI )] (UMLS (NCI) C0038745) =Organic Chemical; Pharmacologic Substance ;
=Sulfanilamides;
[AM650] SULFONAMIDE/RELATED ANTIMICROBIALS =SULFISOXAZOLE DIOLAMINE;
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-;
SULFISOXAZOLE DIOLAMINE;
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-;
SULFISOXAZOLE 500 MG;
SULFISOXAZOLE 600 MG;
SULFISOXAZOLE 10 %;
SULFISOXAZOLE 15 %
7. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine
[1-(4-amino-6,7-dimethoxy- 2-quinazolinyl) -4-(2-furoyl) piperazine. ( CSP )] (UMLS (NCI) C0032912) =Organic Chemical; Pharmacologic Substance ;
=antihypertensive agent;
PIPERAZINE;
quinazoline;
[CV150] ALPHA-BLOCKERS/RELATED =Terazosin;
DOXAZOSIN;
PRAZOSIN HYDROCHLORIDE;
PRAZOSIN 5 MG;
PRAZOSIN 1 MG
57. 4-Aminobenzenesulfonamide
[potent antibacterial agent, the first of the sulfonamides discovered. ( CSP )] (UMLS (NCI) C0038702) =Organic Chemical; Antibiotic =Sulfanilamides;
benzenesulfonamide;
antibacterial agent;
[GU300] ANTI-INFECTIVES, VAGINAL =Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-;
SULFANILAMIDE 1.05 GM;
SULFANILAMIDE 15 %;
8. 1-(aminomethyl)cyclohexaneacetic Acid
[A substance that is being studied as a treatment for relieving hot flashes in women with breast cancer. It belongs to the family of drugs called anticonvulsants. ( NCI )] (UMLS (NCI) C0060926) =Organic Chemical; Pharmacologic Substance ;
=Acetic Acids;
[CN400] ANTICONVULSANTS =GABAPENTIN 100 MG;
GABAPENTIN 300 MG;
GABAPENTIN 400 MG;
GABAPENTIN 600 MG;
GABAPENTIN 800 MG;
GABAPENTIN 250 MG/5ML
58. 4-Aminofolic acid
[folic acid derivative used as a rodenticide that has been shown to be teratogenic. ( CSP )] (UMLS (NCI) C0002583) =Organic Chemical; Hazardous or Poisonous Substance
9. 1-Amino-2,4-dibromo-9,10-anthracenedione
[A synthetic, light sensitive, red powder that is insoluble in water and soluble in many organic solvents. It is used as both an intermediate for the production of anthraquinone dyes and as a starting material for the manufacture of vat dyes. The primary route of potential human exposure to 1-amino-2,4-dibromoanthraquinone is dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0626387) =Organic Chemical
59. 5 aminolevulinate synthase
[An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37. ( MSH )] (UMLS (CSP) C0002565) =Amino Acid, Peptide, or Protein; Enzyme ;
10. 1-Amino-2-methyl-9,10-anthracenedione
[A synthetic, red powder that is insoluble in water and soluble in acetone, ethanol, ether, benzene, chloroform and acetic acid. It is used almost exclusively as a dye and dye intermediate for the production of a variety of anthraquinone dyes. The primary routes of potential human exposure to 1-amino-2-methylanthraquinone are inhalation and dermal contact. However, human exposure is limited because this compound is no longer produced in the United States. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0044271) =Organic Chemical
60. 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine Hydroxide, Inner Salt
[physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms; possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. ( CSP )] (UMLS (NCI) C0036002) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =adenosine;
L-Methionine;
high energy compound;
11. 1-amino-3,5-dimethyladamantane Hydrochloride
[The hydrochloride salt form of memantine, a moderate affinity, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine hydrochloride exerts its effect by binding to the cation channels on the NMDA receptor located in the central nervous system, thereby blocking the NMDA receptor and preventing the binding of the excitatory amino acid glutamate. This results in a reduction of abnormal excitement in the brain, which is often seen in Alzheimer's disease. Memantine hydrochloride also acts as an antagonist at the 5HT 3 receptor and the nicotinic receptor. ( NCI )] (UMLS (NCI) C0771988) Ebixia;
MEMANTINE HYDROCHLORIDE =Organic Chemical; Pharmacologic Substance ;
61. 5-Amino-2-hydroxybenzoic Acid
[An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04) ( NCI )] (UMLS (NCI) C0127615) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=Aminosalicylic Acids;
[GA900] GASTRIC MEDICATIONS, OTHER;
[RS100] ANTI-INFLAMMATORIES, RECTAL;
=MESALAMINE 250 MG;
MESALAMINE 500 MG;
MESALAMINE 400 MG;
MESALAMINE 4 GM/60ML
12. 1-Amino-6,17-dihydroxy-7,10,18,21-tetraoxo-27-(n-acetylhydroxylamino)-6,11,17,22-tetraazaheptaeicosane
[natural product isolated from Streptomyces pilosus; it forms iron complexes and is used as a chelating agent, particularly in the mesylate form. ( CSP )] (UMLS (NCI) C0011145) =Organic Chemical; Biologically Active Substance; Indicator, Reagent, or Diagnostic Aid =chelating agent;
Hydroxamic Acids;
hydroxamate;
[AD300] HEAVY METAL ANTAGONISTS =DEFEROXAMINE MESYLATE;
62. 5-Amino-6-(70-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic Acid
[An aminoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces flocculus. Streptonigrin complexes with DNA and topoisomerase II, resulting in DNA cleavage and inhibition of DNA replication and RNA synthesis. This agent also acts as a reverse transcriptase inhibitor and causes free radical-mediated cellular damage. (NCI04) ( NCI )] (UMLS (NCI) C0038427) =Organic Chemical; Antibiotic ;
13. 1-Aminocyclopentane
[A synthetic amino acid derivative of cyclopentanecarboxylic acid, Cycloleucine displays immunosuppressive, antineoplastic, and cytostatic properties. Believed to act in vivo as a valine antagonist and an NMDA receptor antagonist acting at the glycine site, Cycloleucine is a competitive inhibitor of many enzymes, such as methionine adenosyltransferase (S-adenosylmethionine biosynthesis). Toxicity is correlated with a block of nucleic acid methylation; cell cycle progression; and DNA, RNA and protein biosynthesis. (NCI04) ( NCI )] (UMLS (NCI) C0010575) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
63. 6 aminonicotinamide
[A synthetic analogue and nicotinamide antagonist with cytotoxic properties, 6-Aminonicotinamide forms an abnormal NAD (ubiquitous metabolic pathway coenzyme) analog that inhibits NAD-dependent enzyme activity associated with ATP production. 6-Aminonicotinamide impairs cartilage formation, may have teratogenic effects, and enhances the effect of radiation and cisplatin treatment (formation of platinum-DNA complexes). (NCI04) ( NCI )] (UMLS (CSP) C0000610) =Organic Chemical; Pharmacologic Substance; Vitamin; Hazardous or Poisonous Substance
14. 16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure
[A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect. ( NCI )] (UMLS (NCI) C0027444) =Organic Chemical; Antibiotic =macrolide antibiotic;
[OP202] ANTIFUNGALS, TOPICAL OPHTHALMIC =NATAMYCIN 5 %WV;
64. 6-Aminocaproic Acid
[A synthetic lysine derivative with antifibrinolytic activity. Aminocaproic acid competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots as well as fibrinogen and other plasma proteins including the procoagulant factors V and VIII. Aminocaproic acid competitively reduces the conversion of plasminogen to plasmin by plasminogen activators. It directly inhibits proteolytic activity of plasmin, but higher doses are required than are needed to reduce plasmin formation. Aminocaproic acid is used in the treatment of hemorrhage and prophylactically against hemorrhage, including hyperfibrinolysis-induced hemorrhage and postsurgical hemorrhage. ( NCI )] (UMLS (NCI) C0000608) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
15. 2 amino 4 phosphonobutyrate
[ ] (UMLS (CSP) C0206979) =Organic Chemical; Pharmacologic Substance ;
65. 8-Aminoisoindolo(1,2-b)quinazolin-12(10H)-one
[A water insoluble heterocyclic amide with potential antineoplastic activity. Batracylin appears to intercalate into DNA and interferes with topoisomerase II activity, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. The acetylated form of batracylin is highly toxic and capable of inducing unscheduled DNA synthesis. This agent should, therefore, only be administered in patients with a slow acetylator NAT-2 genotype. ( NCI )] (UMLS (NCI) C0053006) =Organic Chemical; Pharmacologic Substance
16. 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium Chloride
[slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors. ( CSP )] (UMLS (NCI) C0006945) =Organic Chemical; Pharmacologic Substance =choline;
cholinergic agent;
[OP102] MIOTICS, TOPICAL OPHTHALMIC;
[OP109] ANTIGLAUCOMA, OTHER =CARBACHOL 0.75 %WV;
CARBACHOL 1.5 %;
CARBACHOL 2.25 %;
CARBACHOL 3 %;
CARBACHOL 0.01 %
66. 9-amino-20(S)-camptothecin
(UMLS (NCI) C0950849) 9-Amino-20-(S)-camptothecin =Organic Chemical; Pharmacologic Substance
17. 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
(UMLS (NCI) C0380453) =Organic Chemical; Pharmacologic Substance ;
67. A-Microtubule
(UMLS (NCI) C1510674) =Cell Component ;
18. 2-Amino 6MP
[thioguanine is USP. ( CSP )] (UMLS (NCI) C0039902) =Organic Chemical; Pharmacologic Substance ;
=1,7-Dihydro-6H-purine-6-thione;
[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
purine;
guanine analog;
=THIOGUANINE 40 MG
68. Amicar
(UMLS (NCI) C0702045) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
19. 2-Amino, 6-Methoxypurine Arabinoside
[An arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0907349) 2-Amino-6-methoxypurine arabinoside;
2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine;
NELARABINE;
Nelarabine Intravenous Injection =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
69. amidation
[ ] (UMLS (CSP) C0678615) =Natural Phenomenon or Process
20. 2-Amino-1,3-Dihydroxyoctadecane
[A saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), L-threo-dihydrosphingosine competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41910&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41910&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1568" NCI Thesaurus) ( PDQ )] (UMLS (NCI) C0074987) =Lipid; Pharmacologic Substance ;
70. amidation/deamidation
[addition of or hydrolytic removal of an amide group. ( CSP )] (UMLS (CSP) C0872015) =Phenomenon or Process ;
=chemical reaction;
21. 2-Amino-1,7-dihydro-6H-purin-6-one
[2-amino-6-hydroxypurine; one of the 5 major bases (with adenine, thymine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0018321) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance =2-Aminopurine;
Hypoxanthines;
nucleobase;
=2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
71. amide
[organic compound derived from ammonia by substituting an acyl radical for hydrogen, or from an acid by replacing the OH group by NH2. ( CSP )] (UMLS (CSP) C0002482) =Organic Chemical ;
22. 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
[9-(2-hydroxyethoxymethyl) guanine; acts against herpesviruses by inhibiting the viral DNA polymerase. ( CSP )] (UMLS (NCI) C0001367) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
72. amidine
[monovalent radical or any compound containing -C(NH)-NH2. ( CSP )] (UMLS (CSP) C0002483) =Organic Chemical ;
23. 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one
[9-(1,3-dihydroxy-2-propoxy)methylguanine; acyclovir analog which inhibits DNA replication of CMV and therefore has efficacy against AIDS-related oculopathy. ( CSP )] (UMLS (NCI) C0017066) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one;
[AM800] ANTIVIRALS;
2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one;
[OP203] ANTIVIRALS, TOPICAL OPHTHALMIC;
nucleoside analog;
=2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one;
DHPG sodium;
GANCICLOVIR 500 MG;
GANCICLOVIR 4.5 MG;
73. amidine lyase
[These enzymes catalyze the elimination of ammonia from amidines with the formation of a double bond. EC 4.3.2. ( MSH )] (UMLS (CSP) C0524943) =Amino Acid, Peptide, or Protein; Enzyme ;
=carbon nitrogen lyase;
24. 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine
[A synthetic, gray-white crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045811) =Organic Chemical; Hazardous or Poisonous Substance ;
74. amidinohydrolase
[ ] (UMLS (CSP) C0002488) =Amino Acid, Peptide, or Protein; Enzyme
25. 2-Amino-3,4-Dimethylimidazole[4,5-f]quinoline
[A synthetic, yellow-green crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). 2-Amino-3-methylimidazo[4,5-f]quinoline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045819) =Organic Chemical; Hazardous or Poisonous Substance ;
75. amidinotransferase
[Enzymes of a subclass of TRANSFERASES that catalyze the transfer of an amidino group from donor to acceptor. EC 2.1.4. ( MSH )] (UMLS (CSP) C0002484) =Amino Acid, Peptide, or Protein; Enzyme
26. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline
[A synthetic, pale orange to brown crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045822) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
76. amidophosphoribosyltransferase
[The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4. (from Gene) ( NCI )] (UMLS (CSP) C0002492) =Amino Acid, Peptide, or Protein; Enzyme
27. 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic Acid
[precursor of serotonin used as antiepileptic and antidepressant. ( CSP )] (UMLS (NCI) C0000578) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
77. Amies transport medium
(UMLS (HL7) C1550050) =Biomedical or Dental Material ;
=Additive/Preservative;
28. 2-Amino-3-hydroxypropionic Acid
[naturally occurring nonessential aminoacid, chemical name 2-amino-3-hydroxypropionic acid; it may be synthesized from glycine or threonine and is involved in the biosynthesis of purines, pyrimidines, and other amino acids. ( CSP )] (UMLS (NCI) C0036720) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =Amino Acids, Neutral;
hydroxyaminoacid;
primary aminoacid;
Inactive Ingredient Preparations;
Unclassified Ingredient Preparations;
=(+)-4-Amino-3-isoxazolidinone;
SERINE 0.33 GM;
SERINE 0.5 GM;
SERINE 1.86 MG/ML;
SERINE 147 MG/100ML;
SERINE 150 MG/100ML;
SERINE 180 MG;
SERINE 2.21 MG/ML;
SERINE 2.25 MG/ML;
SERINE 2.65 MG/ML;
SERINE 20 MG;
SERINE 210 MG/100ML;
SERINE 230 MG/100ML;
SERINE 3 MG/ML;
SERINE 3.7 MG/ML;
SERINE 3.71 MG/ML;
SERINE 300 MG;
SERINE 347 MG/100ML;
SERINE 370 MG;
SERINE 4.5 MG/ML;
SERINE 4.95 MG/ML;
SERINE 420 MG/100ML;
SERINE 5 MG;
SERINE 5.3 MG/ML;
SERINE 5.92 MG/ML;
SERINE 500 MG;
SERINE 500 MG/100ML;
SERINE 56 MG/GM;
SERINE 590 MG/100ML;
SERINE 795 MG/100ML
78. Amies transport medium
[Sodium Chloride 3.0g, Potassium Chloride 0.2g, Calcium Chloride 0.1g, Magnesium Chloride 0.1g, Monopotassium Phosphate 0.2g, Disodium Phosphate 1.15g, Sodium Thiogly collate 1.0g, Distilled Water 1 liter ( HL7V3.0 )] (UMLS (HL7) C1561454) =Intellectual Product =MaterialEntityAdditive;
29. 2-Amino-3-methylimidazo[4,5-f]quinoline
[A synthetic, light tan crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3-methylimidazo[4,5-f]quinoline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). 2-Amino-3-methylimidazo[4,5-f]quinoline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C1312059) 3-Methyl-3H-imidazo[4,5-f]quinolin-2-amine;
IQ =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
79. AMIFOSTINE
[A drug used as a chemoprotective drug to control some of the side effects of chemotherapy and radiation therapy. ( NCI )] (UMLS (NCI) C0015020) =Organophosphorus Compound; Pharmacologic Substance ;
=Organothiophosphorus Compounds;
Protective Agent =AMIFOSTINE 500 MG
30. 2-Amino-4-(S-butylsulfonimidoyl) Butanoic Acid
[used as a thiol depleter and inhibitor of the enzyme gamma glutamylcysteine synthase. ( CSP )] (UMLS (NCI) C0054252) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hazardous or Poisonous Substance =Amino Acids, Sulfur;
sulfhydryl reagent
80. Amifostine/Azacitidine
(UMLS (NCI) C0879480) =Therapeutic or Preventive Procedure ;
31. 2-Amino-5-(carbamoylamino)pentanoic Acid
[amino acid, C6H13N3O3, originally isolated from watermelon, that is produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver; chemical name L-ornithine, N5-(aminocarbonyl). ( CSP )] (UMLS (NCI) C0008864) =Amino Acid, Peptide, or Protein; Biologically Active Substance =aa;
81. Amifostine/Bleomycin/Cisplatin/Etoposide
(UMLS (NCI) C0796553) BLEO/CDDP/VP-16/WR-2721 =Therapeutic or Preventive Procedure
32. 2-amino-5-bromo-6-phenyl-4-(3H)-pyrimidinone
[An oral immunostimulant that causes the body to produce interferon and other substances. ( NCI )] (UMLS (NCI) C0054150) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
82. Amifostine/Busulfan/Melphalan/Thiotepa
(UMLS (NCI) C0677970) =Therapeutic or Preventive Procedure
33. 2-Amino-5-chlorotoluene
[A yellowish to pinkish colored, synthetic leaflet material. p-Chloro-o-toluidine is used in industry in the manufacture of azo dyes and is used in the production of the pesticide chlordimeform. This substance is a possible mutagen and is reasonably anticipated to be a human carcinogen that may be associated with an increased risk of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0048164) =Organic Chemical; Pharmacologic Substance
83. Amifostine/Carboplatin
(UMLS (NCI) C0280482) =Therapeutic or Preventive Procedure ;
34. 2-Amino-6-(trifluoromethoxy)benzothiazole
[A benzathiozole derivative with neuroprotective property. Although the mechanism of action has not been fully elucidated, riluzole may protect neural tissue by inhibiting glutamate release from presynaptic endings in the central nervous system. The agent also blocks postsynaptic NMDA-kainate-type glutamate receptors and inhibits voltage-dependent sodium channels. The inhibition of glutamatergic neurotransmission results in muscle relaxation and sedative effects. ( NCI )] (UMLS (NCI) C0073379) =Organic Chemical; Pharmacologic Substance ;
=thiazole;
[CN900] CNS MEDICATIONS, OTHER =RILUZOLE 50 MG
84. Amifostine/Carboplatin/Cisplatin
(UMLS (NCI) C0280846) =Therapeutic or Preventive Procedure
35. 2-Amino-9,10-anthracenedione
[A synthetic, red or orange-brown needle-shaped solid that is insoluble in water and soluble in alcohol, acetone, benzene and chloroform. It is used as intermediate for the synthesis of both anthraquinone dyes and pharmaceutical products. When 2-aminoanthraquinone is heated to decomposition, it emits toxic fumes of nitrogen oxides. The primary route of potential human exposure to this chemical is dermal contact. Acute exposure of humans to 2-aminoanthraquinone can cause irritation of the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045870) =Organic Chemical; Hazardous or Poisonous Substance ;
85. Amifostine/Carboplatin/Cyclophosphamide
(UMLS (NCI) C0677805) =Therapeutic or Preventive Procedure
36. 2-Aminonaphthalene
[A synthetic, air-sensitive, colorless crystalline solid that is soluble in hot water, alcohol, ether and many organic solvents. Currently, it is only used in laboratory research. Because the commercial production and use of 2-naphthylamine are banned, the potential for human exposure is low. The general population may be exposed to this chemical through inhalation of emissions from sources where nitrogen-containing organic matter is burned, such as coal furnaces and cigarettes. At greatest risk of occupational exposure to 2-naphthylamine are laboratory technicians and scientists who use it in research. Acute inhalation exposure to high levels of 2-naphthylamine can result in methemoglobinemia, dyspnea, ataxia, hematuria, dysuria and hemorrhagic cystitis. It is known to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000300) =Organic Chemical; Hazardous or Poisonous Substance ;
86. Amifostine/Carboplatin/Cyclophosphamide/Thiotepa
(UMLS (NCI) C0796504) CBDCA/CTX/TSPA/WR-2721;
=Therapeutic or Preventive Procedure ;
37. 2-Aminotoluene
[A synthetic, light sensitive, light yellow liquid that is slightly soluble in water and miscible with carbon tetrachloride, diethyl ether and ethanol. The hydrochloride is a synthetic, light sensitive, white crystalline powder that is soluble in dimethylsulfoxide and ethanol. o-Toluidine and o-toluidine hydrochloride are used primarily as intermediates in the manufacture of dyes and pigments. When heated to decomposition, o-toluidine emits toxic fumes of nitrogen oxides while the hydrochloride also produces hydrochloric acid. Four studies of workers exposed to o-toluidine reported an excess of bladder cancers. o-Toluidine and o-toluidine hydrochloride are reasonably anticipated to be human carcinogens. (NCI05) ( NCI )] (UMLS (NCI) C0046584) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
87. Amifostine/Carboplatin/Epirubicin/Paclitaxel
(UMLS (NCI) C0935734) =Therapeutic or Preventive Procedure
38. 2-[(Aminocarbonyl)oxy]-N,N,N-trimethyl-1-propanaminium Chloride
[A synthetic quaternary ammonium base derivative, parasympathomimetic Bethanechol is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Generally used to increase smooth muscle tone, Bethanechol is used to treat reflux esophagitis and to initiate urination after surgery, in urinary infections, or for enlarged prostate. It may cause hypotension, cardiac rate changes, and bronchial spasms. (NCI04) ( NCI )] (UMLS (NCI) C0106169) =Organic Chemical; Pharmacologic Substance =bethanechol;
=BETHANECHOL CHLORIDE 25 MG;
BETHANECHOL CHLORIDE 10 MG;
BETHANECHOL CHLORIDE 50 MG;
BETHANECHOL CHLORIDE 5 MG;
88. Amifostine/Carboplatin/Etoposide/Ifosfamide
(UMLS (NCI) C0796472) CBDCA/IFF/VP-16/WR-2721 =Therapeutic or Preventive Procedure
39. 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m-ethylthiazolium Chloride, Monohydrochloride
[The hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, thiamine hydrochloride is phosphorylated by thiamine diphosphokinase to form active thiamine pyrophosphate (TPP), also known as cocarboxylase. TPP is an coenzyme for many enzymatic activities involving fatty acid, amino acid and carbohydrate metabolism. ( NCI )] (UMLS (NCI) C0770309) THIAMINE HYDROCHLORIDE;
THIAMINE HYDROCHLORIDE PREPARATION;
Vitamin B1 Hydrochloride =Organic Chemical; Pharmacologic Substance; Vitamin =[VT105] THIAMINE;
=CRITICARE HN LIQUID;
LONALAC POWDER,ORAL;
MERITENE More…
89. Amifostine/Carboplatin/Filgrastim/Paclitaxel
(UMLS (NCI) C0678043) =Therapeutic or Preventive Procedure ;
40. 3-(Aminocarbonyl)-O4-deacetyl-3-de-(methoxycarbonyl)vincaleukoblastine
[An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. ( NCI )] (UMLS (NCI) C0042682) =Organic Chemical; Pharmacologic Substance ;
90. Amifostine/Carboplatin/Fluorouracil/Paclitaxel
(UMLS (NCI) C1134464) =Therapeutic or Preventive Procedure
41. 3-(Aminomethyl)-5-methyl-hexanoic Acid
[A 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic and analgesic activities. Pregabalin selectively binds to alpha2delta (A2D) subunit of the presynaptic voltage-gated calcium channels located in the central nervous system (CNS). Binding of A2D subunits prevent calcium influxes and the subsequent calcium-dependent releases of various neurotransmitters from presynaptic nerve terminals in hyperexcited neurons, including glutamate, norepinephrine, serotonin, dopamine, and substance P. This leads to an inhibition of synaptic transmission and reduces neuronal excitability. Pregabalin does not bind directly to GABA-A, GABA-B receptors and does not alter GABA uptake or degradation. ( NCI )] (UMLS (NCI) C0657912) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
91. Amifostine/Carboplatin/Paclitaxel
(UMLS (NCI) C0677736) =Therapeutic or Preventive Procedure ;
42. 3-Amino-1,2,4-benzotriazine-1,4-dioxide
[antineoplastic, radiation sensitizing agent; 3-amino1,2,4-benzotriazine 1,4-dioxide. ( CSP )] (UMLS (NCI) C0208407) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Radiation Sensitizers;
triazine;
92. Amifostine/Carmustine/Cyclophosphamide/Cytarabine/Etoposide
(UMLS (NCI) C0796503) ARA-C/BCNU/CTX/VP-16/WR-2721;
=Therapeutic or Preventive Procedure ;
43. 3-Amino-1-[4-(2 amino-1H-imidazolyl]-propanol, 2HCl
[A compound isolated from the marine sponge Pseudaxinyssa cantharella exhibiting anti-tumor activity. Studies indicate girodazole acts during the elongation/termination steps of protein synthesis, resulting in protein synthesis inhibition. (NCI) ( NCI )] (UMLS (NCI) C0119196) =Organic Chemical; Pharmacologic Substance
93. Amifostine/Ciprofloxacin/Dexamethasone/Pentoxifylline
(UMLS (NCI) C0677760) =Therapeutic or Preventive Procedure
44. 3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone
[3-aminopyridine-2-carboxaldehyde thiosemicarbazone. A substance that is being studied as an anticancer drug. It belongs to the family of drugs called ribonucleotide reductase inhibitors. ( NCI )] (UMLS (NCI) C0210403) =Organic Chemical; Pharmacologic Substance ;
94. Amifostine/Ciprofloxacin/Pentoxifylline
(UMLS (NCI) C0677759) =Therapeutic or Preventive Procedure
45. 4 aminosalicylic acid
[antitubercular agent often administered in association with isoniazid. ( CSP )] (UMLS (CSP) C0030125) =Organic Chemical; Pharmacologic Substance ;
=antitubercular agent;
salicylate
95. Amifostine/Cisplatin
(UMLS (NCI) C0280662) =Therapeutic or Preventive Procedure
46. 4'-Amino-6-hydroxyflavone
[A compound that inhibits the Protein-Tyrosine Kinase Activity of p56lck. ( NCI )] (UMLS (NCI) C0644340) =Organic Chemical; Pharmacologic Substance
96. Amifostine/Cisplatin/Cyclophosphamide/Etoposide
(UMLS (NCI) C0678020) =Therapeutic or Preventive Procedure
47. 4-(Aminomethyl)benzenesulfonamide Monoacetate
[The acetate salt form of mafenide, a synthetic sulfonamide analog of para-aminobenzoic acid (PABA) with topical anti-infective activity. Mafenide acetate competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, thereby interferes with normal folic acid metabolism. As a result de novo synthesis of pyrimidines, which requires folate metabolites, is impeded and subsequently DNA synthesis is affected. Mafenide acetate is bacteriostatic against many gram-negative and gram-positive organisms, including Pseudomonas aeruginosa and certain strains of anaerobes. ( NCI )] (UMLS (NCI) C0024453) =Organic Chemical; Pharmacologic Substance =MAFENIDE;
[DE101] ANTIBACTERIAL, TOPICAL =MAFENIDE ACETATE 8.5 %;
MAFENIDE ACETATE 50 GM;
97. Amifostine/Cisplatin/Cytarabine/Dexamethasone
(UMLS (NCI) C0677980) =Therapeutic or Preventive Procedure
48. 4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
[pyrimidine analog that inhibits DNA methyltransferase, impairing DNA methylation, also an antimetabolite of cytidine, incorporated primarily into RNA; has been used as an antineoplastic agent. ( CSP )] (UMLS (NCI) C0004475) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
98. Amifostine/Cisplatin/Docetaxel
(UMLS (NCI) C0879412) =Therapeutic or Preventive Procedure
49. 4-Amino-10-methylfolic Acid
[folic acid antagonist that acts by inhibiting the synthesis of nucleic acids, thymidylate, and protein; used as an antineoplastic in a wide variety of malignancies, and as an antipsoriatic and antirheumatic. ( CSP )] (UMLS (NCI) C0025677) =Organic Chemical; Pharmacologic Substance ;
=4-Aminofolic acid;
[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
antifolate;
pteridine;
=METHOTREXATE SODIUM
99. Amifostine/Cisplatin/Etoposide
(UMLS (NCI) C0280936) =Therapeutic or Preventive Procedure
50. 4-Amino-2(1H)-pyrimidinone
[2-keto-4-aminopyrimidine, one of the 5 major bases (with adenine, guanine, uracil, and thymine) which are a component of nucleic acids. ( CSP )] (UMLS (NCI) C0010843) =Organic Chemical; Biologically Active Substance =Pyrimidinones;
aminopyrimidine;
nucleobase;
=4-Amino-5-fluoro-2(1H)-pyrimidinone;
1(3-hydroxy-2-phosphonomethoxypropyl) Cytosine
100. Amifostine/Cisplatin/Fluorouracil
(UMLS (NCI) C0677739) =Therapeutic or Preventive Procedure ;

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