- 1. (+ -)-Carbovir
- [An anti-HIV agent that exerts its effects by inhibiting reverse transcriptase. ( NCI )] (UMLS (NCI) C0054727) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 51. CA IN SITU SKIN LIP
- (UMLS (ICD9CM) C0154074) =Neoplastic Process
|
- 2. (+)-Camptothecin
- [alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata; this compound selectively inhibits the nuclear enzyme DNA topoisomerase type I; several semisynthetic analogs of camptothecin have demonstrated antitumor activity. ( CSP )] (UMLS (NCI) C0006812) =Organic Chemical; Pharmacologic Substance =alkaloid;
[AN000] ANTINEOPLASTICS;
indolizine;
=(s)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione;
(+)-(4S)-4,11-diethyl-4-hydroxy-9-[(4-piperidino-piperidino)carbonyloxy]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinol-3,14,(4H,12H)-dione;
(s)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione | - 52. CA IN SITU SKIN NEC
- (UMLS (ICD9CM) C0154082) =Neoplastic Process
|
- 3. (+)-Catechin
- [An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms. ( MSH )] (UMLS (NCI) C0007404) =Organic Chemical; Pharmacologic Substance
| - 53. CA IN SITU SKIN NOS
- [Stage 0: Tis: Carcinoma in situ; N0: No regional lymph node metastasis; M0: No distant metastasis. (Based on AJCC Cancer Staging). - 2002 ( NCI )] (UMLS (ICD9CM) C0154073) =Neoplastic Process
|
- 4. (4-carboxyphthalato)(1,2-diaminocyclohexane)-platinum(II)
- [A second-generation platinum analog with potential antineoplastic activity. Dacplatinum alkylates DNA at the N-7 position of guanine, thereby producing DNA interstrand crosslinks and DNA strand breaks, and inhibiting DNA replication. (NCI04) ( NCI )] (UMLS (NCI) C0054768) =Organic Chemical; Pharmacologic Substance ;
| - 54. CA IN SITU SKIN TRUNK
- (UMLS (ICD9CM) C0154079) =Neoplastic Process
|
- 5. *Catalytic Activity
- (UMLS (HL7) C1547012) =Quantitative Concept =Kind of quantity;
| - 55. CA IN SITU STOMACH
- [Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ: intraepithelial tumor without invasion of the lamina propria. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.) - 2003 ( NCI )] (UMLS (ICD9CM) C0154060) =Neoplastic Process
|
- 6. *Catalytic Concentration
- (UMLS (HL7) C1264648) =Quantitative Concept =Kind of quantity;
| - 56. CA IN SITU TRACHEA
- (UMLS (ICD9CM) C0154070) =Neoplastic Process
|
- 7. *Catalytic Content
- (UMLS (HL7) C1264656) =Quantitative Concept =Kind of quantity;
| - 57. CA IN SITU URINARY NEC
- [ ] (UMLS (ICD9CM) C0154092) =Neoplastic Process
|
- 8. *Catalytic Fraction
- (UMLS (HL7) C1305363) =Functional Concept; ;
=Kind of quantity;
| - 58. CA IN SITU UTERUS NEC
- [ ] (UMLS (ICD9CM) C0154086) =Neoplastic Process
|
- 9. *Catalytic Rate
- (UMLS (HL7) C1264668) =Quantitative Concept =Kind of quantity;
| - 59. Ca-DTPA
- [A drug that protects healthy tissues from the toxic effects of anticancer drugs. ( NCI )] (UMLS (NCI) C0520458) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid =GLYCINE;
Organometallic Compound;
[AD300] HEAVY METAL ANTAGONISTS;
=PENTETATE CALCIUM TRISODIUM 20.6 MG;
PENTETATE CALCIUM TRISODIUM 3 MG;
|
- 10. 1 carbon compound
- [ ] (UMLS (CSP) C0597700) =Organic Chemical ;
=Organic Chemical;
| - 60. CA1/CA2/CA3/CA4 brain regions
- [ ] (UMLS (CSP) C0872337) =Body Part, Organ, or Organ Component ;
|
- 11. 1 carbon transferase
- [ ] (UMLS (CSP) C0597701) =Amino Acid, Peptide, or Protein; Enzyme =EC 2;
=EC 2.1.1;
formininotransferase;
carboxyltransferase/carbamoyltransferase | - 61. CA15-3 Antigen
- [A protein/sugar compound made by some cancer cells. ( NCI )] (UMLS (NCI) C0006611) =Carbohydrate; Immunologic Factor ;
|
- 12. 1-[[5-[[2-(Carboxymethyl)-3-[[decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]methoxy]-4-methoxy-1,4-dioxobutoxy]methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]methoxy]-1,2,3-propanetricarboxylic Acid, 1,2-Dimethyl Ester
- (UMLS (NCI) C0111136) =Organic Chemical
| - 62. CA19-9
- [A carbohydrate antigenic moiety that consists of proteins with sialylated lacto-N-fucopentose II decoration. Cancer antigen 19-9 (CA 19-9) is a protein that exists on the surface of tumor cells, and is cleaved in a process called tumor shedding. Clinically, it is a useful protein marker that is used to follow the course of persons with cancer; and is especially utilized in advanced pancreatic cancers. ( NCI )] (UMLS (NCI) C0006613) =Carbohydrate; Immunologic Factor ;
|
- 13. 14 Carbon
- [An unstable isotope of carbon created when a neutron collides with a nitrogen atom, causing capture of the neutron and release of the proton converting nitrogen to a carbon with fourteen nucleons (6 protons and 8 neutrons). Carbon-14 emits beta particles as it decays and reverts back to nitrogen. ( NCI )] (UMLS (NCI) C0302945) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope ;
| - 63. cA2
- [A monoclonal antibody that blocks the action of a cytokine called tumor necrosis factor alfa. It is being studied in the treatment and prevention of weight loss and loss of appetite in patients with advanced cancer. It belongs to the family of drugs called monoclonal antibodies. ( NCI )] (UMLS (NCI) C0666743) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 14. 3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone
- (UMLS (NCI) C0538429) =Organic Chemical; Pharmacologic Substance
| - 64. Ca2+ transporting ATPase
- [family of ATP-driven, transmembrane molecular pumps which maintain concentration gradients of calcium across a variety of cell membranes, the most notable being sarcoplasmic reticulum term not valid for FY 92. ( CSP )] (UMLS (CSP) C0001476) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 15. 4-carboxyphenyl retinamide
- [A synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Carboxyphenyl retinamide induces cell differentiation and inhibits tumor cell growth and carcinogenesis. This agent may also induce cell cycle arrest in the G1 phase in some cancer cell types. (NCI04) ( NCI )] (UMLS (NCI) C0067533) =Organic Chemical; Pharmacologic Substance
| - 65. Ca42 isotope
- [ ] (UMLS (CSP) C0598042) =Element, Ion, or Isotope ;
|
- 16. 8,8'-(Carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bis-1,3,5-naphthalenetrisulfonic Acid Hexasodium Salt
- [A sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis. ( NCI )] (UMLS (NCI) C0813205) Sodium Suramin;
Suramin Hexasodium;
Suramin sodium =Organic Chemical; Pharmacologic Substance ;
| - 66. Ca44 isotope
- [ ] (UMLS (CSP) C0598043) =Element, Ion, or Isotope ;
|
- 17. 908
- [The calcium salt form of fosamprenavir, prodrug of amprenavir, and a human immunodeficiency virus (HIV) protease inhibitor with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine. Then amprenavir binds to the active site of HIV-1 protease, thereby preventing the proteolytic cleavage of viral Gag-Pol polypeptide into individual functional proteins, thereby leading to the formation of immature non-infectious viral particles. ( NCI )] (UMLS (NCI) C1321660) Fosamprenavir Calcium =Organophosphorus Compound; Pharmacologic Substance
| - 67. Ca45 isotope
- [ ] (UMLS (CSP) C0303383) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope ;
|
- 18. c abl
- [ ] (UMLS (CSP) C0079050) =Gene or Genome
| - 68. Ca46 isotope
- [ ] (UMLS (CSP) C0598044) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope
|
- 19. C.A.T. SCAN OF ABDOMEN
- [ ] (UMLS (ICD9CM) C0412620) =Diagnostic Procedure
| - 69. Ca47 isotope
- [ ] (UMLS (CSP) C0303384) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope ;
|
- 20. C.A.T. SCAN OF HEAD
- (UMLS (ICD9CM) C0202691) =Diagnostic Procedure
| - 70. CA4P
- [An anticancer drug that reduces the blood supply to tumors; it is a tubulin-binding agent. ( NCI )] (UMLS (NCI) C0796467) Combretastatin A4 Phosphate;
Combretastatin A4 Prodrug;
=Organic Chemical; Pharmacologic Substance ;
|
- 21. C.A.T. SCAN OF KIDNEY
- [ ] (UMLS (ICD9CM) C0412623) =Diagnostic Procedure
| - 71. CA4PD
- (UMLS (NCI) C0962508) Combretastatin A4 Disodium Phosphate;
=Organic Chemical; Pharmacologic Substance ;
|
- 22. C.A.T. SCAN OF THORAX
- [ ] (UMLS (ICD9CM) C0202823) =Diagnostic Procedure
| - 72. CAAF1
- [Expressed in monocytes and lymphocytes by human S100A12 Gene (S100 Family), 91-aa 10-kDa (precursor) homodimeric S100 Calcium Binding Protein A12, containing 2 EF-hand calcium-binding motifs, is involved in regulatory effects on cytoskeletal components and in calcium-dependent signal transduction pathways. (NCI) ( NCI )] (UMLS (NCI) C0389073) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 23. C5a
- [Smaller fragment formed when C5 convertase splits C5 into C5a and C5b. C5a is a 74-amino acid peptide that includes a carboxy-terminal arginine crucial for its spasmogenic activity and a carbohydrate moiety. Initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5a is the most potent anaphylatoxin, mediating immediate hypersensitivity. C5a is also chemotactic for neutrophils and monocytes. ( NCI )] (UMLS (NCI) C0009521) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 73. Cabazon Band of Cahuilla Mission Indians of the Ca
- (UMLS (HL7) C1554243) =Population Group =NativeEntityContiguous;
|
- 24. CA
- [A state on the western coast of the United States. Its capital is Sacramento. ( NCI )] (UMLS (NCI) C0006754) =Geographic Area ;
◊ [North American country north of the United States of America; capital city is Ottawa. ( CSP )] (UMLS (NCI) C0006823) Geographic Area ; North America; RealmOfUse ◊ [A term for diseases in which abnormal cells divide without control. Cancer cells can invade nearby tissues and can spread through the bloodstream and lymphatic system to other parts of the body. ( NCI )] (UMLS (NCI) C0006826) Neoplastic Process ; Disease; multiple primary neoplasia; environment related neoplasm/cancer; Detectable Residual Disease; Childhood Cancer; preneoplastic state; host neoplasm interaction; psychological aspect of cancer; neoplasm/cancer site; neoplasm/cancer type; AIDS related neoplasm; hormone related cancer | - 74. cabbage
- [ ] (UMLS (CSP) C0006619) =Food
|
- 25. CA
- [A quantitative measurement of the amount of calcium present in a sample. ( NCI )] (UMLS (NCI) C0201925) =Laboratory Procedure
| - 75. Cable
- [An external limb prosthetic component is a device intended for medical purposes that, when put together with other appropriate components, constitutes a total prosthesis. Examples of external limb prosthetic components include the following: Ankle, foot, hip, knee, and socket components; mechanical or powered hand, hook, wrist unit, elbow joint, and shoulder joint components; and cable and prosthesis suction valves. ( SPN )] (UMLS (NCI) C0492124) =Medical Device
|
- 26. CA 125
- [A substance sometimes found in an increased amount in the blood, other body fluids, or tissues and that may suggest the presence of some types of cancer. ( NCI )] (UMLS (NCI) C0006610) =Carbohydrate; Immunologic Factor ;
| - 76. CAC
- (UMLS (NCI) C0279290) =Therapeutic or Preventive Procedure ;
|
- 27. CA IN SITU BOWEL NEC/NOS
- (UMLS (ICD9CM) C0154065) =Neoplastic Process
| - 77. cachectin
- [serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes; has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants; shares two receptors with tumor necrosis factor beta. ( CSP )] (UMLS (CSP) C1456820) TNF;
TNF alpha;
TNFA;
TNF-Alpha;
Tumor Necrosis Factor;
Tumor Necrosis Factor Alpha;
Tumor Necrosis Factor-Alpha;
Tumor Necrosis Factor-alpha (macrophage-derived) =Amino Acid, Peptide, or Protein; Immunologic Factor =monokine;
|
- 28. CA IN SITU BRONCHUS/LUNG
- (UMLS (ICD9CM) C0154071) =Neoplastic Process
| - 78. cachexia
- [state of general ill health characterized by malnutrition, weakness, and emaciation; occurs during the course of a chronic disease. ( CSP )] (UMLS (CSP) C0006625) =Sign or Symptom =Emaciation;
Clinical Finding |
- 29. CA IN SITU CERVIX UTERI
- [Stage 0 includes: (Tis, N0, M0). Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.) - 2003 ( NCI )] (UMLS (ICD9CM) C0851140) Carcinoma in situ of Cervix;
Carcinoma in situ of Cervix Uteri;
Carcinoma in situ of the Cervix;
Carcinoma in situ of the Cervix Uteri;
Carcinoma in situ of the Uterine Cervix;
Carcinoma in situ of Uterine Cervix;
Cervical cancer stage 0;
Cervical Carcinoma in situ;
Cervical Intraepithelial Neoplasia Grade 3;
Cervical Severe More… | - 79. Cachil DeHe Band of Wintun Indians of the Colusa I
- (UMLS (HL7) C1554244) =Population Group =NativeEntityContiguous;
|
- 30. CA IN SITU COLON
- [Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ: intraepithelial or invasion of lamina propria. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.)-2003 ( NCI )] (UMLS (ICD9CM) C0154061) =Neoplastic Process
| - 80. Caco-2 Cell
- [Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation. ( MSH )] (UMLS (NCI) C0282560) =Cell ;
|
- 31. CA IN SITU ESOPHAGUS
- [Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.) - 2003 ( NCI )] (UMLS (ICD9CM) C0154059) =Neoplastic Process
| - 81. CACO3/VIT-D
- (UMLS (NCI) C0677766) =Therapeutic or Preventive Procedure
|
- 32. CA IN SITU EYE
- [ ] (UMLS (ICD9CM) C0154094) =Neoplastic Process
| - 82. CAD
- [computer hardware, database, software or program used by medical and health personnel to assist in patient diagnostic testing; for recommended schedules of therapy use COMPUTER ASSISTED PATIENT CARE. ( CSP )] (UMLS (NCI) C0011905) =Diagnostic Procedure =Diagnosed;
computer program;
biomedical automation;
|
- 33. CA IN SITU EYELID
- [ ] (UMLS (ICD9CM) C1112527) Carcinoma in situ of eyelid, including canthus =Neoplastic Process
| - 83. CAD
- (UMLS (NCI) C0170509) =Therapeutic or Preventive Procedure
|
- 34. CA IN SITU FEM GEN NEC
- [ ] (UMLS (ICD9CM) C1955739) Carcinoma in situ of other female genital organ;
=Neoplastic Process | - 84. CAD
- [This gene is involved in nucleotide biosynthesis. ( NCI )] (UMLS (NCI) C1413078) CAD Gene;
Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase Gene =Gene or Genome |
- 35. CA IN SITU FEM GEN NOS
- [ ] (UMLS (ICD9CM) C1955737) Carcinoma in situ of unspecified female genital organ;
=Neoplastic Process | - 85. CAD (coronary artery disease)
- [Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause. ( MSH )] (UMLS (CSP) C1956346) coronary artery disease;
=Disease or Syndrome |
- 36. CA IN SITU GI NEC/NOS
- (UMLS (ICD9CM) C0154067) =Neoplastic Process
| - 86. cadaver
- [A dead body, usually a human body. ( MSH )] (UMLS (CSP) C0006629) =Anatomical Structure =Dead;
=Postmortem Changes;
|
- 37. CA IN SITU LARYNX
- [Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.)-2003 ( NCI )] (UMLS (ICD9CM) C0154069) =Neoplastic Process
| - 87. Cadaver donor
- (UMLS (HL7) C1548660) =Idea or Concept =Patient_s Relationship to Insured;
|
- 38. CA IN SITU LIVER/BILIARY
- [ ] (UMLS (ICD9CM) C0496854) =Neoplastic Process
| - 88. Caddo
- (UMLS (HL7) C0574547) =Language =SouthernCaddoan;
|
- 39. CA IN SITU MALE GEN NEC
- [ ] (UMLS (ICD9CM) C0154090) =Neoplastic Process
| - 89. Caddo Indian Tribe of Oklahoma
- (UMLS (HL7) C1554245) =Population Group =NativeEntityContiguous;
|
- 40. CA IN SITU NEC
- (UMLS (ICD9CM) C0007100) =Neoplastic Process ;
| - 90. Caddoan
- (UMLS (HL7) C1698049) =Language ;
=AmericanIndianAlaskaNativeLanguages;
=SouthernCaddoan;
NorthernCaddoan |
- 41. CA IN SITU NOS
- [(kar-sin-O-ma in SYE-too) Cancer that involves only the cells in which it began and that has not spread to neighboring tissues. ( NCI )] (UMLS (ICD9CM) C0007099) =Neoplastic Process ;
=carcinoma;
=Cervical Dysplasia;
PIN | - 91. cadherin
- [family of cell surface glycoproteins, first identified in vertebrates, that mediate calcium dependent, homophilic cell adhesion and thereby control tissue morphogenesis. ( CSP )] (UMLS (CSP) C0006631) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=Adhesion Molecule;
|
- 42. CA IN SITU ORAL CAV/PHAR
- (UMLS (ICD9CM) C0154058) =Neoplastic Process
| - 92. Cadherin 1, Type 1, E-Cadherin (Epithelial) Gene
- [This gene plays a role in cell-cell adhesion and loss of function contributes to the progression of many carcinomas. ( NCI )] (UMLS (NCI) C0694872) =Gene or Genome
|
- 43. CA IN SITU RECTUM
- [Stage 0 includes: (Tis, N0, M0). Tis: Carcinoma in situ: intraepithelial or invasion of the lamina propria. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.)-2003 ( NCI )] (UMLS (ICD9CM) C0154062) =Neoplastic Process
| - 93. Cadherin 13, H-Cadherin (Heart) Gene
- [This gene is a mediator of cell-cell adhesion and a negative regulator of neural growth. ( NCI )] (UMLS (NCI) C1332728) CDH13;
CDH13 Gene;
=Gene or Genome ;
|
- 44. CA IN SITU RESP SYS NEC
- (UMLS (ICD9CM) C0154072) =Neoplastic Process
| - 94. Cadherin 3, Type 1, P-Cadherin (Placental) Gene
- [This gene is involved in the regulation of calcium-dependent cell-cell adhesion. ( NCI )] (UMLS (NCI) C1337110) CDH3;
CDH3 Gene;
=Gene or Genome |
- 45. CA IN SITU RESP SYS NOS
- [ ] (UMLS (ICD9CM) C0348402) =Neoplastic Process
| - 95. Cadherin 5, Type 2, VE-Cadherin (Vascular Epithelium) Gene
- [This gene plays a role in cellular adhesion and endothelial cell cohesion. ( NCI )] (UMLS (NCI) C1332729) CDH5;
CDH5 Gene;
=Gene or Genome ;
|
- 46. CA IN SITU SCALP
- (UMLS (ICD9CM) C0154078) =Neoplastic Process
| - 96. Cadherin EGF LAG Seven-Pass G-Type Receptor 1
- [Cadherin EGF LAG Seven-Pass G-Type Receptor 1, encoded by the human CELSR1 gene, is a G-Protein Coupled Receptor that may have an important role in cell/cell signaling during nervous system formation. It is an integral membrane protein with seven transmembrane domains, multiple cadherin repeats, EGF-like repeats, and laminin A G-type repeats. Two isoforms (1 and 2) may be produced by alternative splicing. The CELSR1 gene is developmentally regulated and neural-specific and the protein plays an unspecified role in early embryogenesis. (From LocusLink, Swiss-Prot, PubMed and NCI) ( NCI )] (UMLS (NCI) C1335562) CELSR1;
Flamingo (Drosophila) Homolog;
Protocadherin Flamingo 2;
=Amino Acid, Peptide, or Protein; Receptor |
- 47. CA IN SITU SKIN ARM
- (UMLS (ICD9CM) C0154080) =Neoplastic Process
| - 97. Cadherin Family Memebr 12
- [Encoded by human RET Gene, Tyrosine-Protein Kinase Receptor RET is a type I membrane protein receptor for Glial Cell Line-Derived Neurotrophic Factor with an extracellular cadherin-like domain and important in neural crest development. Activation of the RET kinase results in autophosphorylation of tyrosine residues critical for signaling. RET mutations are associated with Hirschsprung's disease and Multiple Endocrine Neoplasia, pheochromocytoma, hyperparathyroidism and medullary thyroid cancer. ( NCI )] (UMLS (NCI) C0919475) Glial Cell Line Derived Neurotrophic Factor Receptor Component;
Hydroxyaryl-Protein Kinase;
RET;
RET Gene Product;
RET Protein;
Tyrosine-Protein Kinase Receptor RET;
=Amino Acid, Peptide, or Protein; Enzyme |
- 48. CA IN SITU SKIN EAR
- [ ] (UMLS (ICD9CM) C0347139) =Neoplastic Process
| - 98. Cadherin, EGF LAG Seven-Pass G-Type Receptor 1 (Flamingo Homolog, Drosophila) Gene
- [This gene plays a role in cellular contact-mediated communication and embryonic regulation. ( NCI )] (UMLS (NCI) C1332751) CELSR1;
CELSR1 Gene;
=Gene or Genome ;
|
- 49. CA IN SITU SKIN FACE NEC
- (UMLS (ICD9CM) C0154077) =Neoplastic Process
| - 99. Cadherin-1
- [Encoded by human CDH1 Gene (CDH Family), 882-amino acid 97 kD (precursor) invasion suppressor type I membrane protein E-Cadherin is the main homodimeric Ca(2+)-dependent cell-cell adhesion glycoprotein in non-neural epithelia. Structurally similar to immunoglobulins, E-cadherin contains five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail required for internalization. E-Cadherin acts as ligand for integrin Alpha-E/Beta-7. CDH1 defects cause Familial Gastric Cancer. CDH1 mutations are correlated with breast, colorectal, thyroid, and ovarian cancer. E-cadherin down regulation often correlates with invasive potential and poor prognosis of human carcinomas; it is likely a main event in cancer proliferation, invasion, and metastasis, due to dysfunction of cell-cell adhesion. (from LocusLink, SWISS-PROT, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0042172) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 50. CA IN SITU SKIN LEG
- (UMLS (ICD9CM) C0154081) =Neoplastic Process
| - 100. Cadherin-2
- [Human Neural-cadherin is encoded by the CDH2 gene. The gene product is 906 amino acids and ~100kD in size. This protein plays a role in calcium-dependent cell adhesion. ( NCI )] (UMLS (NCI) C0027215) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
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