- 2. C5a
- [Smaller fragment formed when C5 convertase splits C5 into C5a and C5b. C5a is a 74-amino acid peptide that includes a carboxy-terminal arginine crucial for its spasmogenic activity and a carbohydrate moiety. Initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5a is the most potent anaphylatoxin, mediating immediate hypersensitivity. C5a is also chemotactic for neutrophils and monocytes. ( NCI )] (UMLS (NCI) C0009521) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 4. CAAF1
- [Expressed in monocytes and lymphocytes by human S100A12 Gene (S100 Family), 91-aa 10-kDa (precursor) homodimeric S100 Calcium Binding Protein A12, containing 2 EF-hand calcium-binding motifs, is involved in regulatory effects on cytoskeletal components and in calcium-dependent signal transduction pathways. (NCI) ( NCI )] (UMLS (NCI) C0389073) =Amino Acid, Peptide, or Protein; Biologically Active Substance
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