- 1. CD3
- [T-lymphocyte marker that functions as a molecular bridge holding the T-cell antigen receptor to the cell surface, and coupling antigen- TCR binding to T-cell activation events. ( CSP )] (UMLS (NCI) C0108779) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
=CD antigen;
| - 5. CD34
- [A protein found on the surface of some bone marrow and blood cells. ( NCI )] (UMLS (NCI) C0054953) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
=CD antigen;
|
- 2. CD32
- [ ] (UMLS (CSP) C0054951) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 6. CD34
- [This gene is involved in hematopoiesis; however, a specific physiological function has yet to be identified. ( NCI )] (UMLS (NCI) C1332710) CD34 Antigen Gene;
CD34 Gene;
=Gene or Genome |
- 3. CD32
- [Expressed as 4 alternative isoforms in monocytes, macrophages, polymorphonuclear cells, and natural killer cells (Isoform 1) by human FCGR2C Gene, IgG Fc Receptor IIC is a type I cell surface protein with 2 IgC2 domains and a low affinity receptor for aggregated IgG Fc region. FCGR2C binding to IgG initiates essential effector and regulatory cellular responses against foreign pathogens and soluble antigens that induce phagocytosis of antigen-antibody complexes, removing them from circulation, and modulate B-cell antibody production. FCGR2C contains two cytoplasmic ITAM activator motifs involved in cell activation upon receptor aggregation. Isoform 4 may be soluble. (NCI) ( NCI )] (UMLS (NCI) C0215037) =Amino Acid, Peptide, or Protein; Receptor ;
| - 7. CD36
- [This gene is involved in the regulation of cellular transport and adhesion. ( NCI )] (UMLS (NCI) C1366645) CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor) Gene;
CD36 Gene =Gene or Genome |
- 4. CD32
- [Expressed as 3 alternative isoforms in monocytes, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B cells, platelets, and placental endothelial by human FCGR2B Gene, IgG Fc Receptor IIB is a type I cell surface protein with 2 IgC2 domains and the most broadly distributed low affinity receptor for aggregated IgG Fc region. FCGR2B binding to IgG initiates essential effector and regulatory cellular responses against foreign pathogens and soluble antigens that induce phagocytosis of antigen-antibody complexes, removing them from circulation, and modulate B-cell antibody production. FCGR2B contains a cytoplasmic ITIM motif involved in down modulation of previous cell activation by BCR, TCR or another Fc receptor; phosphorylated ITIM binds to PTPN6/SHP-1 SH2 domain. Chromosome translocation t(1;22)(q22;q11) leads to FCGR2B hyperexpression in a follicular lymphoma. (NCI) ( NCI )] (UMLS (NCI) C1452607) CD32 Antigen;
FCG2;
Fc-Gamma RIIB;
Fc-Gamma-RIIB;
FCGR2;
FCGR2B;
FcRIIB;
IGFR2;
IgG Fc Receptor IIB;
Low Affinity IgG Fc Fragment Receptor IIB;
Low Affinity Immunoglobulin Gamma Fc Region Receptor IIB;
=Amino Acid, Peptide, or Protein; Receptor | |
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