- 1. CD8
- [CD8 Antigen Beta Polypeptide-1 is encoded by the CD8 Antigen Beta Polypeptide-1 gene (CD8B1) located at 2p12 and expressed as alternative membrane-associated cell surface or secreted isoforms in most suppressor and cytotoxic T lymphocytes. CD8 Antigen Beta Polypeptide 1 glycoprotein exhibits significant homology to Ig variable light chains and mediates efficient cell-cell interactions in the immune system, as an alpha/alpha or alpha/beta coreceptor with T-cell receptor. CD8B1 recognizes antigen displayed in an MHC I context by antigen presenting cells. ( NCI )] (UMLS (NCI) C1332717) CD8 Antigen, Beta Polypeptide 1;
CD8B;
CD8B1;
LYT3;
T-Cell Glycoprotein CD8b =Amino Acid, Peptide, or Protein; Immunologic Factor | - 3. CD82
- [This gene plays a role in the regulation of membrane receptor functions. ( NCI )] (UMLS (NCI) C0812444) CD82 Antigen Gene;
CD82 Gene =Gene or Genome ;
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- 2. CD80
- [This gene is involved in the stimulation of T-cells and in immune responses. ( NCI )] (UMLS (NCI) C1366561) CD80 Antigen (CD28 Antigen Ligand 1, B7-1 Antigen) Gene;
CD80 Gene =Gene or Genome | - 4. CD87
- [High affinity cellular receptor for urokinase plasminogen activator (uPA). Plays a role in plasminogen activation by facilitating the conversion of uPA to an enzymatically active form anchored to the cell membrane, where plasminogen activation occurs. Affects tissue remodeling (surface proteolysis, cell adhesion, cell migration), and cancer invasion. ( NCI )] (UMLS (NCI) C0071216) =Amino Acid, Peptide, or Protein; Receptor ;
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