UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
H H+ H1 HA HB HC HD HE HF HG HH HI HK HL HM HN HO HP HQ HR HS HT HU HV HX HY HZ
selected terms: 2,761 page 1 of 28

1. (-)-Hydromorphone
[The hydrogenated ketone of morphine, a semi-synthetic opioid with analgesic effects. Hydromorphone selectively binds the mu-opioid receptor which is linked through G-proteins. Binding stimulates the exchange of guanosine triphosphate (GTP) for guanosine diphosphate (GDP) on the G-protein complex and interacts with and inhibits adenylate cyclase located at the inner surface of the plasma membrane. This leads to a reduction in intracellular cyclic 3',5'-adenosine monophosphate (cAMP). Further, voltage-gated potassium channels are activated, thereby causing hyperpolarization and reducing neuronal excitability. In addition, the opening of voltage-gated calcium channels is inhibited, thereby leading to an inhibition of calcium entry and a reduction in the release of various neurotransmitters, including GABA, vasopressin, somatostatin, insulin and glucagons. ( NCI )] (UMLS (NCI) C0012306) =Organic Chemical; Pharmacologic Substance =[CN101] OPIOID ANALGESICS;
Morphine Derivatives =OXYMORPHONE;
HYDROMORPHONE HYDROCHLORIDE;
HYDROMORPHONE 2 MG
51. 1H-Indole-3-butanoic Acid
(UMLS (NCI) C0063503) =Organic Chemical
2. (.+-.)-Hexestrol
[A synthetic hydrogenated derivative of diethylstilbestrol (DES). Hexestrol exhibits strong affinity for estrogen receptors that are overexpressed in some types of cancers. When conjugated with a neoplastic drug, hexestrol may selectively concentrate the cytotoxic agent in estrogen receptor-rich tumors. This agent may also be mutagenic. (NCI04) ( NCI )] (UMLS (NCI) C0019467) =Organic Chemical; Pharmacologic Substance; Hormone
52. 1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, Monobenzoate
[The benzoate salt form of rizatriptan, a member of the triptan class agents with anti-migraine property. Rizatriptan benzoate selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries, and to 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Rizatriptan benzoate may also relief migraine headaches by inhibition of pro-inflammatory neuropeptide release. ( NCI )] (UMLS (NCI) C0772420) Rizatriptan Benzoate;
RIZATRIPTAN BENZOATE PREPARATION =Organic Chemical; Pharmacologic Substance ;
=RIZATRIPTAN;
=RIZATRIPTAN BENZOATE 10 MG;
RIZATRIPTAN BENZOATE 5 MG
3. (1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene Dipivalate Hydrochloride
[An ester with sympathomimetic activities. Dipivefrin hydrochloride is a prodrug of epinephrine that, due to its greater lipophilicity, allows for better penetration into the anterior chamber. Once inside the eye, dipivefrin hydrochloride is converted by hydrolysis to epinephrine. Epinephrine enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. This leads to a reduction in intraocular pressure. ( NCI )] (UMLS (NCI) C0700488) =Organic Chemical; Pharmacologic Substance =DIPIVEFRIN;
=DIPIVEFRIN HYDROCHLORIDE 0.1 %;
53. 1H-indole-3-methanol
[A substance that is being studied as a cancer prevention drug. It is found in cruciferous vegetables. ( NCI )] (UMLS (NCI) C0063491) =Organic Chemical; Pharmacologic Substance ;
4. (1-Hydroxyethylidene)bisphosphonic Acid
[As a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts. (NCI) ( NCI )] (UMLS (NCI) C0015121) =Organophosphorus Compound; Pharmacologic Substance ;
=biphosphonate;
=EHDP;
Risedronic Acid;
54. 1H-Purin-6-amine
[6-aminopurine; one of the 5 major bases (with guanine, thymine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0001407) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
5. (1H-Indol-3-ylmethyl)carbamodithioic Acid, Methyl Ester
(UMLS (NCI) C0258434) =Organic Chemical; Pharmacologic Substance
55. 1H-Purin-6-amine, 2-fluoro- (9CI)
[A fluorinated heterocyclic 2-ring compound. 2-fluoroadenine is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies. ( NCI )] (UMLS (NCI) C0046110) =Nucleic Acid, Nucleoside, or Nucleotide
6. 1 hour post challenge
(UMLS (HL7) C1547065) =Temporal Concept =Time delay post challenge;
56. 1H-Purine-2,6-diamine
[One of a number of organic compounds that share a similar purine structure and possess antiviral and antitumor properties. 2,6-Diaminopurine nucleosides are versatile synthetic precursors for specific N-6 modifications of antiviral and antitumor agents. (NCI04) ( NCI )] (UMLS (NCI) C0045587) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
7. 1(2H)-Phthalazinone Hydrazone
[direct-acting vasodilator that is used as an antihypertensive. ( CSP )] (UMLS (NCI) C0020223) =Organic Chemical; Pharmacologic Substance =antihypertensive agent;
hydrazine;
Phthalazines;
[CV490] ANTIHYPERTENSIVES, OTHER =HYDRALAZINE HYDROCHLORIDE;
HYDRALAZINE 50 MG
57. 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compound with 1,2-Ethanediamine(2:1)
[drug combination that contains theophylline and ethylenediamine; its most common use is in bronchial asthma, but it has been investigated for several other applications. ( CSP )] (UMLS (NCI) C0002575) =Organic Chemical; Pharmacologic Substance
8. 1(2H)-Phthalazinone, 4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, Monohydrochloride
[The hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. ( NCI )] (UMLS (NCI) C0771004) Azelastine Hydrochloride;
AZELASTINE HYDROCHLORIDE PREPARATION;
W-2979M =Organic Chemical; Pharmacologic Substance =AZELASTINE;
=AZELASTINE HYDROCHLORIDE 0.05 %;
AZELASTINE HYDROCHLORIDE 137 MCG/ACTUAT
58. 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl
[A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema. ( NCI )] (UMLS (NCI) C0013360) =Organic Chemical; Pharmacologic Substance =3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione;
[RE104] BRONCHODILATORS, XANTHINE-DERIVATIVE;
TO BE DELETED INGREDIENT PREPARATIONS;
=DYPHYLLINE 125 MG/ML;
Dyphylline 20 MG/ML;
DYPHYLLINE 200 MG;
DYPHYLLINE 250 MG/ML;
DYPHYLLINE 400 MG;
DYPHYLLINE 100 MG/15ML;
Dyphylline 10.7 MG/ML;
DYPHYLLINE 100 MG
9. 1(2H)-Pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-
[An antimetabolite (pyrimidine analogue) antineoplastic derivative of 5-fluorouracil. (NCI) ( NCI )] (UMLS (NCI) C0044401) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
59. 1H-Pyrazole, 4-methyl-
[A pyrazole with competitive alcohol dehydrogenase inhibitor activity. Fomepizole prevents the metabolism of ethylene glycol and methanol by alcohol dehydrogenase, thereby inhibiting the formation of their toxic metabolites, glycolate and oxalate (from ethylene glycol), and formic acid (from methanol). Fomepizole is indicated for use as an antidote in ethylene glycol and methanol poisoning. (NCI05) ( NCI )] (UMLS (NCI) C0048504) =Organic Chemical; Pharmacologic Substance =Pyrazole Compound;
1H-Pyrazole, 4-methyl-;
[AD900] ANTIDOTES/DETERRENTS, OTHER;
=1H-Pyrazole, 4-methyl-;
FOMEPIZOLE 1 GM/ML;
10. 1(3-hydroxy-2-phosphonomethoxypropyl) Cytosine
[1(3-hydroxy-2-phosphonomethoxypropyl) cytosine; potent selective inhibitor of human cytomegalovirus replication; used in CMV retinitis therapy. ( CSP )] (UMLS (NCI) C0286079) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
4-Amino-2(1H)-pyrimidinone;
Organophosphorus Compounds;
cytosine analog =CIDOFOVIR 75 MG/ML
60. 1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2((5-methyl-1H-imidazol-4-yl)methyl)-, Monohydrochloride
[The chloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron hydrochloride blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons. Alosteron hydrochloride affects the regulation of visceral pain, decreases gastrointestinal contraction and motility, and decreases gastrointestinal secretions. This drug is used to treat diarrhea-predominant irritable bowel syndrome in women. (NCI05) ( NCI )] (UMLS (NCI) C0291771) =Organic Chemical; Pharmacologic Substance =alosetron;
11. 1(3H)Isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3,-dioxolo(4,5-g)isoquinolin-5-yl)-hydrochloride
[The orally available hydrochloride salt of the opioid agonist noscapine, a phthalideisoquinoline alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential antineoplastic activities. Noscapine binds to tubulin and alters its conformation, resulting in a disruption of the dynamics of microtubule assembly (by increasing the time that microtubules spend idle in a paused state) and, subsequently, the inhibition of mitosis and tumor cell death. Unlike other tubulin inhibitors such as the taxanes and vinca alkaloids, noscapine does not affect microtubule polymerization. ( NCI )] (UMLS (NCI) C1450474) Narcotine hydrochloride;
Noscapine HCl;
Noscapine Hydrochloride;
=Organic Chemical; Pharmacologic Substance ;
61. 2 1/2 hours post challenge
(UMLS (HL7) C1547068) =Temporal Concept =Time delay post challenge;
12. 1,1,1,2,2,2-Hexachloroethane
[A crystalline, colorless, toxic, solid chlorinated hydrocarbon with a camphor-like odor and emits toxic and irritating fumes when heated to decomposition. Hexachloroethane was used as an anthelmintic to treat fascioliasis in cattle and sheep, in refining aluminum alloys, in smoke bombs and pyrotechnic and as a degassing agent and polymer additive. Exposure to this substance irritates the skin and mucous membranes, causes liver damage and acts as a central nervous system depressant. Hexachloroethane is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0062606) =Organic Chemical; Pharmacologic Substance ;
62. 2 hours
(UMLS (HL7) C1292425) =Temporal Concept ;
=Duration categories;
13. 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
[A fluorinated isopropyl ether with general anesthetic property. Although the mechanism of action has not been fully elucidated, sevoflurane may act by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, and/or alter ionic conductance following receptor activation by a neurotransmitter. Sevoflurane may also interact directly with lipid matrix of neuronal membranes, thereby affecting gating properties of ion channels. In addition, this agent may activate gamma-aminobutyric acid (GABA) receptors hyperpolarizing cell membranes. This results in a general anesthetic effect, a decrease in myocardial contractility and mean arterial pressure as well as an increased respiratory rate. ( NCI )] (UMLS (NCI) C0074414) =Organic Chemical; Pharmacologic Substance ;
=Methyl Ethers;
[CN201] ANESTHETICS INHALATION =SEVOFLURANE LIQUID (ML)
63. 2 hours post challenge
(UMLS (HL7) C1547072) =Temporal Concept =Time delay post challenge;
14. 1,1-Hydrazodibenzene
[A colorless, crystalline compound that emits toxic fumes of nitrogen oxides when heated to decomposition. Hydrazobenzene has been used primarily in the dye manufacturing industry as the precursor of the dye intermediate benzidine and is also used as an intermediate in the manufacture of pharmaceuticals. Exposure to this substance irritates the skin, nose, throat and lungs and can eventually lead to liver, kidney and brain damage. Hydrazobenzene is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05) ( NCI )] (UMLS (NCI) C0063069) =Organic Chemical; Hazardous or Poisonous Substance ;
64. 2 hydroxyacid oxidase
[ ] (UMLS (CSP) C0597779) =Amino Acid, Peptide, or Protein; Enzyme
15. 1,4,5,6,7,7-Hexachloro-5-norbornene-2,3-dicarboxylic Acid
[A white, crystalline carcinogenic chlorinated hydrocarbon that emits toxic fumes of hydrochloric acid and other chlorinated compounds when heated to decomposition. Chlorendic acid is used as a reactive flame retardant, chemical intermediate, hardening agent and as an extreme pressure lubricant. Exposure to chlorendic acid causes skin, eye and respiratory tract irritation. Chlorendic acid is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05) ( NCI )] (UMLS (NCI) C0082003) =Organic Chemical; Hazardous or Poisonous Substance ;
65. 2(1H)-pyridinone, 4-hydroxy-1-beta-D-ribofuranosyl
[A synthetic analogue of nucleoside uridine lacking a ring nitrogen in the 3-position. 3-deazauridine inhibits cytidine synthase, thereby reducing intracellular levels of cytidine and deoxycytidine and disrupting DNA and RNA synthesis. This agent may trigger apoptosis and enhance differentiation of neoplastic cells.. (NCI04) ( NCI )] (UMLS (NCI) C0000399) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
16. 1,7-Heptanediyl Ester Sulfamic Acid
[A bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as alkylsulfonate alkylating agents. Hepsulfam forms covalent linkages with nucleophilic centers in DNA, resulting in depurination, base miscoding, strand scission, DNA-DNA and DNA-protein cross-linking, and cytotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0062540) =Organic Chemical; Pharmacologic Substance ;
66. 2(1H)-Pyrimidinone, 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)-
[A drug being studied for use as an anticancer agent. ( NCI )] (UMLS (NCI) C0877874) Troxacitabine;
=Organic Chemical; Pharmacologic Substance ;
17. 1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol
[An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors. ( NCI )] (UMLS (NCI) C0031937) =Organic Chemical; Pharmacologic Substance =Propanolamines;
[CV100] BETA-BLOCKERS/RELATED =PINDOLOL 10 MG;
PINDOLOL 5 MG;
67. 2(1H)-Pyrimidinone, 4-amino-1-[4, 5-dihydroxy- 3-(hydroxymethyl)-2-cyclopenten-1-yl]-
[A synthetic cyclopentenyl antimetabolite analogue of cytidine with antineoplastic activity and antiviral activity. Cyclopentenyl cytosine competitively inhibits cytidine triphosphate (CTP) synthase, thereby depleting cytidine pools and inhibiting DNA synthesis. This agent may also induce differentiation of some tumor cell types. Cyclopentenyl cytosine's antiviral activity is broad-spectrum. (NCI04) ( NCI )] (UMLS (NCI) C0111606) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
18. 1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
[synthetic coumarin anticoagulant. ( CSP )] (UMLS (NCI) C0043031) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =4-Hydroxycoumarins;
[BL100] ANTICOAGULANTS;
2H-1-Benzopyran-2-one;
=Prothromadin;
68. 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-,(2R-cis)-
[A synthetic nucleoside analog of cytosine with activity against human immunodeficiency virus type 1 reverse transcriptase. Emtricitabine is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate. Emtricitabine 5'-triphosphate inhibits the activity of the HIV-1 reverse transcriptase by competing with the natural substrate deoxycytidine 5'-triphosphate. Incorporation of emtricabine 5'-triphosphate into nascent viral DNA results in chain termination. Emtricitabine 5'-triphosphate is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon and mitochondrial DNA polymerase gamma. ( NCI )] (UMLS (NCI) C0909839) EMTRICITABINE;
EMTRICITABINE PREPARATION;
FTC;
=Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =[AM800] ANTIVIRALS;
Unclassified Ingredients =EMTRICITABINE 200 MG;
19. 1-Hexadecanaminium, N-(2-(((4-methoxyphenyl)methyl)-2-pyrimidinylamino)ethyl)-N,N-dimethyl-, Bromide
[A cationic surface-active compound. As an additive to pharmacologic formulations, thonzonium bromide causes dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. ( NCI )] (UMLS (NCI) C0724705) Ammonium, hexadecyl(2-((p-methoxybenzyl)-2-pyrimidinylamino)ethyl)dimethyl-, Bromide(8CI);
Thonzonium Bromide;
THONZONIUM BROMIDE PREPARATION =Organic Chemical; Pharmacologic Substance ;
=THONZONIUM;
=THONZONIUM BROMIDE 0.5 MG/ML
69. 2(1H)-pyrimidinone, tetrahydro-4-hydroxy-1-beta-D-ribofuranosyl-
[A synthetic pyrimidine nucleoside analogue with biomodulating activity. Tetrahydrouridine increases the efficacy of the radiosensitizer cytochlor (5-chloro-2'-deoxycytidine) by inhibiting the enzyme deoxycytidine monophosphate (dCMP) deaminase and preventing the premature deamination of the cytochlor metabolite 5-chloro-2'-deoxycytidine monophosphate (CldCMP) to 5-chloro-2'-deoxyuridine monophosphate (CldUMP); in turn, this increases tumor concentrations of CldUMP which is then further anabolized and incorporated selectively into tumor DNA as CldU (5-chloro-2'-deoxyuridine). (NCI04) ( NCI )] (UMLS (NCI) C0039677) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
20. 1-Hexadecanol
[A synthetic, solid, fatty alcohol and nonionic surfactant. Cetyl alcohol is used as an emulsifying agent in pharmaceutical preparations. ( NCI )] (UMLS (NCI) C0055152) =Organic Chemical; Pharmacologic Substance ;
=Fatty Alcohols;
Inactive Ingredient Preparations =AQUA-A CREAM;
AQUADERM CREAM;
AQUADERM LOTION;
MOISTUREL CREAM,TOP;
MOISTUREL LOTION;
UREA 25% LOTION;
CETAPHIL CREAM;
CETAPHIL LOTION;
SALICYLIC ACID 10% CREAM (GRAMS);
COLLOIDAL OATMEAL 1% LOTION (ML);
ALUMINUM ACETATE 1%/CAMPHOR 3%/MENTHOL 0.5%/PHENOL 1% CREAM,TOP;
BENZOIC ACID 12%/SALICYLIC ACID 6% CREAM,TOP;
CETYL ALCOHOL LIQUID;
EXTRA STRENGTH HAND & NAIL LOTION;
GLYCERIN/PETROLATUM/ZINC OXIDE LOTION;
I.S.P. LOTION;
LOBANA BODY LOTION;
MOISTURE DERM LOTION;
MOISTURIZING LOTION;
MONOBASE CREAM,TOP;
NUSOAP CLEANSING LIQUID;
NUSOAP SOAP;
OCTYL METHOXYCINNAMATE/OCTYL SALICYLATE/OXYBENZONE SPF-15 LOTION;
OXICONAZOLE 1% LOTION;
OXYBENZONE 2%/PADIMATE O 5% LOTION;
OXYBENZONE 3%/PADIMATE O 8% LOTION;
OXYBENZONE/PADIMATE O LOTION;
RAYNOX CREAM;
SPECTRO-JEL TOP;
SULFUR 5%/SULFURATED POTASH/ZINC OXIDE 10% CREAM,TOP;
THERI-CARE LOTION;
UNDECYLENIC ACID 5%/ZINC UNDECYLENATE 20% CREAM,TOP;
VASELINE INTENSIVE CARE LOTION;
terbinafine 10 MG/ML Topical Cream;
KERI FACIAL CLEANSER LIQUID,TOP;
POVIDONE IODINE 5% CREAM,TOP;
CETYL ALCOHOL/COLFOSCERIL PALMITATE/TYLOXAPOL SUSP,ITRC;
CETYL ALCOHOL 1 %
70. 2(1H)-Quinolinone, 7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydro-
[A quinoline derivate and atypical anti-psychotic agent. Aripiprazole has partial agonistic activity at dopamine D2 receptors and serotonin 5-HT1A receptors, as well as potent antagonistic activity on serotonin 5-HT2A receptors. This drug stabilizes dopamine and serotonin activity in the limbic and cortical system. Aripiprazole is used in managing symptoms of schizophrenia and of acute manic and mixed episodes associated with bipolar I disorders. ( NCI )] (UMLS (NCI) C0299792) =Organic Chemical; Pharmacologic Substance =[CN709] ANTIPSYCHOTICS, OTHER;
Unclassified Ingredients =ARIPIPRAZOLE 15 MG;
ARIPIPRAZOLE 10 MG;
ARIPIPRAZOLE 30 MG;
ARIPIPRAZOLE 20 MG;
ARIPIPRAZOLE 5 MG
21. 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-,(E)-2-butenedioate(1:1)
[The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils. ( NCI )] (UMLS (NCI) C0043443) =Organic Chemical; Pharmacologic Substance ;
=KETOTIFEN;
=KETOTIFEN FUMARATE 0.025 %
71. 2(H)-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, Monohydrochloride
[The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function. ( NCI )] (UMLS (NCI) C0771840) 4-(2-(Dipropylamino)ethyl)-2-indolinone Monohydrochloride;
Ropinirole Hydrochloride;
ROPINIROLE HYDROCHLORIDE PREPARATION;
SK&F 101468-A =Organic Chemical; Pharmacologic Substance ;
=ROPINIROLE;
=ROPINIROLE HYDROCHLORIDE 4 MG;
ROPINIROLE HYDROCHLORIDE 0.25 MG;
ROPINIROLE HYDROCHLORIDE 0.5 MG;
ROPINIROLE HYDROCHLORIDE 2 MG;
ROPINIROLE HYDROCHLORIDE 1 MG;
ROPINIROLE HYDROCHLORIDE 5 MG;
ROPINIROLE HYDROCHLORIDE 3 MG
22. 12 hours
(UMLS (HL7) C1292430) =Temporal Concept ;
=Duration categories;
72. 2,2'-[5-(1H-1,2,4-Triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropionitrile)
[An anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Anastrozole is used to decrease estrogen production and suppress the growth of tumors that need estrogen to grow. ( NCI )] (UMLS (NCI) C0290883) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
NITRILE;
Triazoles;
=ANASTROZOLE 1 MG;
23. 12 hours post challenge
(UMLS (HL7) C1547063) =Temporal Concept =Time delay post challenge;
73. 2,3,9,10,11,12-Hexahydro-3-hydroxy-9-methoxy-8-methyl-10-(methylamino)-8,12-epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)triinden-1-one
[A synthetic derivative of staurosporine with antineoplastic activity. 7-hydroxystaurosporine inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. This agent arrests tumor cells in the G1/S of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase chk1, resulting in apoptosis. (NCI04) ( NCI )] (UMLS (NCI) C0077681) =Organic Chemical; Pharmacologic Substance ;
24. 12-HETE
[A lipoxygenase metabolite of arachidonic acid. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (MeSH) ( NCI )] (UMLS (NCI) C0044800) =Eicosanoid; Biologically Active Substance ;
74. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-Methylpropyl)-5-(2-propenyl)-
[A barbiturate that exerts its effect by mimicking the inhibitory effect of gamma-aminobutyric acid (GABA) by binding to a site, distinct from the benzodiazepine binding site, on the GABA receptor. This leads to an increase in the duration of GABA-mediated opening of chloride channels and enhances the inhibitory effect of GABA. Consequently, its physiologic effects include sedation, hypnosis, reduction of anxiety, and respiratory depression and the drug causes tolerance and dependence. ( NCI )] (UMLS (NCI) C0054234) =Organic Chemical; Pharmacologic Substance =barbiturate;
[CN301] BARBITURIC ACID DERIVATIVE, SEDATIVES/HYPNOTICS =BUTALBITAL 50 MG;
BUTALBITAL 30 MG;
25. 13-Hydroxydaunomycin
[An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Duborimycin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0057159) =Organic Chemical; Pharmacologic Substance ;
75. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-Ethyl-5-(1-methylbutyl), Monosodium Salt
[The sodium salt of pentobarbital, a short-acting barbituric acid derivative with central nervous system (CNS) depressant property. Pentobarbital sodium binds to the gamma-aminobutyric acid (GABA)-A subtype receptor, resulting in modulation of chloride transport through receptor channels and potentiation of GABA-induced increases in chloride conductance. This enhances postsynaptic responses to the inhibitory actions of GABA and causes CNS depression. In addition, this agent inhibits glutamate induced nerve depolarization and depresses voltage-activated calcium currents. ( NCI )] (UMLS (NCI) C0700349) =Organic Chemical; Pharmacologic Substance ;
=PENTOBARBITAL;
=PENTOBARBITAL NA PWDR;
PENTOBARBITAL SODIUM 60 MG;
PENTOBARBITAL SODIUM 50 MG;
PENTOBARBITAL SODIUM 50 MG/ML;
PENTOBARBITAL SODIUM 30 MG;
PENTOBARBITAL SODIUM 120 MG;
PENTOBARBITAL SODIUM 100 MG;
PENTOBARBITAL SODIUM 200 MG;
PENTOBARBITAL SODIUM 20 MG/5ML
26. 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolinium
[The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated from the bark and stem of Chondodendron tomentosum with a muscle relaxant property. Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This may lead to skeletal muscle relaxation and paralysis. ( NCI )] (UMLS (NCI) C0282372) =Organic Chemical; Pharmacologic Substance ;
=Tubocurare;
=TUBOCURARINE CHLORIDE 3 MG/ML;
76. 2-(1-H-imidazol-4-yl) Ethylamine Dihydrochloride
[A drug being studied for its ability to enhance the effectiveness of IL-2 in treating acute myeloid leukemia. ( NCI )] (UMLS (NCI) C0543456) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine
27. 14-Hydroxydaunorubicin Hydrochloride
[The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. ( NCI )] (UMLS (NCI) C0546861) =Organic Chemical; Pharmacologic Substance =(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione;
=DOXORUBICIN HYDROCHLORIDE 10 MG;
DOXORUBICIN HYDROCHLORIDE 100 MG;
DOXORUBICIN HYDROCHLORIDE 150 MG;
DOXORUBICIN HYDROCHLORIDE 2 MG/ML;
DOXORUBICIN HYDROCHLORIDE 200 MG;
DOXORUBICIN HYDROCHLORIDE 50 MG;
DOXORUBICIN HYDROCHLORIDE 20 MG;
DOXORUBICIN HYDROCHLORIDE 5 MG/ML
77. 2-(1-Hexyloxyethyl)-2-Devinyl Pyropheophorbide-a
[2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a. A drug that is used in photodynamic therapy that is absorbed by tumor cells; when exposed to light, it becomes active and kills the cancer cells. ( NCI )] (UMLS (NCI) C0248392) =Organic Chemical; Pharmacologic Substance ;
28. 15H-Pyrrolol[2,1-f][1,15,4,7,10,20]dioxatetraazacyclotri-cosine, Cyclic Peptide Deriv. (9CI)
[A cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates caspase, thereby inducing apoptosis, and prevents eukaryotic elongation factor 2 (eEF-2)-dependent translocation, thereby inhibiting protein synthesis. This agent also has immunosuppressive and antiviral properties. (NCI04) ( NCI )] (UMLS (NCI) C0936059) 1-Oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
Didemnin;
Didemnin B;
L-Tyrosine, N-[1-[N-[4-[[3-hydroxy-4-[[N-[N-[1-(2-hydroxy-1-oxopropyl)- L-prolyl]-N-methyl-L-leucyl]-L-threonyl]amino-5-methyl- 1-oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
L-Tyrosine, N-[1-[N-[4-[[3-Hydroxy-4-[[N-[N-[1-(2-hydroxy-1-oxopropyl)- L-prolyl]-N-methyl-L-leucyl]-L-threonyl]amino-5-methyl-1-oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
=Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
78. 2-Hydroxy-1,2,3-propanetricarboxylic Acid
[A tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients and is used as a preservative. It is also used as an acidulant to control pH and acts as an anticoagulant by chelating calcium in blood. ( NCI )] (UMLS (NCI) C0055819) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =[TN410] CITRATES;
2-Hydroxy-1,2,3-propanetricarboxylic Acid;
[PH000] PHARMACEUTICAL AIDS / REAGENTS;
=Citrate of Magnesia;
CITRATE;
CITRIC ACID More…
29. 166 Holmium-DOTMP
[A drug containing a radioactive isotope that is used in the diagnosis and treatment of cancer. ( NCI )] (UMLS (NCI) C1130449) Ho 166 DOTMP;
Holmium Ho 166 DOTMP;
=Organophosphorus Compound; Indicator, Reagent, or Diagnostic Aid
79. 2-Hydroxy-1,2,3-propanetricarboxylic Acid, Calcium Salt (2:3)
[The citrate salt of calcium. An element necessary for normal nerve, muscle, and cardiac function, calcium as the citrate salt helps to maintain calcium balance and prevent bone loss when taken orally. This agent may also be chemopreventive for colon and other cancers. (NCI04) ( NCI )] (UMLS (NCI) C0108101) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =[TN402] CALCIUM;
[TN410] CITRATES;
CITRATE;
TO BE DELETED INGREDIENT PREPARATIONS =CALCIUM (AS CITRATE) 200 MG;
CALCIUM (AS CITRATE) 500 MG;
LONALAC POWDER,ORAL;
CALCIUM CITRATE 1040 MG;
CALCIUM CITRATE 315 MG;
CALCIUM CITRATE 950 MG;
30. 17 hydroxycorticosteroid
[A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal function. They are used systemically in the free alcohol form, but with esterification of the hydroxy groups, topical effectiveness is increased. ( MSH )] (UMLS (CSP) C0000163) =Steroid; Hormone ;
80. 2-Hydroxy-1,2,3-propanetricarboxylic Acid, Potassium Salt
[The potassium salt form of citrate with alkalinizing property. Following absorption, potassium citrate causes increased plasma bicarbonate concentration, thereby raising blood and urinary pH. A simultaneous decrease in calcium ion activity occurs as a result of increasing calcium complex formation with dissociated anions. Levels of urinary citrate are increased due to modification of the renal handling of citrate. By promoting excretion of free bicarbonate ion and by increasing urinary pH in addition to an increased ionization of uric acid to more soluble urate ions, this agent exerts the alkalizing and anti-urolithic effect. ( More…
31. 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic Acid, gamma Lactone, Acetate
[potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules; used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis; its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. ( CSP )] (UMLS (NCI) C0037982) =Steroid; Pharmacologic Substance =aldosterone inhibitor;
LACTONE;
C21 steroid;
Pregnenes;
[CV704] POTASSIUM-SPARING/COMBINATIONS DIURETICS;
=SPIRONOLACTONE POWDER (GM);
SPIRONOLACTONE 100 MG;
SPIRONOLACTONE 25 MG;
SPIRONOLACTONE 50 MG;
81. 2-Hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
(UMLS (NCI) C0122812) =Organic Chemical; Pharmacologic Substance
32. 1H-1,2,3-Triazole-4-carboxamide, 5-amino-1-((3,5-dichloro-4(4-chlorobenzoyl)phenyl)methyl)
[An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. ( NCI )] (UMLS (NCI) C0064494) =Organic Chemical; Pharmacologic Substance ;
82. 2-Hydroxy-4-methoxybenzophenone
[A benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage. ( NCI )] (UMLS (NCI) C0069803) =Organic Chemical; Pharmacologic Substance ;
=Benzophenones;
[DE300] SUN PROTECTANTS/SCREENS, TOPICAL =LANOLIN/MINERAL OIL/OXYBENZONE OIL,TOP;
OCTYL METHOXYCINNAMATE/OCTYL SALICYLATE/OXYBENZONE SPF-15 LOTION;
OXYBENZONE/PABA (PRE-SUN 46) LOTION;
OXYBENZONE/PADIMATE O LOTION;
OXYBENZONE/PETROLATUM OINT,TOP;
SUNSCREEN-15 PABA-FREE COMBINATION GEL;
SUNSCREEN-30 PABA-FREE COMBINATION LOTION;
OXYBENZONE 6 %;
OXYBENZONE 2 %;
OXYBENZONE 2.3 %;
OXYBENZONE 5 %;
OXYBENZONE 3 %;
ALPHA KERI BATH OIL;
BATH OIL;
AMINOBENZOIC ACID/BENZOPHENONE LOTION (ML);
THERI BATH OIL;
NUTRADERM BATH OIL
33. 1H-1,2,4-Triazol-3-Amine
[A colorless, odorless crystalline, aromatic amine with a bitter taste. Amitrole is a widely used herbicide for nonfood croplands to control annual and perennial grass type weeds, pondweeds and broad leaf. This substance has a very low acute toxicity in humans and is characterized by skin rash, diarrhea, nausea, vomiting and nose bleeds. Amitrole is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0002602) =Organic Chemical; Hazardous or Poisonous Substance
83. 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic Acid
[A synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug, antiinflammatory Sulfasalazine acts locally in the intestine through its active metabolites, sulfamide 5-aminosalicylic acid and salicylic acid, by a mechanism that is not clear. It appears inhibit cyclooxygenase and prostaglandin production and is used in the management of inflammatory bowel diseases. (NCI04) ( NCI )] (UMLS (NCI) C0036078) =Organic Chemical; Pharmacologic Substance =sulfonamide;
[GA900] GASTRIC MEDICATIONS, OTHER =SULFASALAZINE 500 MG;
SULFASALAZINE 250 MG/5ML;
34. 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, Monopotassium Salt, compound with Potassium Hydroxide
[A benzodiazepine with anxiolytic, sedative, hypnotic, and anticonvulsant properties. Clorazepate dipotassium exerts its effect by de-activating the nervous system through potentiation of the inhibitory effect of gamma-aminobutyric acid (GABA) on the GABA-A receptors by binding to a site that is distinct from the GABA binding site. Its inhibitory effect is caused by an increase in GABA-mediated chloride channel opening events, leading to hyperpolarization and synaptic inhibition. ( NCI )] (UMLS (NCI) C0009033) =Organic Chemical; Pharmacologic Substance ;
=benzodiazepine;
CLORAZEPATE PREPARATION =CLORAZEPATE DIPOTASSIUM 15 MG;
CLORAZEPATE DIPOTASSIUM 22.5 MG;
CLORAZEPATE DIPOTASSIUM 7.5 MG;
CLORAZEPATE DIPOTASSIUM 11.25 MG;
CLORAZEPATE DIPOTASSIUM 3.75 MG;
84. 2-Hydroxyamino-2-ethanal
[A urea analogue with bacterial urease inhibiting activity. Acetohydroxamic acid is used as adjunctive therapy in the treatment of urinary tract infections caused by urease-producing bacteria. In addition, this drug is used in the prophylaxis and treatment of struvite renal calculi, whose formation is favored by urease-producing bacteria, by dissolving renal stones as well as preventing the formation of new crystals. (NCI05) ( NCI )] (UMLS (NCI) C0050451) =Organic Chemical; Pharmacologic Substance =Hydroxamic Acids;
Unclassified Ingredient Preparations =ACETOHYDROXAMIC ACID 250 MG;
35. 1H-Benz(de)isoquinolin-1-one, 2-(3S)-1-azabicyclo(2.2.2)oct-3-yl-2,3,3a,4,5,6-hexahydro-, Monohydrochloride,(3aS)-
[The hydrochloride salt form of palonosetron, a carbazole derivative and a selective serotonin receptor antagonist with antiemetic properties. Palonosetron competitively blocks the action of serotonin at 5-HT3 receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. ( NCI )] (UMLS (NCI) C1310734) PALONOSETRON HCL UNIDENTIFIED;
PALONOSETRON HCL UNIDENTIFIED;
PALONOSETRON HYDROCHLORIDE;
=Organic Chemical; Pharmacologic Substance ;
85. 2-Hydroxybenzoic Acid
[A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics. (From Dorland's, 28th ed) ( MSH )] (UMLS (NCI) C0036079) =Organic Chemical; Pharmacologic Substance =2-Hydroxybenzoic Acid;
Salicylic Acids;
[DE752] ANTIACNE AGENTS, TOPICAL;
[DE500] KERATOLYTICS/CAUSTICS, TOPICAL =Salicylates;
PYRITHIONE ZINC 1% SHAMPOO;
BI SUBSALICYLATE 260MG/MG AL SILICATE/SAL AC/NA SALICYLATE/30ML;
BI SUBSALICYLATE 459MG/MG AL SILICATE/SAL AC/NA SALICYLATE/30ML;
COAL TAR 5%/LASSAR PASTE,TOP;
Coal Tar / Salicylic Acid Topical Cream;
DRYTEX LOTION;
EUCALYPTUS OIL/ME SALICYLATE/PEPPERMINT OIL/SALICYLIC AC LIQ,TOP;
GORDOMATIC PWDR,TOP;
SALICYLIC ACID GEL,TOP;
SALICYLIC ACID POWDER (GM);
NAIL FUNGAL SOLN,TOP;
COAL TAR/SALICYLIC ACID LOTION;
CARMEX OINT,TOP;
SALICYLIC ACID 0.1 %;
SALICYLIC ACID 4 GM;
SALICYLIC ACID 13.57 %;
SALICYLIC ACID 40 %;
SALICYLIC ACID 0.5 %;
SALICYLIC ACID 1 %;
SALICYLIC ACID 5 %;
SALICYLIC ACID 2.5 %;
SALICYLIC ACID 12.2 %;
SALICYLIC ACID 2.35 %;
SALICYLIC ACID 26 %;
SALICYLIC ACID 6 %;
SALICYLIC ACID 50 %;
SALICYLIC ACID 12 %;
SALICYLIC ACID 1.8 %;
SALICYLIC ACID 4 %;
SALICYLIC ACID 10 %;
SALICYLIC ACID 16.7 %;
SALICYLIC ACID 30 %;
SALICYLIC ACID 2.25 %;
SALICYLIC ACID 24 %;
SALICYLIC ACID 14.2 %;
SALICYLIC ACID 1.5 %;
SALICYLIC ACID 2 %;
SALICYLIC ACID 3 %;
SALICYLIC ACID 17 %;
SALICYLIC ACID 25 %;
SALICYLIC ACID 60 %;
2-Hydroxybenzoic Acid
36. 1H-benz(de)isoquinoline-1,3(2H)-dione, 5-amino-2-(2-(dimethylamino)ethyl)
(UMLS (NCI) C0051733) =Organic Chemical; Pharmacologic Substance
86. 2-Hydroxypropanoic Acid Sodium Salt
[A sodium salt of racemic or inactive lactic acid with alkalinizing and electrolyte replenishing property. Upon metabolism, sodium lactate is converted to bicarbonate, thereby increasing plasma bicarbonate, which facilitates removal of hydrogen ion and lactate from blood stream and leads to raised blood pH. ( NCI )] (UMLS (NCI) C0142874) =Organic Chemical; Pharmacologic Substance ;
=lactate;
[TN102] IV SOLUTIONS WITH ELECTROLYTES;
[TN499] ELECTROLYTES/MINERALS, OTHER;
=MASSENGILL DISPOSABLE DOUCHE;
Carboxymethylcellulose 5 MG/ML Ophthalmic Solution;
MASSENGILL DISPOSABLE DOUCHE BELLE-MAI,VAG;
SODIUM LACTATE 5 MEQ/ML;
MASSENGILL DOUCHE,VAG;
Sodium Lactate 3.1 MG/ML;
Sodium Lactate 2.6 MG/ML;
Sodium Lactate 2.2 MG/ML;
SODIUM LACTATE 0.062 GM/100ML;
SODIUM LACTATE 0.392 GM/100ML;
SODIUM LACTATE 138 MG/100ML;
SODIUM LACTATE 155 MG/100ML;
SODIUM LACTATE 224 MG/100ML;
SODIUM LACTATE 246 MG/100ML;
SODIUM LACTATE 25 ML;
SODIUM LACTATE 280 MG/100ML;
SODIUM LACTATE 390 MG/100ML;
SODIUM LACTATE 392 MG/100ML;
SODIUM LACTATE 448 MG/100ML;
SODIUM LACTATE 50 ML;
SODIUM LACTATE 500 MG/100ML;
SODIUM LACTATE 62 MG/100ML;
SODIUM LACTATE 670 MG/100ML;
SODIUM LACTATE 672 MG/100ML;
SODIUM LACTATE 672.4 MG/100ML;
SODIUM LACTATE 89.6 MG/100ML;
SODIUM LACTATE 0.056 %;
SODIUM LACTATE 5 %;
SODIUM LACTATE 1;
PODOFILOX 0.5 %WW TOPICAL SOLUTION;
37. 1H-benzimidazol-2-ylcarbamic Acid Methyl Ester
[An anticancer drug that belongs to the family of drugs called antifungal agents. ( NCI )] (UMLS (NCI) C0065839) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
87. 2-[[(Hexadecycloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium Inner Salt
[An orally- and topically-active alkyl-phosphocholine compound with potential antineoplastic activity. Miltefosine targets cellular membranes, modulating cell membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. As an immunomodulator, miltefosine stimulates T-cells, macrophages and the expression of interleukin 3 (IL-3), granulocyte-macrophage colony stimulating factor (GM-CSF), and interferon gamma (INF-gamma). (NCI04) ( NCI )] (UMLS (NCI) C0068006) =Organophosphorus Compound; Pharmacologic Substance
38. 1H-Carbazole-6-carboxamide, 2,3,4,9-tetrahydro-3-(methylamino)-,(3R)-, Butanedioate(1:1)
[The succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine. (NCI05) ( NCI )] (UMLS (NCI) C1099777) Frovatriptan Succinate;
FROVATRIPTAN SUCCINATE UNIDENTIFIED;
=Organic Chemical; Pharmacologic Substance
88. 24 Hour Extended Release Suspension
(UMLS (HL7) C1337572) 24 Hour Extended-Release Suspension;
=Biomedical or Dental Material; ;
=Extended Release Suspension;
39. 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-
[A substance that improves the body's natural response to infection and disease. It is being studied as a topical agent (something used on the surface of the body) for the prevention of some types of cancer. It belongs to the family of drugs called biological response modifiers. ( NCI )] (UMLS (NCI) C0165032) =Organic Chemical; Pharmacologic Substance =S 26308;
[IM900] IMMUNOLOGICAL AGENTS, OTHER =IMIQUIMOD 5 %
89. 24 hours
(UMLS (HL7) C0439584) =Temporal Concept =Duration categories;
40. 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, Mononitrate
[The nitrate salt form of sertaconazole, a synthetic imidazole derivative with antifungal property. Sertaconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and the inhibition of ergosterol synthesis, an essential component of the cell membrane of fungi. This leads to a disruption of cell membrane permeability and leakage of adenine triphosphate (ATP) and other constituents from fugal cells. ( NCI )] (UMLS (NCI) C0771896) Sertaconazole Nitrate;
=Organic Chemical; Pharmacologic Substance
90. 24 hours post challenge
(UMLS (HL7) C1547070) =Temporal Concept =Time delay post challenge;
41. 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, Monohydrochloride
[The hydrochloride salt form of tetrahydrozoline, an imidazole derivative with sympathomimetic property. Applied locally to the eye or nose, tetrahydrozoline binds to and activates alpha-adrenergic receptors, resulting in vasoconstriction and decreased nasal and ophthalmic congestion. ( NCI )] (UMLS (NCI) C0148485) =Organic Chemical; Pharmacologic Substance ;
=TETRAHYDROZOLINE;
=tetrahydrozoline 0.5 MG/ML Nasal Solution;
TETRAHYDROZOLINE HYDROCHLORIDE 0.1 %;
91. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-Dioxide
[A thiazide diuretic. Bendroflumethiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment of the distal convoluted tubule in the kidney. This drug increases water, sodium, chloride, potassium and bicarbonate excretion and decreases calcium and uric acid secretion. Bendroflumethiazide is commonly used to treat hypertension, edema, and congestive heart failure. ( NCI )] (UMLS (NCI) C0004975) =Organic Chemical; Pharmacologic Substance
42. 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, Monohydrochloride
[The hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness. ( NCI )] (UMLS (NCI) C0282259) =Organic Chemical; Pharmacologic Substance ;
=NAPHAZOLINE;
=NAPHAZOLINE HYDROCHLORIDE 0.025 %;
NAPHAZOLINE HYDROCHLORIDE 0.05 %;
NAPHAZOLINE HYDROCHLORIDE 0.02 %;
NAPHAZOLINE HYDROCHLORIDE 0.1 %;
NAPHAZOLINE HYDROCHLORIDE 0.012 %
92. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-(trifluoromethyl)-, 1,1-Dioxide
[A thiazide diuretic with antihypertensive activity. Hydroflumethiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment of the distal convoluted tubule in the kidney. This results in an increase in water, sodium, chloride, potassium and bicarbonate excretion and a decrease in calcium and uric acid secretion. (NCI05) ( NCI )] (UMLS (NCI) C0020273) =Organic Chemical; Pharmacologic Substance ;
=benzothiadiazine;
[CV701] THIAZIDES/RELATED DIURETICS =HYDROFLUMETHIAZIDE 50 MG
43. 1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-
[A drug that increases the effectiveness of radiation therapy. ( NCI )] (UMLS (NCI) C0059682) =Organic Chemical; Pharmacologic Substance ;
93. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-2-methyl-3-(((2,2,2-trifluoroethyl)thio)methyl)-, 1,1-Dioxide
[A sulfonamide derivative and a synthetic thiazide with diuretic, antihypertensive and anti-urolithic properties. By blocking the Na/Cl transporter, polythiazide inhibits reabsorption of sodium and chloride in the proximal and distal convoluted tubule of the kidney, resulting in increased excretion of water and electrolytes (sodium, potassium, chloride, magnesium, and bicarbonate) and subsequent reversal of hypertension. In addition, this agent exerts its anti-urolithic effect by decreasing calcium and uric acid excretion. ( NCI )] (UMLS (NCI) C0032613) =Organic Chemical; Pharmacologic Substance ;
=benzothiadiazine;
[CV701] THIAZIDES/RELATED DIURETICS =POLYTHIAZIDE 0.5 MG;
POLYTHIAZIDE 1 MG;
POLYTHIAZIDE 2 MG;
POLYTHIAZIDE 4 MG;
44. 1H-Imidazole-2-methanamine, 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-, Phosphate(1:1)
[The phosphate salt of antazoline, an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, gastrointestinal and bronchial smooth muscles. These histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Antazoline is used to provide symptomatic relieve of allergic symptoms. ( NCI )] (UMLS (NCI) C0003144) =Organic Chemical; Pharmacologic Substance
94. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-Dioxide
[A thiazide diuretic with antihypertensive activity. Methyclothiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment of the distal convoluted tubule in the kidney. This results in an increase in water, sodium, chloride, potassium and bicarbonate excretion and a decrease in calcium and uric acid secretion. ( NCI )] (UMLS (NCI) C0025696) =Organic Chemical; Pharmacologic Substance ;
=benzothiadiazine;
[CV701] THIAZIDES/RELATED DIURETICS =NIVEA SKIN OIL;
METHYCLOTHIAZIDE 2.5 MG;
METHYCLOTHIAZIDE 5 MG
45. 1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-
[cytotoxic alkylating agent used as an antineoplastic primarily for treatment of malignant melanoma and in combination chemotherapy for Hodgkin's disease and sarcomas; administered intravenously; abbreviated DTIC. ( CSP )] (UMLS (NCI) C0010927) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
imidazole;
Triazene Compound;
imidazole carboxamide =3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide;
DACARBAZINE 100 MG;
DACARBAZINE 200 MG;
95. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-Dioxide
[A thiazide diuretic with antihypertensive activity. Trichlormethiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in water, sodium, chloride, bicarbonate, and potassium secretion and a decrease in calcium and uric acid secretion. ( NCI )] (UMLS (NCI) C0040899) =Organic Chemical; Pharmacologic Substance =[CV701] THIAZIDES/RELATED DIURETICS;
6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide =TRICHLORMETHIAZIDE 4 MG
46. 1H-Imidazole-5-Carboxylic Acid, 1-((1R)-1-phenylethyl)-, Ethyl Ester
[An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through GABA-A receptor. The action enhances the inhibitory effect of GABA on the central nervous system by causing chloride channel opening events which leads to membrane hyperpolarization. ( NCI )] (UMLS (NCI) C0015131) =Organic Chemical; Pharmacologic Substance ;
=imidazole;
[CN203] GENERAL ANESTHETICS, OTHER =ETOMIDATE 2 MG/ML
96. 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-
[benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia. ( CSP )] (UMLS (NCI) C0029997) =Organic Chemical; Pharmacologic Substance ;
=benzodiazepine;
Benzodiazepinones;
tranquilizer;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS =OXAZEPAM 10 MG;
OXAZEPAM 15 MG;
OXAZEPAM 30 MG;
47. 1H-Imidazole-5-carboxylic Acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
[A synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland, thereby competing angiotensin II binding to the receptor. This prevents angiotensin II-induced vasoconstriction and decreases aldosterone production, thereby preventing aldosterone-stimulated sodium retention and potassium excretion. ( NCI )] (UMLS (NCI) C0386393) =Organic Chemical; Pharmacologic Substance ;
=Olmesartan;
Unclassified Ingredients =OLMESARTAN MEDOXOMIL 20 MG;
OLMESARTAN MEDOXOMIL 40 MG;
OLMESARTAN MEDOXOMIL 5 MG
97. 2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-
[A synthetic benzodiazepine derivative with anxiolytic, sedative and hypnotic properties. Quazepam and its major metabolite 2-oxoquazepam potentiate gamma-aminobutyric acid (GABA) activity by binding to the benzodiazepine-1 recognition site (BZ-1) within the GABA-A receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of GABA-activated chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreased neuronal excitability. ( NCI )] (UMLS (NCI) C0072828) =Organic Chemical; Pharmacologic Substance =[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS;
Unclassified Ingredients =QUAZEPAM 15 MG;
QUAZEPAM 7.5 MG;
48. 1H-imidazo[4,5-f]quinoline, acetamide deriv
[A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has been associated with significant cardiotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0050565) =Organic Chemical; Pharmacologic Substance ;
98. 2H-1-Benzopyran-2-one
[oxygen containing heterocyclic compound, obtainable naturally from several plants, or produced synthetically from an amino acid of phenylalanine; it is used for the preparation of drugs especially anticoagulants such as bishydroxycoumarin (dicoumarol) and warfarin (coumadin); coumarin glycosides such as dicoumarol and warfarin, are widely used as rodenticides. ( CSP )] (UMLS (NCI) C0010206) =Organic Chemical; Pharmacologic Substance =pyrone;
=furocoumarin;
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone;
49. 1H-Indene-3-acetic Acid, 5-Fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene), (Z)
(UMLS (NCI) C0953857) =Organic Chemical; Pharmacologic Substance
99. 2H-10,4a-Iminoethanophenanthren-6-ol, 1,3,4,9,10,10a-hexahydro-11-methyl-, Tartrate
[The tartrate salt form of levorphanol, a synthetic phenanthrene with potent opioid analgesic activity. Levorphanol tartrate mimics the actions of endogenous peptides at CNS opioid receptors, thereby producing the characteristic morphine-like effects on the mu-opioid receptor, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. ( NCI )] (UMLS (NCI) C0596008) =Organic Chemical; Pharmacologic Substance =LEVORPHANOL;
=LEVORPHANOL TARTRATE 2 MG;
LEVORPHANOL TARTRATE 2 MG/ML
50. 1H-Indole-2-carboxylic Acid, 1-(2-((1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-,(2S-(1(R*(R*))2alpha,3abeta,7abeta))-, compound with 2-Methyl-2-propanamine(1:1)
[The tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive property. Upon hydrolysis, perindopril erbumine is converted to its active form perindoprilat, which inhibits ACE, thereby blocks the conversion of angiotensin I to angiotensin II. This prevents angiotensin II-mediated vasoconstriction, decreases angiotensin II-stimulated aldosterone secretion from the adrenal cortex, and consequently promotes diuresis and natriuresis. ( NCI )] (UMLS (NCI) C0244718) =Organic Chemical; Pharmacologic Substance ;
=Perindopril;
=PERINDOPRIL ERBUMINE 2 MG;
PERINDOPRIL ERBUMINE 4 MG;
PERINDOPRIL ERBUMINE 8 MG
100. 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-
[diphenylbutylpiperidine that is used as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. ( CSP )] (UMLS (NCI) C0031935) =Organic Chemical; Pharmacologic Substance =benzimidazole;
[CN700] ANTIPSYCHOTICS;
[CN900] CNS MEDICATIONS, OTHER;
=PIMOZIDE 2 MG;
PIMOZIDE 1 MG;

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