- 1. Ibandronate Sodium
- [The sodium salt form of ibadronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain. ( NCI )] (UMLS (NCI) C0772244) =Organic Chemical; Pharmacologic Substance
| - 8. Ibopamine
- (UMLS (NCI) C0123043) =Organic Chemical; Pharmacologic Substance
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- 2. Ibandronic Acid
- [A third-generation amino-bisphosphonate with anti-resorptive and anti-hypercalcemic activity. Ibandronic acid binds to and adsorbs onto the surface of hydroxyapatite crystals in the bone matrix, thereby preventing osteoclast resorption. This agent also inhibits farnesyl pyrophosphate synthase, an enzyme involved in the mevalonate pathway. Inhibition of this enzyme prevents the formation of isoprenoids, thereby leading to a reduction in the farnesylation and geranylgeranylation of signaling proteins of G protein-coupled signaling, and, eventually, inducing apoptosis of osteoclasts. By inhibiting osteoclast-mediated bone resorption, ibandronic acid increases bone mineral density, decreases bone remodeling and turnover, as well as reduces bone pain. ( NCI )] (UMLS (NCI) C0379200) =Organic Chemical; Pharmacologic Substance
| - 9. ibotenate
- [3-hydroxy-5-isoxazole alpha-aminoacetate, an excitatory aminoacid agonist for certain quisqualate-sensitive glutamate receptors in the brain; it is a neurotoxin that selectively ablates neuronal cell bodies while sparing axonal projections. ( CSP )] (UMLS (CSP) C0178705) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =alkaloid;
Amino Acids, Cyclic;
hallucinogen;
Fungal Toxin;
Neurotoxin;
EAA |
- 3. IBC
- [The capacity of iron-binding protein in serum (transferrin) to bind serum iron. ( NCI )] (UMLS (NCI) C0373658) =Laboratory Procedure
| - 10. ibotenate receptor
- [ ] (UMLS (CSP) C0598524) =Amino Acid, Peptide, or Protein; Receptor
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- 4. IBD
- [chronic, non-specific inflammation of the gastrointestinal tract; etiology may be genetic or environmental. ( CSP )] (UMLS (NCI) C0021390) =Disease or Syndrome =Enteritis;
Intestinal Diseases =Colitis, Ulcerative;
Crohn Disease;
Colitis, Ulcerative;
Crohn Disease | - 11. IBP2
- [Encoded by human IGFBP2 Gene, cysteine-rich high molecular weight secreted 328-aa 35-kD Insulin-Like Growth Factor-Binding Protein 2 precursor contains an IGFBP domain and a thyroglobulin type-I domain. IGF-binding proteins prolong plasma IGF half-life and alter IGF interaction with cell surface receptors. The predominant form in plasma (150-kD) contains IGF-BP53 with apparent molecular mass of 53-kD. IGFBP2 binds IGF-II with high affinity more than IGF-I. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0123257) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 5. Ibizan Hound
- [The Ibizan Hound is an agile, deer-like, athletic hound that has a long, arched neck, long wedge-shaped head, and very large, triangular ears which stand up when the dog is alert. The rose or flesh-colored nose has a slightly convex shape called "Roman nose." The Ibizan Hound is "hare-footed," with long toes. There are three varieties of Ibizan: smooth-haired, long-haired, and wire-haired. Colors are white and red, white and tan, or solid white or red. Height: 22-29 inches (56-74 cm.) Weight: 42-55 pounds (19-25 kg.) ( NCI )] (UMLS (NCI) C0324381) =Mammal
| - 12. Ibritumomab Tiuxetan
- [An immunoconjugate of monoclonal antibody ibritumomab conjugated with the linker-chelator tiuxetan. Ibritumomab is a murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. This linker-chelator provides a high affinity, conformation restricted chelation site for Indium-111 or Yttrium-90 to be used in relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin's lymphoma, including patients with rituximab refractory follicular non-Hodgkin's lymphoma. ( NCI )] (UMLS (NCI) C0877880) IBRITUMOMAB TIUXETAN PREPARATION;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =[AN600] ANTINEOPLASTIC RADIOPHARMACEUTICALS;
Unclassified Ingredients =IBRITUMOMAB TIUXETAN 1.6 MG/ML;
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- 6. iboga alkaloid
- [ ] (UMLS (CSP) C0598647) =Organic Chemical; Pharmacologic Substance ;
| - 13. Ibudilast
- (UMLS (NCI) C0123047) =Organic Chemical; Pharmacologic Substance
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- 7. ibogaine
- [indole alkaloid with antidepressant and euphoric properties; appears to modulate tolerance to opiates. ( CSP )] (UMLS (CSP) C0020737) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =alkaloid;
Indole;
psychotropic drug;
methoxyindole;
[XX000] MISCELLANEOUS AGENTS;
=IBOGAINE HYDROCHLORIDE;
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