- 1. 131I-HuCC49-deltaCH2
- [A radioimmunoconjugate consisting of the humanized monoclonal antibody (MoAb) CC49 having CH2 domain deleted, labeled with iodine 131 (I-131). MoAb CC49-deltaCH2 recognizes an epitope of the tumor-associated glycoprotein (TAG) 72 that is expressed by a wide range of cancers, including colorectal, gastric, pancreatic, ovarian, endometrial, breast, non-small cell lung, and prostate cancers. I-131 MoAb CC49-delta CH2 delivers beta and gamma radiation emitting I-131 nuclide directly to tumor cells that express TAG-72, thereby allowing imaging and/or treatment of cancers. ( NCI )] (UMLS (NCI) C1134477) 131I-MOAB CC49-deltaCH2;
I131 MOAB CC49-deltaCH2;
Iodine I 131 Monoclonal Antibody CC49-deltaCH2 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor | |
home
