- 1. IL1
- [macrophage produced interleukin that induces the production of interleukin 2 by T cells that have been stimulated by antigen or mitogen; at least two types, alpha and beta, exist; interleukin 1 or a similar protein is also produced by epithelial cells and stimulates fibroblast proliferation and release of proteolytic enzymes and prostaglandins in inflammatory processes. ( CSP )] (UMLS (NCI) C0021755) =Amino Acid, Peptide, or Protein; Immunologic Factor =Cytokine;
hematopoietic growth factor | - 7. IL15
- [This gene is involved in the regulation of memory T cells and cytokine production. ( NCI )] (UMLS (NCI) C1334105) IL15 Gene;
Interleukin 15 Gene;
=Gene or Genome |
- 2. IL10
- [This gene plays an anti-inflammatory role in immune processes and is involved in a variety of diseases. ( NCI )] (UMLS (NCI) C1334098) IL10 Gene;
Interleukin 10 Gene =Gene or Genome | - 8. IL16
- [Interleukin-16, encoded by the IL16 gene, is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. As a ligand for CD4, the signaling process of this cytokine is mediated by CD4. It stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils as well as induces T-lymphocyte expression of interleukin 2 receptor. The product of this gene undergoes proteolytic processing, which yields two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is involved in the proteolytic processing of this protein. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. (From LocusLink, Swiss-Prot and NCI) ( NCI )] (UMLS (NCI) C0065337) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
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- 3. IL11
- [This gene plays a role in the regulation of cell proliferation and differentiation. ( NCI )] (UMLS (NCI) C1334100) IL11 Gene;
Interleukin 11 Gene =Gene or Genome | - 9. IL16
- [This gene is involved in chemotaxis and is a pro-inflammatory factor. ( NCI )] (UMLS (NCI) C1334106) IL16 Gene;
Interleukin 16 (Lymphocyte Chemoattractant Factor) Gene;
=Gene or Genome |
- 4. IL13
- [T lymphocyte derived cytokine that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B lymphocytes; it appears to play a role in regulating inflammatory and immune responses. ( CSP )] (UMLS (NCI) C0214743) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
=Cytokine;
| - 10. IL18
- [This gene is involved in the induction and regulation of pro-inflammatory cytokines. ( NCI )] (UMLS (NCI) C1334109) IL18 Gene;
Interleukin 18 (Interferon-Gamma-Inducing Factor) Gene;
=Gene or Genome |
- 5. IL13
- [This gene is involved in inflammatory processes and has been identified as a therapeutic target in persons with asthma. ( NCI )] (UMLS (NCI) C1334103) IL13 Gene;
Interleukin 13 Gene =Gene or Genome | - 11. IL19
- [This gene is involved in the induction and regulation of inflammatory cytokines. ( NCI )] (UMLS (NCI) C1334110) IL19 Gene;
Interleukin 19 Gene;
=Gene or Genome |
- 6. IL15
- [cytokine that stimulates the proliferation of T lymphocytes and shares biological activities with interleukin 2; it also can induce B lymphocyte proliferation and differentiation. ( CSP )] (UMLS (NCI) C0254610) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
=lymphokine;
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