- 1. Iveegam EN
- (UMLS (NCI) C1170359) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 2. IVERMECTIN
- [A macrocyclic lactone derived from Streptomyces avermitilis with antiparasitic activity. Ivermectin exerts its anthelmintic effect via activating glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells. Distinct from the channel opening induced by endogenous glutamate transmitter, ivermectin-activated channels open very slowly but essentially irreversibly. As a result, neurons or muscle cells remain at either hyperpolarisation or depolarization state, thereby results in paralysis and death of the parasites. Ivermectin does not readily pass mammal blood-brain barrier to central nervous system where glutamate-gated chloride channels locate, hence the hosts are relatively resistant to the effects of this agent. ( NCI )] (UMLS (NCI) C0022322) =Organic Chemical; Pharmacologic Substance =Anthelminthics;
disaccharide;
LACTONE;
=IVERMECTIN 6 MG;
IVERMECTIN 3 MG |
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