- 1. Moexipril HCl
- [The hydrochloride salt form of moexipril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexipril hydrochloride is hydrolized into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. Moexipril hydrochloride also directly suppresses renin release. ( NCI )] (UMLS (NCI) C0771294) Moexipril Hydrochloride;
MOEXIPRIL HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =moexipril;
=MOEXIPRIL HYDROCHLORIDE 7.5 MG;
MOEXIPRIL HYDROCHLORIDE 15 MG | - 2. Moexiprilat
- [A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexiprilat competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. This agent also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. ( NCI )] (UMLS (NCI) C0209137) =Organic Chemical; Pharmacologic Substance
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