- 1. MYH11
- [This gene plays a regulatory role in muscle contraction and the required ATP hydrolysis. ( NCI )] (UMLS (NCI) C1334538) MYH11 Gene;
Myosin, Heavy Polypeptide 11, Smooth Muscle Gene =Gene or Genome | - 2. MYH11
- [Smooth Muscle Myosin Heavy Chain 11, encoded by the human MYH11 gene belonging to the myosin heavy chain family. This protein is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The pericentric inversion of chromosome 16 produces a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Additional splice variants exist. (from LocusLink) ( NCI )] (UMLS (NCI) C1336017) Myosin Heavy Chain, Smooth Muscle Isoform;
Myosin, Heavy Polypeptide 11, Smooth Muscle;
Myosin, Smooth Muscle, Heavy Chain 11;
SMHC;
SMMHC;
Smooth Muscle Myosin Heavy Chain 11 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
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