- 1. (OC-6-33)-dichlorodihydroxybis(2-propanamine)platinum
- [A synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death. Although less prone to glutathione inactivation compared to cisplatin, resistance to this agent has been observed in vitro due to repair of platination damage by tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0057856) =Organic Chemical; Pharmacologic Substance ;
| - 2. OCD
- [A type of osteochondritis in which articular cartilage and associated bone becomes partially or totally detached to form joint loose bodies. Affects mainly the knee, ankle, and elbow joints. ( MSH )] (UMLS (CSP) C0029421) =Disease or Syndrome ;
=osteochondritis;
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