- 1. 1,1',1"-phosphinothioylidynetrisaziridine
- [alkylating agent used as an antineoplastic in the treatment of carcinoma of the breast, ovary, and bladder, malignant infusions and lymphomas. ( CSP )] (UMLS (NCI) C0039871) =Organophosphorus Compound; Pharmacologic Substance; Hazardous or Poisonous Substance =[AN000] ANTINEOPLASTICS;
Organothiophosphorus Compounds;
Triethylenephosphoramide;
Aminoethylene;
Antineoplastic Alkylating Agent;
=THIOTEPA 15 MG | - 51. phosphatidylinositol
- [derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myoinositol. ( CSP )] (UMLS (CSP) C0031621) =Lipid; Biologically Active Substance ;
=Glycerophospholipids;
=glycosylphosphatidylinositol;
|
- 2. 1-Phosphatidylinositol 3-Kinase
- [An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. (from LocusLink) ( NCI )] (UMLS (NCI) C0044602) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;
| - 52. Phosphatidylinositol 4,5-bisphosphate
- [Phosphatidylinositol 4,5-Diphosphate; PIP2. A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate (IP3) and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994) ( NCI )] (UMLS (NCI) C0070798) =Organophosphorus Compound; Biologically Active Substance
|
- 3. 1-Phosphatidylinositol 3-Kinase
- [Phosphoinositide-3-Kinase, Catalytic, Gamma Polypeptide, encoded by the PIK3CG gene, belongs to the PI3/PI4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. (from LocusLink) ( NCI )] (UMLS (NCI) C0285761) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 53. Phosphatidylinositol 4-Kinase, Catalytic, Beta Polypeptide Gene
- [This gene is involved in signal transduction and cell organization/biogenesis. ( NCI )] (UMLS (NCI) C1335216) PIK4CB;
PIK4CB Gene =Gene or Genome ;
|
- 4. 1-Phosphatidylinositol Phosphodiesterase
- [Encoded by human PLCG2 Gene, 1265-aa 148-kDa Phospholipase C Gamma 2 is a crucial enzyme that generates DAG and IP3 second messengers in the transmembrane signaling of ligand-activated growth factor receptors. Containing a PI-PLC X-box catalytic domain, a PI-PLC Y-box catalytic domain, a C2 domain, a PH domain, 2 SH2 domains, and an SH3 domain, PLCG2 phospholipase activity increases upon phosphorylation on tyrosine residues following activation of growth factor and immune system receptors. (NCI) ( NCI )] (UMLS (NCI) C1377870) 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Gamma 2;
EC 3.1.4.11;
Phosphatidylinositol-Specific Phospholipase C-Gamma;
Phosphoinositide Phospholipase C;
Phospholipase C Gamma 2;
Phospholipase C, Gamma 2 (Phosphatidylyinositol-specific);
Phospholipase C-Gamma-2;
PI-Specific PLC Gamma;
PLCG2;
PLC-Gamma-2;
PLC-IV =Amino Acid, Peptide, or Protein; Enzyme | - 54. Phosphatidylinositol-4-Phosphate 5-Kinase, Type II, Alpha Gene
- [This gene plays a role in cellular differentiation, growth and proliferation. ( NCI )] (UMLS (NCI) C1335219) PIP5K2A;
PIP5K2A Gene =Gene or Genome ;
|
- 5. 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 3
- [Expressed in many tissues by human PLCB3 Gene, 1234-aa 139-kDa membrane-bound Phospholipase C Beta 3 contains a catalytic PI-PLC X-box domain, a catalytic PI-PLC Y-box domain, and a C2 domain. Activated in response to stimulation by hormones, growth factors, neurotransmitters, and other ligands, PLCB3 is a key enzyme in initiating receptor-mediated signal transduction by mediating production of DAG and IP3 second messengers. (NCI) ( NCI )] (UMLS (NCI) C1377871) Phosphoinositide Phospholipase C;
Phospholipase C Beta 3;
Phospholipase C Beta 3, Phosphatidylinositol-Specific;
PLCB3;
PLC-Beta-3 =Amino Acid, Peptide, or Protein; Enzyme | - 55. Phosphatidylinositol-4-Phosphate 5-Kinase, Type II, Beta Gene
- [This gene is involved in signal transduction. ( NCI )] (UMLS (NCI) C1335220) PIP5K2B;
PIP5K2B Gene =Gene or Genome ;
|
- 6. 1-Phosphatidylinositol-4-Phosphate 5-Kinase
- [Expressed ubiquitously (high in brain) by human PIP5K2A Gene (PtdIns(4)P-5-Kinase Family), 406-aa 46-kDa Phosphatidylinositol-4-Phosphate 5-Kinase Type II Alpha is a likely homodimer that catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-biphosphate, the precursor to second messengers of phosphoinositide signal transduction pathways involved in regulation of secretion, cell proliferation, differentiation, and motility. PIP5K2A does not show homology to other kinases, but the protein does exhibit kinase activity. (NCI) ( NCI )] (UMLS (NCI) C1368110) 1-Phosphatidylinositol-4-Phosphate Kinase;
Diphosphoinositide Kinase;
Phosphatidylinositol-4-Phosphate 5-Kinase Type II Alpha;
PIP5K2A;
PIP5KII-Alpha;
PIPK;
PtdIns(4)P-5-Kinase;
Type II Phosphatidylinositol-4-Phosphate 5-Kinase 53 K;
=Amino Acid, Peptide, or Protein; Enzyme | - 56. phosphatidylserine
- [derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a serine moiety. ( CSP )] (UMLS (CSP) C0031623) =Lipid =Glycerophospholipids;
|
- 7. 1-Phosphatidylinositol-4-Phosphate Kinase
- [Abundantly expressed (6.3-kb mRNA) in many tissues, human PIP5K2B Gene (PtdIns(4)P-5-Kinase Family) encodes 416-aa plasma membrane targeted Phosphatidylinositol-4-Phosphate 5-Kinase Type II Beta, a homodimer 78% identical in sequence to PIP5K2A that catalyzes phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate, precursor to second messengers of phosphoinositide signal transduction pathways involved in regulation of secretion, cell proliferation, differentiation, and motility. PIP5K isoforms possess almost no homology to kinase motifs in other phosphatidylinositol, protein, and lipid kinases. Conserved basic residues may form a dual specificity site for phosphatidylinositol 3- and 5-phosphates. PIP5K2B specifically interacts with the juxtamembrane region of TNFR1; PIP5K2B activity is increased by TNF-alpha. (NCI) ( NCI )] (UMLS (NCI) C1368108) Diphosphoinositide Kinase;
Phosphatidylinositol-4-Phosphate 5-Kinase Type II Beta;
PIP5KIIB;
PIPKII-Beta;
PTDINS(4)P-5-Kinase;
=Amino Acid, Peptide, or Protein; Enzyme | - 57. phosphine
- [PH3, a gas used in organic syntheses and solid state electronics components; a chemically unrelated dye, chrysaniline yellow, is sometime called phosphine but should be indexed as ANILINE DYE. ( CSP )] (UMLS (CSP) C0070813) =Hazardous or Poisonous Substance; Inorganic Chemical =phosphorus compound;
|
- 8. 3-Phosphoinositide Dependent Protein Kinase-1
- [3-Phosphoinositide Dependent Protein Kinase-1, encoded by the PDPK1 gene, belongs to the Ser/Thr family of protein kinases. This protein phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, p70S6K and p90S6K/RSK. It may play a general role in signaling processes and in development (by similarity). It becomes cytoplasmic and membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane. Three isoforms exist from alternative splicing and Isoform 3 is catalytically inactive. (from LocusLink) ( NCI )] (UMLS (NCI) C0541150) =Amino Acid, Peptide, or Protein; Enzyme
| - 58. phosphite
- [PO3(3-). ( CSP )] (UMLS (CSP) C0206386) =Chemical Viewed Structurally =phosphorus compound;
|
- 9. 3-Phosphoinositide Dependent Protein Kinase-1 Gene
- [This gene plays a role in cellular signaling and development. ( NCI )] (UMLS (NCI) C1335204) PDPK1;
PDPK1 Gene =Gene or Genome | - 59. phosphite ester
- [ ] (UMLS (CSP) C0599120) =Inorganic Chemical
|
- 10. 6 phosphofructokinase
- [An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, C TYPE; found in platelets, brain, and other tissues. ( MSH )] (UMLS (CSP) C0031651) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;
| - 60. phosphocholine
- [magnesium and calcium salts used in hepatobiliary dysfunction therapy. ( CSP )] (UMLS (CSP) C0031716) =Organophosphorus Compound; Pharmacologic Substance ;
=phosphate;
|
- 11. 9-(2-phophonylmethoxyethyl)adenine
- [an adenine analog, antiviral agent; used for treating hepatitis, HIV and African swine fever virus infections. ( CSP )] (UMLS (CSP) C0050175) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =[AM800] ANTIVIRALS;
Reverse Transcriptase Inhibitor;
adenine analog;
Unclassified Ingredients =Adefovir Dipivoxil;
| - 61. phosphodiester
- [ ] (UMLS (CSP) C0599124) =Organophosphorus Compound
|
- 12. phobia
- [anxiety disorder characterized by intense, unrealistic, persistent fear and avoidance of an object, activity, or situation. ( CSP )] (UMLS (CSP) C0349231) =Mental or Behavioral Dysfunction =Anxiety Disorders;
=agoraphobia | - 62. Phosphodiesterase Inhibitor
- [any substance or agent which suppresses, prevents or opposes the actions or biosynthesis of phosphodiesterases. ( CSP )] (UMLS (NCI) C0031638) =Pharmacologic Substance =enzyme inhibitor;
esterase inhibitor |
- 13. Phobia of Driving
- (UMLS (NCI) C1112258) =Mental or Behavioral Dysfunction
| - 63. phosphoenol transphosphorylase
- [ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40. ( MSH )] (UMLS (CSP) C0034348) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;
|
- 14. phocine distemper virus
- [A species of MORBILLIVIRUS causing distemper in seals. ( MSH )] (UMLS (CSP) C0206537) =Virus ;
| - 64. phosphoester ligase
- [ ] (UMLS (CSP) C0597218) =Amino Acid, Peptide, or Protein; Enzyme =ligase;
|
- 15. Phocomelia
- (UMLS (NCI) C0031575) =Congenital Abnormality
| - 65. phosphogluconate dehydrogenase
- [An enzyme of the oxidoreductase class that catalyzes the reaction 6-phospho-D-gluconate and NADP+ to yield D-ribulose 5-phosphate, carbon dioxide, and NADPH. The reaction is a step in the pentose phosphate pathway of glucose metabolism. (From Dorland, 27th ed) EC 1.1.1.43. ( MSH )] (UMLS (CSP) C0031654) =Amino Acid, Peptide, or Protein; Enzyme =alcohol oxidoreductase;
|
- 16. Phocomelia of Lower Limb
- (UMLS (NCI) C0265625) =Congenital Abnormality ;
| - 66. phosphogluconate oxidative pathway
- [ ] (UMLS (CSP) C0599090) =Molecular Function
|
- 17. Phocomelia of the Upper Limb
- (UMLS (NCI) C0265573) =Congenital Abnormality ;
| - 67. phosphoglycerate kinase
- [An enzyme catalyzing the transfer of a phosphate group from 3-phospho-D-glycerate in the presence of ATP to yield 3-phospho-D-glyceroyl phosphate and ADP. EC 2.7.2.3. ( MSH )] (UMLS (CSP) C0031656) =Amino Acid, Peptide, or Protein; Enzyme =other phosphotransferase;
|
- 18. Phone
- (UMLS (HL7) C1547567) =Idea or Concept =Authorization Mode;
◊ (UMLS (HL7) C1548343) Intellectual Product Visit User Code; | - 68. phosphoglycerate mutase
- [An enzyme that catalyzes the conversion of 2-phospho-D-glycerate to 3-phospho-D-glycerate. EC 5.4.2.1. ( MSH )] (UMLS (CSP) C0031659) =Amino Acid, Peptide, or Protein; Enzyme =phosphomutase;
|
- 19. Phone
- (UMLS (HL7) C1548533) =Spatial Concept =Person location type;
| - 69. phosphohexisomerase
- [ ] (UMLS (CSP) C0599825) =Amino Acid, Peptide, or Protein; Enzyme
|
- 20. Phone
- [For attributes representing telephone number of a telecommunication device. See also COM. ( HL7V3.0 )] (UMLS (HL7) C1576870) =Idea or Concept =MDFAttributeType;
| - 70. Phosphoinositide-3-Kinase, Catalytic, Alpha Polypeptide Gene
- [This gene is involved in apoptosis, cell growth and angiogenesis. ( NCI )] (UMLS (NCI) C1335212) PIK3CA;
PIK3CA Gene =Gene or Genome ;
|
- 21. Phone
- [Electronic equipment that converts sound into electrical signals that can be transmitted over distances and then converts received signals back into sounds. ( NCI )] (UMLS (NCI) C0039457) =Manufactured Object ;
=Telecommunication equipment type;
| - 71. Phosphoinositide-3-Kinase, Catalytic, Beta Polypeptide Gene
- [This gene is involved in apoptosis, cell growth and angiogenesis. ( NCI )] (UMLS (NCI) C1335213) PIK3CB;
PIK3CB Gene =Gene or Genome ;
|
- 22. phonetic
- [A name spelled phonetically. There are a variety of phonetic spelling algorithms. This code value does not distinguish between these.Discussion: ( HL7V3.0 )] (UMLS (HL7) C1552604) =Intellectual Product =search;
| - 72. Phosphoinositide-3-Kinase, Catalytic, Gamma Polypeptide Gene
- [This gene is involved in cell adhesion, signal transduction and maintenance of the structural and functional integrity of epithelia. ( NCI )] (UMLS (NCI) C1335214) PIK3CG;
PIK3CG Gene =Gene or Genome ;
|
- 23. Phonetic (i.e., ASCII, Katakana, Hiragana, etc.)
- (UMLS (HL7) C1547502) =Idea or Concept =Name/address representation;
| - 73. Phosphoinositide-3-Kinase, Regulatory Subunit 3 (p55, Gamma) Gene
- [This gene plays a role in cell cycle regulation and hormonal signaling. ( NCI )] (UMLS (NCI) C1335215) PIK3R3;
PIK3R3 Gene =Gene or Genome ;
|
- 24. phonetics
- [The science or study of speech sounds and their production, transmission, and reception, and their analysis, classification, and transcription. (Random House Unabridged Dictionary, 2d ed) ( MSH )] (UMLS (CSP) C0031579) =Occupation or Discipline
| - 74. Phosphoinositol Kinase Family Gene
- [Human Phosphoinositol Kinase Family Genes encode Phosphoinositol Kinases, enzymes that phosphorylate at various positions the inositol group in membrane-bound phosphatidylinositol, often in response to extracellular signals through G-Protein Coupled Receptors or Receptor Tyrosine Kinases. The resultant phosphoinositides act as selective membrane docking sites for signal transduction proteins with diverse PH domains. Phosphorylated inositols are released as second messengers by enzymatic cleavage of the phosphoinositides. ( NCI )] (UMLS (NCI) C1335406) =Gene or Genome ;
|
- 25. phonoarthrography
- [ ] (UMLS (CSP) C0599424) =Diagnostic Procedure
| - 75. phospholamban
- [free sarcoplasmic reticulum polymeric proteolipid which modulates sarcoplasmic reticulum function; phosphorylated by cAMP-dependent, calcium-calmodulin-dependent, and calcium-phospholipid-dependent protein kinases. ( CSP )] (UMLS (CSP) C0070876) =Amino Acid, Peptide, or Protein; Enzyme =calcium binding protein;
|
- 26. PHONOCARDIOGRAM
- [ ] (UMLS (ICD9CM) C0199597) =Diagnostic Procedure
| - 76. Phospholine Iodide
- (UMLS (NCI) C0701977) =Organophosphorus Compound; Pharmacologic Substance
|
- 27. phonocardiography
- [Graphic registration of the heart sounds picked up as vibrations and transformed by a piezoelectric crystal microphone into a varying electrical output according to the stresses imposed by the sound waves. The electrical output is amplified by a stethograph amplifier and recorded by a device incorporated into the electrocardiograph or by a multichannel recording machine. ( MSH )] (UMLS (CSP) C0031580) =Diagnostic Procedure
| - 77. phospholipase A
- [Phospholipases that hydrolyze one of the acyl groups of phosphoglycerides or glycerophosphatidates. ( MSH )] (UMLS (CSP) C0031672) =Amino Acid, Peptide, or Protein; Enzyme
|
- 28. phonology
- [science which studies vocal sounds in language or a language with reference to their distribution and patterning and to tacit rules governing pronunciation. ( CSP )] (UMLS (CSP) C0597725) =Occupation or Discipline ;
=language;
| - 78. Phospholipase A2, Group IIA (Platelets, Synovial Fluid) Gene
- [This gene is involved in the regulation of the inflammatory response. ( NCI )] (UMLS (NCI) C1335221) PLA2G2A;
PLA2G2A Gene =Gene or Genome ;
|
- 29. phorbol
- [phorbol esters such as PMA and TPA are widely used as experimental tumor promotors; they act by directly stimulating protein kinase C, bypassing its normal calcium-based integration with other cellular processes. ( CSP )] (UMLS (CSP) C0031588) =Organic Chemical =diterpene;
Tumor Promoter | - 79. Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Gene
- [This gene plays a role in the regulation of the inflammatory response. ( NCI )] (UMLS (NCI) C1418620) PLA2G4A;
PLA2G4A Gene =Gene or Genome |
- 30. phorbol ester
- [Polycyclic compound isolated from croton oil in which two hydroxyl groups on neighboring carbon atoms are esterified to fatty acids. The commonest of these derivatives is phorbol myristoyl acetate (PMA). Potent co carcinogens or tumor promotors, they are diacyl glycerol analogs and activate protein kinase C irreversibly. ( NCI )] (UMLS (CSP) C0031586) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 80. Phospholipase A2, Group IVB (Cytosolic) Gene
- [This gene is involved in the initiation of the inflammatory response. ( NCI )] (UMLS (NCI) C1418621) PLA2G4B;
PLA2G4B Gene =Gene or Genome |
- 31. Phorbol-12-Myristate-13-Acetate-Induced Protein 1 Gene
- [This gene is a regulator of apoptosis through transcriptional activation. ( NCI )] (UMLS (NCI) C1321914) PMAIP1;
PMAIP1 Gene =Gene or Genome ;
| - 81. Phospholipase A2, Group IVC (Cytosolic, Calcium-Independent) Gene
- [This gene plays a role in the remodeling and maintenance of membrane components under altered cellular conditions such as oxidative stress. ( NCI )] (UMLS (NCI) C1418622) PLA2G4C;
PLA2G4C Gene =Gene or Genome |
- 32. Phormia
- [ ] (UMLS (CSP) C0323126) =Invertebrate
| - 82. Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) Gene
- [This gene plays a role in apoptosis and membrane remodeling. ( NCI )] (UMLS (NCI) C1418624) PLA2G6;
PLA2G6 Gene =Gene or Genome |
- 33. PHOS
- [A quantitative measurement of the amount of phosphate present in a sample. ( NCI )] (UMLS (NCI) C0523826) =Laboratory Procedure
| - 83. Phospholipase C, Beta 3 (Phosphatidylinositol-Specific) Gene
- [This gene is involved in the initiation of receptor-mediated signal transduction. ( NCI )] (UMLS (NCI) C1335225) PLCB3;
PLCB3 Gene =Gene or Genome ;
|
- 34. phosphamide
- [organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide. ( CSP )] (UMLS (CSP) C0012393) =Organophosphorus Compound; Pharmacologic Substance; Hazardous or Poisonous Substance =organophosphorus insecticide;
phosphorus compound =(-)-Cyclophosphamide;
2-oxo-N,3-bis-(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin- 2-amine;
| - 84. Phospholipase C, Gamma 2 (Phosphatidylinositol-Specific) Gene
- [This gene is involved in the generation of second messengers in the transmembrane signaling of ligand-activated growth factor receptors. ( NCI )] (UMLS (NCI) C1335226) PLCG2;
PLCG2 Gene =Gene or Genome |
- 35. phosphatase
- [a group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate. ( CSP )] (UMLS (CSP) C0031678) =Amino Acid, Peptide, or Protein; Enzyme =Ester Hydrolase;
=5' nucleotidase;
acid phosphatase;
alkaline phosphatase;
fructose biphosphatase;
glucose 6 phosphatase;
nucleotidase;
phosphatidate phosphatase;
phosphoprotein phosphatase;
phosphorylase phosphatase;
calcineurin;
Cytosolic Protein Tyrosine Phosphastase;
| - 85. phospholipase inhibitor
- [any substance or agent which suppresses, prevents or opposes the actions of phospholipases. ( CSP )] (UMLS (CSP) C0597220) =Pharmacologic Substance ;
=enzyme inhibitor;
|
- 36. Phosphatase and Tensin Homolog (Mutated in Multiple Advanced Cancers 1) Gene
- [This gene plays a role in signal transduction and apoptosis. It is also involved in the regulation of cell cycle progression. ( NCI )] (UMLS (NCI) C0694888) =Gene or Genome ;
| - 86. Phospholipid Binding
- [Phospholipid Interaction involves temporary non-covalent binding of a molecule through intermolecular physical forces of attraction with a member of a heterogeneous group of water-insoluble aliphatic hydrocarbons that contain phosphorus (phosphoglycerides, plasmalogens, or sphingomyelins), the major form of lipid in cell membranes. ( NCI )] (UMLS (NCI) C1148642) =Molecular Function ;
|
- 37. Phosphatase Family Gene
- [Phosphotransferase Genes encode Phosphotransferases (Phosphatases), a large group of enzymes subdivided according to acceptor group that transfer phosphate, diphosphate, nucleotidyl residues, and other phosphomoieties. Some phosphotransferases catalyze the conversion of a proenzyme to an active enzyme; others transfer phosphate groups to form triphosphates (e.g., ATP). (NCI) ( NCI )] (UMLS (NCI) C1335403) =Gene or Genome ;
| - 87. phospholipid inhibitor
- [any substance or agent which suppresses, prevents or opposes the actions of phospholipids. ( CSP )] (UMLS (CSP) C0597221) =Pharmacologic Substance ;
=inhibitor/antagonist;
|
- 38. phosphatase inhibitor
- [any substance or agent which suppresses, prevents or opposes the action of the hydrolase class of enzymes that are phosphoric monoester hydrolases which catalyzing the release of inorganic phosphate from phosphoric esters. ( CSP )] (UMLS (CSP) C0597217) =Pharmacologic Substance ;
=enzyme inhibitor;
=OKA | - 88. Phospholipid Metabolism
- [Phospholipid Metabolism involves anabolic and catabolic biochemical changes made to the heterogeneous class of phosphate derivative hydrophobic aliphatic hydrocarbons within a cell needed for important life processes and a major form of lipid in all cell membranes. ( NCI )] (UMLS (NCI) C1158419) =Molecular Function
|
- 39. phosphate
- [PO4(3-). ( CSP )] (UMLS (CSP) C1601799) =Inorganic Chemical ;
=phosphorus compound;
=calcium phosphate;
phosphoric ester;
phosphocholine;
polyphosphate;
diphosphate;
alkylphosphate | - 89. phosphomonoester
- [ ] (UMLS (CSP) C0599125) =Organophosphorus Compound
|
- 40. phosphate absorption inhibitor
- [ ] (UMLS (CSP) C0598693) =Pharmacologic Substance
| - 90. phosphomutase
- [A group of enzymes that catalyze an intramolecular transfer of a phosphate group. It has been shown in some cases that the enzyme has a functional phosphate group, which can act as the donor. These were previously listed under PHOSPHOTRANSFERASES (EC 2.7.-). (From Enzyme Nomenclature, 1992) EC 5.4.2. ( MSH )] (UMLS (CSP) C0206356) =Amino Acid, Peptide, or Protein; Enzyme ;
=isomerase;
=glucose phosphomutase;
phosphoglycerate mutase |
- 41. Phosphate Buffer
- [A chemical reagent containing at least any one of the many phosphoric acid derivatives, usually in salt form. The phosphoric salt may be one of three types: strongly acid monometallic, neutral or mildly alkaline dimetallic, and strongly alkaline tri-metallic. Phosphate buffers are typically adjusted to maintain a certain pH or are "buffered" with other chemical compounds. Phosphate reagents are used in research laboratories, medicine or industry in various technical procedures. (NCI04) ( NCI )] (UMLS (NCI) C0991865) PHOSPHATE BUFFERS;
PHOSPHATE BUFFERS PREPARATION;
=Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid =inorganic phosphate;
Unclassified Ingredient Preparations =xylometazoline 1 MG/ML Nasal Solution;
CONTACT LENS DISINFECTING (OXYSEPT 1) SOLN;
| - 91. phosphonate
- [H2PO3-. ( CSP )] (UMLS (CSP) C0260127) =Chemical Viewed Structurally ;
=phosphorus compound;
=biphosphonate;
foscarnet;
aminophosphonate |
- 42. phosphate diabetes
- [ ] (UMLS (CSP) C0282201) =Disease or Syndrome ;
| - 92. phosphonium compound
- [ ] (UMLS (CSP) C0597222) =Inorganic Chemical
|
- 43. phosphate ester
- [ ] (UMLS (CSP) C0599126) =Organophosphorus Compound
| - 93. phosphonoformate
- [ ] (UMLS (CSP) C0376236) =Organophosphorus Compound; Pharmacologic Substance ;
|
- 44. phosphatidate
- [fatty acid derivatives of glycerophosphates; composed of glycerol bound in ester linkage with 1 mole of phosphoric acid at the terminal 3-hydroxyl group and with 2 moles of fatty acids at the other two hydroxyl groups. ( CSP )] (UMLS (CSP) C0178797) =Lipid =Glycerophospholipids;
| - 94. phosphonous acid
- [ ] (UMLS (CSP) C0031683) =Chemical Viewed Structurally ;
|
- 45. phosphatidate phosphatase
- [A phosphomonoesterase involved in the synthesis of triacylglycerols. It catalyzes the hydrolysis of phosphatidates with the formation of diacylglycerols and orthophosphate. EC 3.1.3.4. ( MSH )] (UMLS (CSP) C0031607) =Amino Acid, Peptide, or Protein; Enzyme ;
=phosphatase;
| - 95. phosphonylmethoxypropyl adenine
- [ ] (UMLS (CSP) C0872244) =Organophosphorus Compound; Pharmacologic Substance ;
|
- 46. phosphatide
- [any lipid that contains phosphorus, including those with a glycerol backbone or a backbone of sphingosine or related substance; these polar lipids are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids. ( CSP )] (UMLS (CSP) C0031676) =Lipid; Biologically Active Substance =lipid;
membrane lipid;
phosphorus compound;
Inactive Ingredient Preparations =lysophospholipid;
plasmalogen;
Glycerophospholipids;
glycerophosphate;
Lung Surfactant;
BASLE CREAM,TOP | - 96. phosphopeptide
- [ ] (UMLS (CSP) C0031684) =Amino Acid, Peptide, or Protein ;
=Peptides;
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- 47. Phosphatidic Acid Phosphatase Type 2A Gene
- [This gene is involved in lipid metabolism/transport and receptor-activated signal transduction. ( NCI )] (UMLS (NCI) C1335236) PPAP2A;
PPAP2A Gene =Gene or Genome | - 97. Phosphoprotein
- [protein phosphorylation is probably the most ubiquitous and diverse molecular mechanism of biological signal transduction; thus many proteins (not all treed here) may be phosphorylated at some time. ( CSP )] (UMLS (NCI) C0031689) =Amino Acid, Peptide, or Protein; Biologically Active Substance
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- 48. Phosphatidylcholine Biosynthesis
- [The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase is the initial enzyme that produces phosphocholine from choline in the sequence and may play a regulatory role. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1157380) =Molecular Function
| - 98. phosphoprotein phosphatase
- [family of enzymes which dephosphorylate other proteins, thus reversing the action of protein kinases in posttranslational regulation of protein function. ( CSP )] (UMLS (CSP) C0031686) =Amino Acid, Peptide, or Protein; Enzyme =phosphatase;
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- 49. phosphatidylethanolamine
- [derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to an ethanolamine moiety. ( CSP )] (UMLS (CSP) C0031618) =Lipid; Pharmacologic Substance; Biologically Active Substance =Glycerophospholipids;
| - 99. Phosphoramide Mustard
- [One of a number of chemically-related alkylating agents with antineoplastic properties. The prototype of this group of agents is cyclophosphamide. Most phosphoramide mustards are administered as prodrugs that undergo reductive activation in hypoxic environments to yield cytotoxic metabolites. These agents alkylate and crosslink DNA, resulting in inhibition of DNA replication. Phosphoramide mustards are also immunosuppressants, mutagens and teratogens. (NCI04) ( NCI )] (UMLS (NCI) C0070913) =Organophosphorus Compound ;
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- 50. phosphatidylglycerol
- [ ] (UMLS (CSP) C0031614) =Lipid; Biologically Active Substance ;
| - 100. phosphorescence
- [absorption of a photon of light followed, after a delay, by emission of a photon of a longer wavelength; the difference in wavelengths is greater for phosphorescence than fluorescence. ( CSP )] (UMLS (CSP) C0031694) =Natural Phenomenon or Process
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