- 1. (R)-1-Methyl-4-(1-methylethenyl)cyclohexene
- [The dextro isomer of limonene, a natural cyclic monoterpene and major component of the oil extracted from citrus rind with chemo-preventive and antitumor activities. The metabolites of D-limonene, perillic acid, dihydroperillic acid, uroterpenol and limonene 1,2-diol are suggested to inhibit tumor growth through inhibition of p21-dependent signaling, induce apoptosis via the induction of the transforming growth factor beta-signaling pathway, inhibit post-translational modification of signal transduction proteins, result in G1 cell cycle arrest as well as cause differential expression of cell cycle- and apoptosis-related genes. ( NCI )] (UMLS (NCI) C0950252) 1-methyl-4-isopropenyl-1-cyclohexene;
D-Limonene;
LIMONENE, D-;
=Organic Chemical ;
| - 4. RMI-71782
- (UMLS (NCI) C0949215) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
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- 2. 3-[[(R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]indole, Monohydrobromide
- [A triptan with specific affinity for the 5-hydroxytriptamine1B/1D receptor. Eletriptan hydrobromide binds to and acts at serotonin 5-HT1B receptors located on intracranial blood vessels which leads to vasoconstriction. This drug may also exerts its effects by binding to and activating 5-HT 1D receptors on sensory nerve endings in the trigeminal system, which results in the inhibition of pro-inflammatory neuropeptide release. Eletriptan hydrobromide is used to relieve pain or symptoms associated with migraine headaches. ( NCI )] (UMLS (NCI) C1178489) ELETRIPTAN HYDROBROMIDE;
ELETRIPTAN HYDROBROMIDE UNIDENTIFIED =Organic Chemical; Pharmacologic Substance | - 5. RMIM identifier
- [Always the first row of the table, identifies the particular Refined Message Information Model in the nomenclature of the HL7 Repository ( HL7V3.0 )] (UMLS (HL7) C1554113) =Idea or Concept =MdfRmimRowType;
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- 3. R01 Mechanism
- [A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. ( NCI )] (UMLS (NCI) C0260206) =Research Activity ;
| - 6. [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid
- [A drug that is being studied as a treatment for cancer. It belongs to the family of drugs called dipeptidyl boronic acids. Also called PS-341. ( NCI )] (UMLS (NCI) C1176309) BORTEZOMIB;
BORTEZOMIB PREPARATION =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
Unclassified Ingredients =BORTEZOMIB 3.5 MG |
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