UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
R R R- R0 R1 R2 R3 R4 RA RB RC RD RE RF RG RH RI RK RM RN RO RP RQ RR RS RT RU RV RW RX RY
RS RS RS- RSB RSC RSE RSH RSN RSP RSR RSS RSV
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1. Rsc8
[A subunit of unknown function in the fifteen-protein RSC nucleosome/chromatin remodeling complex, Rsc8/Swh3 is a homolog of the SWI/SNF protein SWI3. Swi3/BAF155 contains a leucine zipper motif typical of many transcription factors. Swh3p undergoes dimerization via the coiled-coil C-terminus, forms a complex with RSC6p, interacts with the SWI2/SNF2 ATPase Sth1p, and appears to mediate multiple RSC interactions. SWI/SNF and RSC share conserved components. SWI/SNF proteins display helicase and ATPase activities and appear to regulate gene transcription by altering local chromatin structure. RSC complex is required for transcriptional regulation and nucleosome positioning. RSC maintains a repressive chromatin structure at certain inducible promoters. (from SGD; NAR 26:3739, 1998; EMBO J. 18:2836, 1999; and NCI) ( NCI )] (UMLS (NCI) C1455624) Rsc8/Swh3;
Swh3;
Swh3p;
YFR037C =Amino Acid, Peptide, or Protein; Biologically Active Substance ;

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