- 1. TIAGABINE
- (UMLS (NCI) C0068897) =Organic Chemical; Pharmacologic Substance =[CN400] ANTICONVULSANTS;
Nipecotic Acids =(-)-(R)-1-(4,4-Bis(3-methyl-2-thienyl)-3-butenyl)nipecotic Acid, Hydrochloride;
| - 2. TIAM1
- [TIAM1 appears to function in cellular signaling by modulating activation the GDP-GTP exchange activity of RHO-like GTPases that regulate cytoskeletal organization. The serine-rich TIAM1 protein contains a DH domain, a PDZ/DHR domain, and two PH domains. The DH domain is found in GDP-GTP exchanger proteins that activate RHO-like GTPases and PH domains are thought to be involved in protein-protein interactions. TIAM1 activates RAC1, CDC42, and to a lesser extent RHOA. (from OMIM 600687 and NCI) ( NCI )] (UMLS (NCI) C0919491) TIAM1 Protein;
T-Lymphoma Invasion and Metastatis Inducing Protein 1;
=Amino Acid, Peptide, or Protein; Biologically Active Substance |
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