- 101. 2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium Phosphate
- [A class Ia antiarrhythmic agent with cardiac depressant properties. Disopyramide phosphate exerts its actions by blocking both sodium and potassium channels in cardiac membrane during phase 0 of the action potential. This slows the impulse conduction through the AV node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues. Disopyramide prolongs the QT interval and causes a widening of the QRS complex. It also posesses some anticholinergic and local anaesthetic properties. Disopyramide phosphate is used in the treatment of supraventricular tachycardia. ( NCI )] (UMLS (NCI) C0700534) =Organic Chemical; Pharmacologic Substance =disopyramide;
=DISOPYRAMIDE PHOSPHATE 100 MG;
DISOPYRAMIDE PHOSPHATE 150 MG;
| - 151. 3-Amino-1-[4-(2 amino-1H-imidazolyl]-propanol, 2HCl
- [A compound isolated from the marine sponge Pseudaxinyssa cantharella exhibiting anti-tumor activity. Studies indicate girodazole acts during the elongation/termination steps of protein synthesis, resulting in protein synthesis inhibition. (NCI) ( NCI )] (UMLS (NCI) C0119196) =Organic Chemical; Pharmacologic Substance
|
- 102. 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
- (UMLS (NCI) C0380453) =Organic Chemical; Pharmacologic Substance ;
| - 152. 3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone
- [3-aminopyridine-2-carboxaldehyde thiosemicarbazone. A substance that is being studied as an anticancer drug. It belongs to the family of drugs called ribonucleotide reductase inhibitors. ( NCI )] (UMLS (NCI) C0210403) =Organic Chemical; Pharmacologic Substance ;
|
- 103. 2-(Acetyloxy)benzoic Acid
- [prototypical analgesic used in the treatment of mild to moderate pain; has antiinflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins; aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. ( CSP )] (UMLS (NCI) C0004057) =Organic Chemical; Pharmacologic Substance
| - 153. 3-AP/Cisplatin/Paclitaxel
- (UMLS (NCI) C0935830) =Therapeutic or Preventive Procedure
|
- 104. 2-AAF
- [A synthetic, light tan crystalline solid that is insoluble in water and soluble in alcohols, glycols, ether, acetic acid, and fat solvents. It is used as a positive control by toxicologists to study the carcinogenicity and mutagenicity of aromatic amines. When heated to decomposition, 2-acetylaminofluorene emits toxic fumes of nitrogen oxides. The primary routes of potential human exposure to 2-acetylaminofluorene are inhalation and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000248) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid; Hazardous or Poisonous Substance
| - 154. 3.Alpha,4.Beta, 15-triol, 12, 13-epoxy-,4, 15-diacetate (8CI)
- [trichothecene mycotoxin produced by species of Fusarium that contaminate grain and other foodstuffs, causing fusariotoxicosis and hemorrhaging in livestock. ( CSP )] (UMLS (NCI) C0057671) =Organic Chemical; Pharmacologic Substance ;
=Fungal Toxin;
sesquiterpene |
- 105. 2-Acetoxyethyltrimethylammonium Chloride
- [The chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride mimics the parasympathomimetic effect of the endogenous compound acetylcholine. Administered as an ophthalmic solution, this drug stimulates the cholinoceptors in the sphincter muscle of the iris, causing the pupil to constrict. (NCI05) ( NCI )] (UMLS (NCI) C0055389) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =acetylcholine;
=ACETYLCHOLINE CHLORIDE 1 %;
| - 155. 30a
- [Mandibular right first molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553668) =Medical Device =Artificial dentition;
|
- 106. 2-Amino 6MP
- [thioguanine is USP. ( CSP )] (UMLS (NCI) C0039902) =Organic Chemical; Pharmacologic Substance ;
=1,7-Dihydro-6H-purine-6-thione;
[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
purine;
guanine analog;
=THIOGUANINE 40 MG | - 156. 30ad
- [Mandibular right first molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553670) =Medical Device =Artificial dentition;
|
- 107. 2-Amino, 6-Methoxypurine Arabinoside
- [An arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0907349) 2-Amino-6-methoxypurine arabinoside;
2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine;
NELARABINE;
Nelarabine Intravenous Injection =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 157. 30am
- [Mandibular right first molar abutment mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1553669) =Medical Device =Artificial dentition;
|
- 108. 2-Amino-1,3-Dihydroxyoctadecane
- [A saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), L-threo-dihydrosphingosine competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41910&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41910&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1568" NCI Thesaurus) ( PDQ )] (UMLS (NCI) C0074987) =Lipid; Pharmacologic Substance ;
| - 158. 31a
- [Mandibular right second molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553671) =Medical Device =Artificial dentition;
|
- 109. 2-Amino-1,7-dihydro-6H-purin-6-one
- [2-amino-6-hydroxypurine; one of the 5 major bases (with adenine, thymine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0018321) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance =2-Aminopurine;
Hypoxanthines;
nucleobase;
=2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one | - 159. 31ad
- [Mandibular right second molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553673) =Medical Device =Artificial dentition;
|
- 110. 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
- [9-(2-hydroxyethoxymethyl) guanine; acts against herpesviruses by inhibiting the viral DNA polymerase. ( CSP )] (UMLS (NCI) C0001367) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 160. 31am
- [Mandibular right second molar abutment mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1553672) =Medical Device =Artificial dentition;
|
- 111. 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one
- [9-(1,3-dihydroxy-2-propoxy)methylguanine; acyclovir analog which inhibits DNA replication of CMV and therefore has efficacy against AIDS-related oculopathy. ( CSP )] (UMLS (NCI) C0017066) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one;
[AM800] ANTIVIRALS;
2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one;
[OP203] ANTIVIRALS, TOPICAL OPHTHALMIC;
nucleoside analog;
=2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one;
DHPG sodium;
GANCICLOVIR 500 MG;
GANCICLOVIR 4.5 MG;
| - 161. 32a
- [Mandibular right third molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553674) =Medical Device =Artificial dentition;
|
- 112. 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine
- [A synthetic, gray-white crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045811) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 162. 32ad
- [Mandibular right third molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553676) =Medical Device =Artificial dentition;
|
- 113. 2-Amino-3,4-Dimethylimidazole[4,5-f]quinoline
- [A synthetic, yellow-green crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). 2-Amino-3-methylimidazo[4,5-f]quinoline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045819) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 163. 32am
- [Mandibular right third molar abutment mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1553675) =Medical Device =Artificial dentition;
|
- 114. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline
- [A synthetic, pale orange to brown crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045822) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 164. 3a
- [Maxillary right first molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553635) =Medical Device =Artificial dentition;
|
- 115. 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic Acid
- [precursor of serotonin used as antiepileptic and antidepressant. ( CSP )] (UMLS (NCI) C0000578) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
| - 165. 3AP/FAMP
- [A combination of the thiosemicarbazone 3-aminopyridine-2-carboxaldehyde (3-AP) and the nucleoside analogue fludarabine with antineoplastic activity. The agents in 3-AP/fludarabine, act synergistically to inhibit the enzyme ribonucleotide reductase.. Composed of two subunits, this enzyme catalyzes the rate-limiting step in the conversion of ribonucleotides to deoxyribonucleotides. The 3-AP binds to and inactivates one subunit while fludarabine binds to and inactivates the other. Fludarabine also inhibits DNA polymerase alpha and DNA primase. At low concentrations, this agent arrests tumor cells in the S-phase of the cell cycle; at higher concentrations, in the G0/G1 phase of the cell cycle. (NCI04) ( NCI )] (UMLS (NCI) C1328164) 3-AP/Fludarabine =Therapeutic or Preventive Procedure; ;
|
- 116. 2-Amino-3-hydroxypropionic Acid
- [naturally occurring nonessential aminoacid, chemical name 2-amino-3-hydroxypropionic acid; it may be synthesized from glycine or threonine and is involved in the biosynthesis of purines, pyrimidines, and other amino acids. ( CSP )] (UMLS (NCI) C0036720) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =Amino Acids, Neutral;
hydroxyaminoacid;
primary aminoacid;
Inactive Ingredient Preparations;
Unclassified Ingredient Preparations;
=(+)-4-Amino-3-isoxazolidinone;
SERINE 0.33 GM;
SERINE 0.5 GM;
SERINE 1.86 MG/ML;
SERINE 147 MG/100ML;
SERINE 150 MG/100ML;
SERINE 180 MG;
SERINE 2.21 MG/ML;
SERINE 2.25 MG/ML;
SERINE 2.65 MG/ML;
SERINE 20 MG;
SERINE 210 MG/100ML;
SERINE 230 MG/100ML;
SERINE 3 MG/ML;
SERINE 3.7 MG/ML;
SERINE 3.71 MG/ML;
SERINE 300 MG;
SERINE 347 MG/100ML;
SERINE 370 MG;
SERINE 4.5 MG/ML;
SERINE 4.95 MG/ML;
SERINE 420 MG/100ML;
SERINE 5 MG;
SERINE 5.3 MG/ML;
SERINE 5.92 MG/ML;
SERINE 500 MG;
SERINE 500 MG/100ML;
SERINE 56 MG/GM;
SERINE 590 MG/100ML;
SERINE 795 MG/100ML | - 166. 4 aminosalicylic acid
- [antitubercular agent often administered in association with isoniazid. ( CSP )] (UMLS (CSP) C0030125) =Organic Chemical; Pharmacologic Substance ;
=antitubercular agent;
salicylate |
- 117. 2-Amino-3-methylimidazo[4,5-f]quinoline
- [A synthetic, light tan crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3-methylimidazo[4,5-f]quinoline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). 2-Amino-3-methylimidazo[4,5-f]quinoline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C1312059) 3-Methyl-3H-imidazo[4,5-f]quinolin-2-amine;
IQ =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance | - 167. 4'-(9-Acridinylamino)methane-sulfon-m-anisidide
- [An anticancer drug that belongs to the family of drugs called topoisomerase inhibitors. ( NCI )] (UMLS (NCI) C0002699) =Organic Chemical; Pharmacologic Substance ;
|
- 118. 2-Amino-4-(S-butylsulfonimidoyl) Butanoic Acid
- [used as a thiol depleter and inhibitor of the enzyme gamma glutamylcysteine synthase. ( CSP )] (UMLS (NCI) C0054252) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hazardous or Poisonous Substance =Amino Acids, Sulfur;
sulfhydryl reagent | - 168. 4'-Amino-6-hydroxyflavone
- [A compound that inhibits the Protein-Tyrosine Kinase Activity of p56lck. ( NCI )] (UMLS (NCI) C0644340) =Organic Chemical; Pharmacologic Substance
|
- 119. 2-Amino-5-(carbamoylamino)pentanoic Acid
- [amino acid, C6H13N3O3, originally isolated from watermelon, that is produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver; chemical name L-ornithine, N5-(aminocarbonyl). ( CSP )] (UMLS (NCI) C0008864) =Amino Acid, Peptide, or Protein; Biologically Active Substance =aa;
| - 169. 4,5-alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one Hydrochloride
- [The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. ( NCI )] (UMLS (NCI) C0282275) =Organic Chemical; Pharmacologic Substance =OXYMORPHONE;
=OXYMORPHONE HYDROCHLORIDE 1 MG/ML;
OXYMORPHONE HYDROCHLORIDE 1.5 MG/ML;
OXYMORPHONE HYDROCHLORIDE 5 MG |
- 120. 2-amino-5-bromo-6-phenyl-4-(3H)-pyrimidinone
- [An oral immunostimulant that causes the body to produce interferon and other substances. ( NCI )] (UMLS (NCI) C0054150) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 170. 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride
- [The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism. ( NCI )] (UMLS (NCI) C0282274) =Organic Chemical; Pharmacologic Substance =4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one;
=OXYCODONE HYDROCHLORIDE 5 MG;
OXYCODONE HYDROCHLORIDE 20 MG/ML;
OXYCODONE HYDROCHLORIDE 5 MG/5ML;
OXYCODONE HYDROCHLORIDE 20 MG;
OXYCODONE HYDROCHLORIDE 80 MG;
OXYCODONE HYDROCHLORIDE 160 MG;
OXYCODONE HYDROCHLORIDE 10 MG;
OXYCODONE HYDROCHLORIDE 40 MG;
OXYCODONE HYDROCHLORIDE 15 MG;
OXYCODONE HYDROCHLORIDE 2.5 MG;
OXYCODONE HYDROCHLORIDE 7.5 MG;
OXYCODONE HYDROCHLORIDE 30 MG;
OXYCODONE HYDROCHLORIDE 2.25 MG;
OXYCODONE HYDROCHLORIDE 4.5 MG;
|
- 121. 2-Amino-5-chlorotoluene
- [A yellowish to pinkish colored, synthetic leaflet material. p-Chloro-o-toluidine is used in industry in the manufacture of azo dyes and is used in the production of the pesticide chlordimeform. This substance is a possible mutagen and is reasonably anticipated to be a human carcinogen that may be associated with an increased risk of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0048164) =Organic Chemical; Pharmacologic Substance
| - 171. 4-(Acetylamino)-N-(2-aminophenyl)benzamide
- [A substance that is being studied as an anticancer drug in the treatment of non-small cell lung cancer. Also called N-acetyldinaline. ( NCI )] (UMLS (NCI) C0217598) =Organic Chemical; Pharmacologic Substance ;
|
- 122. 2-Amino-6-(trifluoromethoxy)benzothiazole
- [A benzathiozole derivative with neuroprotective property. Although the mechanism of action has not been fully elucidated, riluzole may protect neural tissue by inhibiting glutamate release from presynaptic endings in the central nervous system. The agent also blocks postsynaptic NMDA-kainate-type glutamate receptors and inhibits voltage-dependent sodium channels. The inhibition of glutamatergic neurotransmission results in muscle relaxation and sedative effects. ( NCI )] (UMLS (NCI) C0073379) =Organic Chemical; Pharmacologic Substance ;
=thiazole;
[CN900] CNS MEDICATIONS, OTHER =RILUZOLE 50 MG | - 172. 4-(all-trans-retino-yl)aminophenol
- [N-(4-hydroxyphenyl)retinamide; a synthetic retinoid used orally as a chemopreventive agent against prostate cancer in men and in women at risk of developing breast cancer; also effective as an antineoplastic agent. ( CSP )] (UMLS (NCI) C0060197) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
Retinoic Acid Agent |
- 123. 2-Amino-9,10-anthracenedione
- [A synthetic, red or orange-brown needle-shaped solid that is insoluble in water and soluble in alcohol, acetone, benzene and chloroform. It is used as intermediate for the synthesis of both anthraquinone dyes and pharmaceutical products. When 2-aminoanthraquinone is heated to decomposition, it emits toxic fumes of nitrogen oxides. The primary route of potential human exposure to this chemical is dermal contact. Acute exposure of humans to 2-aminoanthraquinone can cause irritation of the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045870) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 173. 4-(Aminomethyl)benzenesulfonamide Monoacetate
- [The acetate salt form of mafenide, a synthetic sulfonamide analog of para-aminobenzoic acid (PABA) with topical anti-infective activity. Mafenide acetate competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, thereby interferes with normal folic acid metabolism. As a result de novo synthesis of pyrimidines, which requires folate metabolites, is impeded and subsequently DNA synthesis is affected. Mafenide acetate is bacteriostatic against many gram-negative and gram-positive organisms, including Pseudomonas aeruginosa and certain strains of anaerobes. ( NCI )] (UMLS (NCI) C0024453) =Organic Chemical; Pharmacologic Substance =MAFENIDE;
[DE101] ANTIBACTERIAL, TOPICAL =MAFENIDE ACETATE 8.5 %;
MAFENIDE ACETATE 50 GM;
|
- 124. 2-Aminonaphthalene
- [A synthetic, air-sensitive, colorless crystalline solid that is soluble in hot water, alcohol, ether and many organic solvents. Currently, it is only used in laboratory research. Because the commercial production and use of 2-naphthylamine are banned, the potential for human exposure is low. The general population may be exposed to this chemical through inhalation of emissions from sources where nitrogen-containing organic matter is burned, such as coal furnaces and cigarettes. At greatest risk of occupational exposure to 2-naphthylamine are laboratory technicians and scientists who use it in research. Acute inhalation exposure to high levels of 2-naphthylamine can result in methemoglobinemia, dyspnea, ataxia, hematuria, dysuria and hemorrhagic cystitis. It is known to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000300) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 174. 4-Acridinecarboxamide,9-((2-methoxy-4-((methylsulfonyl)amino)phenyl)amino-N,5-dimethyl
- (UMLS (NCI) C0130561) =Organic Chemical; Pharmacologic Substance ;
|
- 125. 2-Aminotoluene
- [A synthetic, light sensitive, light yellow liquid that is slightly soluble in water and miscible with carbon tetrachloride, diethyl ether and ethanol. The hydrochloride is a synthetic, light sensitive, white crystalline powder that is soluble in dimethylsulfoxide and ethanol. o-Toluidine and o-toluidine hydrochloride are used primarily as intermediates in the manufacture of dyes and pigments. When heated to decomposition, o-toluidine emits toxic fumes of nitrogen oxides while the hydrochloride also produces hydrochloric acid. Four studies of workers exposed to o-toluidine reported an excess of bladder cancers. o-Toluidine and o-toluidine hydrochloride are reasonably anticipated to be human carcinogens. (NCI05) ( NCI )] (UMLS (NCI) C0046584) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
| - 175. 4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
- [pyrimidine analog that inhibits DNA methyltransferase, impairing DNA methylation, also an antimetabolite of cytidine, incorporated primarily into RNA; has been used as an antineoplastic agent. ( CSP )] (UMLS (NCI) C0004475) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 126. 2-Aza-8-germaspiro[4.5]decane-2-propanamine, 8, 8-diethyl-N,N-dimethyl-, dihydrochloride
- (UMLS (NCI) C0954126) Spirogermanium HCl;
Spirogermanium hydrochloride =Organic Chemical; Pharmacologic Substance | - 176. 4-Amino-10-methylfolic Acid
- [folic acid antagonist that acts by inhibiting the synthesis of nucleic acids, thymidylate, and protein; used as an antineoplastic in a wide variety of malignancies, and as an antipsoriatic and antirheumatic. ( CSP )] (UMLS (NCI) C0025677) =Organic Chemical; Pharmacologic Substance ;
=4-Aminofolic acid;
[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
antifolate;
pteridine;
=METHOTREXATE SODIUM |
- 127. 2-Aziridinecarboxamide, 1-[1-(2-cyano-1-aziridinyl)-1-methylethyl]
- [Azimexon (2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane) is a derivative of 2-cyanaziridine. Immunostimulant which shows therapeutic effects in tumor models and experimental infections in vitro, enhancing T lymphocyte transformation and phagocytosis. The mode of action of azimexon is unknown. It has been suggested that azimexon may alkylate DNA. In cancer patients it increases leukocytosis, blood active T rosettes, T4/T8 ratio, and is used as an adjuvant to chemotherapy in the treatment of melanoma and myeloma. ( NCI )] (UMLS (NCI) C0104835) =Organic Chemical; Pharmacologic Substance ;
| - 177. 4-Amino-2(1H)-pyrimidinone
- [2-keto-4-aminopyrimidine, one of the 5 major bases (with adenine, guanine, uracil, and thymine) which are a component of nucleic acids. ( CSP )] (UMLS (NCI) C0010843) =Organic Chemical; Biologically Active Substance =Pyrimidinones;
aminopyrimidine;
nucleobase;
=4-Amino-5-fluoro-2(1H)-pyrimidinone;
1(3-hydroxy-2-phosphonomethoxypropyl) Cytosine |
- 128. 2-[(Aminocarbonyl)oxy]-N,N,N-trimethyl-1-propanaminium Chloride
- [A synthetic quaternary ammonium base derivative, parasympathomimetic Bethanechol is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Generally used to increase smooth muscle tone, Bethanechol is used to treat reflux esophagitis and to initiate urination after surgery, in urinary infections, or for enlarged prostate. It may cause hypotension, cardiac rate changes, and bronchial spasms. (NCI04) ( NCI )] (UMLS (NCI) C0106169) =Organic Chemical; Pharmacologic Substance =bethanechol;
=BETHANECHOL CHLORIDE 25 MG;
BETHANECHOL CHLORIDE 10 MG;
BETHANECHOL CHLORIDE 50 MG;
BETHANECHOL CHLORIDE 5 MG;
| - 178. 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
- [An imidazoquinolinamine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activates other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans' cells leading to an enhanced activation of T-lymphocytes. Due to its immunostimulatory activity, this agent may potentially be useful as a vaccine adjuvant. ( NCI )] (UMLS (NCI) C0965594) Resiquimod =Organic Chemical; Pharmacologic Substance ;
|
- 129. 20a
- [Mandibular left second premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553658) =Medical Device =Artificial dentition;
| - 179. 4-Amino-3-(4-chlorophenyl)-butanoic Acid
- [A synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors. It acts at spinal and supraspinal sites, reducing excitatory transmission. (NCI04) ( NCI )] (UMLS (NCI) C0004609) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 130. 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione
- [The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. ( NCI )] (UMLS (NCI) C0056391) =Steroid; Pharmacologic Substance; Hormone =17,21-Dihydroxypregn-4-ene-3,11,20-trione;
=CORTISONE ACETATE 25 MG;
CORTISONE ACETATE 50 MG/ML;
CORTISONE ACETATE 5 MG;
CORTISONE ACETATE 10 MG;
| - 180. 4-Amino-3-[[4'-((2,4-Diaminophenyl)azo)(1,1'-Biphenyl)-4-yl]azo]-5-Hydroxy-6-(Phenylazo)- 2,7-Naphthalenedisulfonic Acid, Disodium Salt
- [A Benzidine-based azo dye that is metabolized to free Benzidine in vivo. Direct black 38 is primarily used for the dyeing of textiles, leather and paper. Benzidine and its metabolic derivatives have been detected in the urine of workers exposed to Benzidine-based dyes. Exposure to this dye is strongly associated with the occurrence of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0058437) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
|
- 131. 21a
- [Mandibular left first premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553659) =Medical Device =Artificial dentition;
| - 181. 4-Amino-5-fluoro-2(1H)-pyrimidinone
- [fluorinated cytosine analog that is used as an antifungal agent. ( CSP )] (UMLS (NCI) C0016278) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM700] ANTIFUNGALS;
4-Amino-2(1H)-pyrimidinone;
pyrimidine analog;
halocarbon compound =FLUCYTOSINE 250 MG;
FLUCYTOSINE 500 MG;
|
- 132. 22a
- [Mandibular left canine abutment ( HL7V3.0 )] (UMLS (HL7) C1553660) =Medical Device =Artificial dentition;
| - 182. 4-Amino-7.beta.-D-ribofuranosyl-7H-pyrrolo(2, 3-d)pyrimidine
- [antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids; an antineoplastic antimetabolite. ( CSP )] (UMLS (NCI) C0041286) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=antifungal antibiotic;
antineoplastic antibiotics;
antitubercular agent;
ribonucleoside;
nucleoside analog;
|
- 133. 23a
- [Mandibular left lateral incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553661) =Medical Device =Artificial dentition;
| - 183. 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide
- [A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death. ( NCI )] (UMLS (NCI) C0038745) =Organic Chemical; Pharmacologic Substance ;
=Sulfanilamides;
[AM650] SULFONAMIDE/RELATED ANTIMICROBIALS =SULFISOXAZOLE DIOLAMINE;
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-;
SULFISOXAZOLE DIOLAMINE;
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-;
SULFISOXAZOLE 500 MG;
SULFISOXAZOLE 600 MG;
SULFISOXAZOLE 10 %;
SULFISOXAZOLE 15 % |
- 134. 24a
- [Mandibular left central incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553662) =Medical Device =Artificial dentition;
| - 184. 4-Aminobenzenesulfonamide
- [potent antibacterial agent, the first of the sulfonamides discovered. ( CSP )] (UMLS (NCI) C0038702) =Organic Chemical; Antibiotic =Sulfanilamides;
benzenesulfonamide;
antibacterial agent;
[GU300] ANTI-INFECTIVES, VAGINAL =Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-;
SULFANILAMIDE 1.05 GM;
SULFANILAMIDE 15 %;
|
- 135. 25a
- [Mandibular right central incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553663) =Medical Device =Artificial dentition;
| - 185. 4-Aminofolic acid
- [folic acid derivative used as a rodenticide that has been shown to be teratogenic. ( CSP )] (UMLS (NCI) C0002583) =Organic Chemical; Hazardous or Poisonous Substance
|
- 136. 26a
- [Mandibular right lateral incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553664) =Medical Device =Artificial dentition;
| - 186. 4-Androstene-3,17-dione
- [delta-4 C19 steroid that is produced in the testes, ovaries and adrenal cortex and can serve as a precursor to testosterone as well as estrone and estradiol. ( CSP )] (UMLS (NCI) C0002860) =Steroid; Pharmacologic Substance; Hormone
|
- 137. 27a
- [Mandibular right canine abutment ( HL7V3.0 )] (UMLS (HL7) C1553665) =Medical Device =Artificial dentition;
| - 187. 4a
- [Maxillary right second premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553636) =Medical Device =Artificial dentition;
|
- 138. 28a
- [Mandibular right first premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553666) =Medical Device =Artificial dentition;
| - 188. 5 Alpha-Reductase Inhibitor
- [Substances that inhibit 5-alpha-Reductase, an enzyme that metabolizes testosterone to dihydrotestosterone, and can reduce prostate size. ( NCI )] (UMLS (NCI) C1318898) 5-alpha Reductase Inhibitors;
=Pharmacologic Substance ;
=enzyme inhibitor;
|
- 139. 29a
- [Mandibular right second premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553667) =Medical Device =Artificial dentition;
| - 189. 5 aminolevulinate synthase
- [An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37. ( MSH )] (UMLS (CSP) C0002565) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 140. 2a
- [Maxillary right second molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553634) =Medical Device =Artificial dentition;
| - 190. 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine Hydroxide, Inner Salt
- [physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms; possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. ( CSP )] (UMLS (NCI) C0036002) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =adenosine;
L-Methionine;
high energy compound;
|
- 141. 2alpha,3beta,23-Trihydroxyurs-12-en-28-oic Acid
- (UMLS (NCI) C0081660) =Organic Chemical; Pharmacologic Substance ;
| - 191. 5-ALA
- [A drug used in photodynamic therapy that is absorbed by tumor cells; when exposed to light, it becomes active and kills the cancer cells. ( NCI )] (UMLS (NCI) C0002563) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
|
- 142. 2alpha,3beta,6beta,23-Tetrahydroxyurs-12-en-28-oic Acid
- (UMLS (NCI) C0065501) =Organic Chemical; Pharmacologic Substance ;
| - 192. 5-Amino-2-hydroxybenzoic Acid
- [An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04) ( NCI )] (UMLS (NCI) C0127615) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=Aminosalicylic Acids;
[GA900] GASTRIC MEDICATIONS, OTHER;
[RS100] ANTI-INFLAMMATORIES, RECTAL;
=MESALAMINE 250 MG;
MESALAMINE 500 MG;
MESALAMINE 400 MG;
MESALAMINE 4 GM/60ML |
- 143. 3'-Azido-3'-deoxythymidine
- [synthetic thymidine analog that inhibits replication of some retroviruses, including human immunodeficiency virus; used in the management of AIDS or HIV infection. ( CSP )] (UMLS (NCI) C0043474) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
Dideoxynucleosides;
dT;
2'3' dideoxynucleoside =ZIDOVUDINE 100 MG;
ZIDOVUDINE 300 MG;
ZIDOVUDINE 10 MG/ML | - 193. 5-Amino-6-(70-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic Acid
- [An aminoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces flocculus. Streptonigrin complexes with DNA and topoisomerase II, resulting in DNA cleavage and inhibition of DNA replication and RNA synthesis. This agent also acts as a reverse transcriptase inhibitor and causes free radical-mediated cellular damage. (NCI04) ( NCI )] (UMLS (NCI) C0038427) =Organic Chemical; Antibiotic ;
|
- 144. 3,3'-Azobis[6-hydroxybenzoic Acid]
- [A prodrug of mesalamine (5-Aminosalicylic acid; 5-ASA) with anti-inflammatory activity. Unabsorbed olsalazine passes through gastrointestinal tract and is cleaved by azoreductases, produced by microflora in colon, into 2 active molecules of 5-ASA. 5-ASA exerts its anti-inflammatory action locally by inhibiting cyclooxygenase and lipoxygenase activities, thereby reducing the production of prostaglandins and leukotrienes. In addition, mesalamine may act as a scavenger of reactive oxygen free radicals. ( NCI )] (UMLS (NCI) C0069454) =Organic Chemical; Pharmacologic Substance ;
=Aminosalicylic Acids;
[GA900] GASTRIC MEDICATIONS, OTHER =Olsalazine Sodium;
| - 194. 5-AZA-dCyd/IDA
- (UMLS (NCI) C0279499) =Therapeutic or Preventive Procedure
|
- 145. 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m-ethylthiazolium Chloride, Monohydrochloride
- [The hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, thiamine hydrochloride is phosphorylated by thiamine diphosphokinase to form active thiamine pyrophosphate (TPP), also known as cocarboxylase. TPP is an coenzyme for many enzymatic activities involving fatty acid, amino acid and carbohydrate metabolism. ( NCI )] (UMLS (NCI) C0770309) THIAMINE HYDROCHLORIDE;
THIAMINE HYDROCHLORIDE PREPARATION;
Vitamin B1 Hydrochloride =Organic Chemical; Pharmacologic Substance; Vitamin =[VT105] THIAMINE;
=CRITICARE HN LIQUID;
LONALAC POWDER,ORAL;
MERITENE More… | - 195. 593A
- (UMLS (NCI) C0098709) =Organic Chemical; Pharmacologic Substance ;
|
- 146. 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1h-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-2-propenamide
- [A pyrrolo(1,4)benzodiazepine antineoplastic antibiotic isolated from the bacterium Streptomyces refuineus var. thermotolerans. Anthramycin binds covalently to guanine in the minor groove of DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0003167) =Organic Chemical; Antibiotic
| - 196. 5a
- [Maxillary right first premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553637) =Medical Device =Artificial dentition;
|
- 147. 3-(Aminocarbonyl)-O4-deacetyl-3-de-(methoxycarbonyl)vincaleukoblastine
- [An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. ( NCI )] (UMLS (NCI) C0042682) =Organic Chemical; Pharmacologic Substance ;
| - 197. 5a-Reductase Inhibition
- (UMLS (NCI) C0280703) =Therapeutic or Preventive Procedure
|
- 148. 3-(Aminomethyl)-5-methyl-hexanoic Acid
- [A 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic and analgesic activities. Pregabalin selectively binds to alpha2delta (A2D) subunit of the presynaptic voltage-gated calcium channels located in the central nervous system (CNS). Binding of A2D subunits prevent calcium influxes and the subsequent calcium-dependent releases of various neurotransmitters from presynaptic nerve terminals in hyperexcited neurons, including glutamate, norepinephrine, serotonin, dopamine, and substance P. This leads to an inhibition of synaptic transmission and reduces neuronal excitability. Pregabalin does not bind directly to GABA-A, GABA-B receptors and does not alter GABA uptake or degradation. ( NCI )] (UMLS (NCI) C0657912) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 198. 5alpha,7alpha(S))-alpha-tert-Butyl-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol Hydrochloride
- [The hydrochloride salt form of buprenorphine, a synthetic phenanthrene with narcotic analgesic activity. Buprenorphine hydrochloride is a partial agonist at the mu-opioid receptor and an antagonist at the kapa-opioid receptor in the central nervous system. However, under the conditions of recommended use it behaves as a classic mu-opioid agonist, mimicking the actions of endogenous peptides at CNS opioid receptors. The agonist action results in a raised pain threshold and increased tolerance to pain. However, it also causes sedation, physical dependence, and respiratory depressant effects and decreases heart rate and blood pressure. ( NCI )] (UMLS (NCI) C0701445) =Organic Chemical; Pharmacologic Substance ;
=buprenorphine;
=BUPRENORPHINE HYDROCHLORIDE 0.3 MG/ML;
BUPRENORPHINE HYDROCHLORIDE 2 MG;
BUPRENORPHINE HYDROCHLORIDE 8 MG |
- 149. 3-ABaP
- [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 3-aminobenzo(a)pyrene consists of five fused rings with an amino-group attached to the third carbon atom of the aromatic hydrocarbon ring with potential carcinogenicity. ( NCI )] (UMLS (NCI) C0768968) 3-Aminobenzo[a]pyrene;
=Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance | - 199. 5alphaR
- [ ] (UMLS (CSP) C0599937) =Amino Acid, Peptide, or Protein; Enzyme
|
- 150. 3-Amino-1,2,4-benzotriazine-1,4-dioxide
- [antineoplastic, radiation sensitizing agent; 3-amino1,2,4-benzotriazine 1,4-dioxide. ( CSP )] (UMLS (NCI) C0208407) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Radiation Sensitizers;
triazine;
| - 200. 6 aminonicotinamide
- [A synthetic analogue and nicotinamide antagonist with cytotoxic properties, 6-Aminonicotinamide forms an abnormal NAD (ubiquitous metabolic pathway coenzyme) analog that inhibits NAD-dependent enzyme activity associated with ATP production. 6-Aminonicotinamide impairs cartilage formation, may have teratogenic effects, and enhances the effect of radiation and cisplatin treatment (formation of platinum-DNA complexes). (NCI04) ( NCI )] (UMLS (CSP) C0000610) =Organic Chemical; Pharmacologic Substance; Vitamin; Hazardous or Poisonous Substance
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