 | Medical glossary. |
| selected terms: 11,457 | page 1 of 573 |
- (+)-2-Ethoxy-alpha-(((S)-alpha-isobutyl-o-piperidinobenzyl)carbamoyl)-p-toluic Acid
- [A benzoic acid derivative belonging to the meglitinide class of antidiabetic agents. Repaglinide blocks ATP-dependent potassium channels in pancreatic beta cells, thereby causing depolarization of the cell membrane and subsequent opening of calcium channels. The increased calcium influx into the pancreatic beta cells induces insulin secretion, thereby lowering blood glucose levels. ( NCI )] (UMLS (NCI) C0246689) =Organic Chemical; Pharmacologic Substance ;; More…
- (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride
- [The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. ( NCI )] (UMLS (NCI) C0770927) Lomefloxacin Hydrochloride;;LOMEFLOXACIN More…
- (+-)-4'-(4-(Ethylheptylamino)-1-hydroxybutyl)methanesulfonanilide Fumarate(2:1)(salt)
- [The fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval. (NCI05) ( NCI )] (UMLS (NCI) More…
- (+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one
- [A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04) ( NCI )] (UMLS (NCI) C0028368) =Steroid; More…
- (-)-Ephedrine
- [alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine; has been used in the treatment of several disorders including asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. ( CSP )] (UMLS (NCI) C0014479) =Organic Chemical; Pharmacologic Substance ;; =adrenergic agent;;bronchodilator;;Phenethylamines;;Propanolamines;;[AU100] SYMPATHOMIMETICS More…
- (-)-Epigallocatechin 3-gallate
- [A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. It is under study as a potential cancer chemopreventive agent. (NCI) ( NCI )] (UMLS (NCI) C0059438) =Organic Chemical; Pharmacologic Substance ;;
- (-)-Epothilone B
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called epothilones. Also called EPO906. ( NCI )] (UMLS (NCI) C0297960) =Organic Chemical; Pharmacologic Substance
- (161-180)ESO-1
- [A recombinant 19-residue peptide vaccine consisting of amino acids 161 through 180 of the cancer/testis (CT) antigen. ESO-1 (161-180) peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for ESO-1, resulting in decreased tumor growth. ESO-1 is expressed in a variety of cancers, including melanoma, breast, bladder, prostate, and hepatocellular cancers. (NCI04) ( NCI )] (UMLS (NCI) C1520653) ESO-1 (161-180) More…
- (2E)-5-[3-[(Phenylsufonyl) Aminol Phenyl]-pent-2-en-4-ynohydroxamic Acid
- [An inhibitor of histone deacetylase. It is an aromatic sulfonamide hydroxamate initially found in a screen for inhibitors of the tumorigenic phenotype of K-ras-transformed NIH3T3 cells. ( NCI )] (UMLS (NCI) C0391491) =Organic Chemical; Pharmacologic Substance ;;
- (2E,4E,6E)-7-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-methyl-2,4,6-octatrienoic Acid
- (UMLS (NCI) C1708619) =Organic Chemical; Pharmacologic Substance
- (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid, Ethyl Ester
- [A synthetic oral retinoid that is a prodrug of acitretin. Etretinate activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. Etretinate is no longer commercially available in the U.S. due to the extended potential for teratogenic effects related to its long half-life. (NCI04) ( NCI )] (UMLS (NCI) C0015137) =Organic Chemical; Pharmacologic Substance ;; =Retinoic Acid More…
- (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
- [A natural derivative of dienohydroxamic acid isolated from species of the bacterial genus Streptomyces. Trichostatin A (TSA) reversibly and specifically inhibits histone deacetylases, resulting in hyperacetylation of core histones which modulate chromatin structure. The increase in histone acetylation promotes selective gene transcription and the inhibition of tumor growth. This agent is a potent inducer of tumor cell growth arrest, differentiation and apoptosis in a variety of More…
- (9E)-Erythromycin, 9-[O-[(2-methoxyethoxy)methyl]oxime]
- [Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections. ( MSH )] (UMLS (NCI) C0035891) =Organic Chemical; Antibiotic ;;
- (E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup 2(1H),delta)-pentalenevaleric Acid
- [specific isomer of hexahydro-5-hydroxy-4- (3-hydroxy-4-methyl-1- octen-6-ynyl) pentalenevaleric acid; prostacyclin analog and agonist; has vasodilator and anticoagulant actions and therefore may be useful for treating a variety of vascular disorders. ( CSP )] (UMLS (NCI) C0079594) =Eicosanoid; Pharmacologic Substance =prostaglandin analog;;
- (E)--1-[4'-(2-dimethylaminoethyoxy)phenyl]-1(3-hydroxyphenyl)-2-phenyl-but-1-ene
- [A phenolic analogue of tamoxifen, a nonsteroidal selective estrogen receptor modulator (SERM). Droloxifene competitively inhibits the binding of estradiol to estrogen receptors, thereby preventing the receptor from binding to the estrogen-response element on DNA. The result is a reduction in DNA synthesis and cellular response to estrogen. (NCI) ( NCI )] (UMLS (NCI) C0047498) =Organic Chemical; Pharmacologic Substance ;;
- (E)-2-Butenedioic Acid
- (UMLS (NCI) C0060825) =Organic Chemical; Pharmacologic Substance ;; =fumarate;;Inactive Ingredient Preparations =AL OH 400MG/MG OH 400MG/SIMETHICONE 30MG TAB,CHEWABLE;;
- (E)-2-Butenedioic Acid, Dimethyl Ester
- (UMLS (NCI) C0058218) =Organic Chemical; Pharmacologic Substance ;;
- (E)-2-Butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic Acid, Monomethanesulfonate
- [The mesylate salt form of eprosartan, a non-biphenyl, non-tetrazole, nonpeptide angiotensin II antagonist with antihypertensive activity. Eprosartan mesylate antagonizes angiotensin II type I receptors in tissues such as vascular smooth muscle and the adrenal gland. This prevents angiotensin II-induced vasoconstriction and prevents angiotensin II-mediated stimulation of aldosterone secretion by the adrenal cortex, which decreases the excretion of sodium and water and increases the More…
- (E)-3,7-Dimethyl-2,6-octadien-1-ol
- (UMLS (NCI) C0061223) =Organic Chemical; Pharmacologic Substance ;;
- (E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol
- [synthetic nonsteroidal estrogen used in the treatment of menopausal, postmenopausal, and other disorders sensitive to estrogens; an epigenetic carcinogen. ( CSP )] (UMLS (NCI) C0012203) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =female antifertility drug;;[HS300] ESTROGENS;;estrogen analog;;stilbene;;Teratogen;; =(E)-4,4'-(1,2-ethenediyl)-bisphenol bis(dihydrogen phosphate);;DIETHYLSTILBESTROL 1 MG;;DIETHYLSTILBESTROL 5 MG;;
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