UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
R R R- R0 R1 R2 R3 R4 RA RB RC RD RE RF RG RH RI RK RM RN RO RP RQ RR RS RT RU RV RW RX RY
RB1 RBB RBC RBD RBE RBG RBI RBL RBM RBX

(-)-(R)-1-(4,4-Bis(3-methyl-2-thienyl)-3-butenyl)nipecotic Acid, Hydrochloride

[The hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. Tiagabine hydrochloride inhibits the gamma-aminobutyric acid (GABA) transporter type 1 (GAT1), which is predominantly localized in presynaptic terminals of neurons thereby preventing the reuptake of GABA by the presynaptic endings. Consequently, this increases the level of available GABA within the synaptic cleft, thereby resulting in prolongation of its inhibitory actions. Tiagabine is effective against maximum electroshock seizures and both limbic and generalized tonic-clonic seizures. ( NCI )]
UMLS (NCI) C0772200
3-Piperidinecarboxylic Acid, 1-(4,4-bis(3-methyl-2-thienyl)-3-buten-yl)-, Hydrochloride,(R)-
Tiagabine Hydrochloride
TIAGABINE HYDROCHLORIDE PREPARATION
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: TIAGABINE
Relation/CHD: TIAGABINE HYDROCHLORIDE 12 MG
TIAGABINE HYDROCHLORIDE 16 MG
TIAGABINE HYDROCHLORIDE 4 MG
TIAGABINE HYDROCHLORIDE 2 MG

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