UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
B B B0 B1 B4 B7 B8 BA BB BC BD BE BF BG BH BI BK BL BM BN BO BP BR BS BT BU BV BW BX BY BZ
BE BE+ BEA BEB BEC BED BEE BEF BEG BEH BEI BEK BEL BEM BEN BEP BER BES BET BEU BEV BEX

(11beta,16alpha)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

[The furoate salt form of mometasone, a synthetic topical glucocorticosteroid receptor agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Mometasone furoate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.. Specifically, mometasone furoate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2. ( NCI )]
UMLS (NCI) C0066700
 
Steroid
Pharmacologic Substance
Relation/PAR: Pregnadienediols
MOMETASONE
Relation/CHD: MOMETASONE FUROATE 0.1 %

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