[The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation. Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors. This opioid exerts its analgesic actions primarily through kappa-opioid-receptor agonism and partially through mu-opioid receptor agonism. ( NCI )]
UMLS (NCI) C0600099 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: NALBUPHINE
Relation/CHD: NALBUPHINE HYDROCHLORIDE 20 MG/ML
NALBUPHINE HYDROCHLORIDE 1.5 MG/ML
NALBUPHINE HYDROCHLORIDE 10 MG/ML