A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
(All-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid
[A naturally-occurring acid of retinol. Tretinoin binds to and activates retinoic acid receptors (RARs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, and inhibition of tumorigenesis. This agent also inhibits telomerase, resulting in telomere shortening and eventual apoptosis of some tumor cell types. The oral form of tretinoin has teratogenic and embryotoxic properties. ( NCI )]
UMLS (NCI) C0040845- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [AN000] ANTINEOPLASTICS
[VT050] VITAMIN A
[DE752] ANTIACNE AGENTS, TOPICAL
[VT050] VITAMIN A
[DE752] ANTIACNE AGENTS, TOPICAL
Relation/CHD: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid
TRETINOIN 10 MG
TRETINOIN PWDR
TRETINOIN 0.05 %
TRETINOIN 0.1 %
TRETINOIN 0.01 %
TRETINOIN 0.025 %
TRETINOIN 0.04 %
TRETINOIN 10 MG
TRETINOIN PWDR
TRETINOIN 0.05 %
TRETINOIN 0.1 %
TRETINOIN 0.01 %
TRETINOIN 0.025 %
TRETINOIN 0.04 %
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