UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
H H+ H1 HA HB HC HD HE HF HG HH HI HK HL HM HN HO HP HQ HR HS HT HU HV HX HY HZ
HEA HEB HEC HED HEE HEF HEI HEL HEM HEN HEP HER HES HET HEU HEV HEX HEY

1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane

[A fluorinated isopropyl ether with general anesthetic property. Although the mechanism of action has not been fully elucidated, sevoflurane may act by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, and/or alter ionic conductance following receptor activation by a neurotransmitter. Sevoflurane may also interact directly with lipid matrix of neuronal membranes, thereby affecting gating properties of ion channels. In addition, this agent may activate gamma-aminobutyric acid (GABA) receptors hyperpolarizing cell membranes. This results in a general anesthetic effect, a decrease in myocardial contractility and mean arterial pressure as well as an increased respiratory rate. ( NCI )]
UMLS (NCI) C0074414
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: Methyl Ethers
[CN201] ANESTHETICS INHALATION
Relation/CHD: SEVOFLURANE LIQUID (ML)

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