1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone
[An azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with cholesterol transporters at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol and related phytosterols. As a result, ezetimibe causes a decrease in the level of blood cholesterol or an increase in the clearance of cholesterol from the bloodstream. Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, LDL cholesterol, and other triglycerides in the blood. ( NCI )]
UMLS (NCI) C1142985EZETIMIBE
EZETIMIBE PREPARATION
EZETIMIBE PREPARATION
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [CV350] ANTILIPEMIC AGENTS
Unclassified Ingredients
Unclassified Ingredients
Relation/CHD: EZETIMIBE 10 MG
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