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1-amino-3,5-dimethyladamantane Hydrochloride
[The hydrochloride salt form of memantine, a moderate affinity, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine hydrochloride exerts its effect by binding to the cation channels on the NMDA receptor located in the central nervous system, thereby blocking the NMDA receptor and preventing the binding of the excitatory amino acid glutamate. This results in a reduction of abnormal excitement in the brain, which is often seen in Alzheimer's disease. Memantine hydrochloride also acts as an antagonist at the 5HT 3 receptor and the nicotinic receptor. ( NCI )]
UMLS (NCI) C0771988Ebixia
MEMANTINE HYDROCHLORIDE
MEMANTINE HYDROCHLORIDE
- Organic Chemical
- Pharmacologic Substance
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