UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
B B B0 B1 B4 B7 B8 BA BB BC BD BE BF BG BH BI BK BL BM BN BO BP BR BS BT BU BV BW BX BY BZ
BE BE+ BEA BEB BEC BED BEE BEF BEG BEH BEI BEK BEL BEM BEN BEP BER BES BET BEU BEV BEX

1-beta-D-Ribofuranosyl-2(1H)-pyrimidinone

[A synthetic cytidine analogue and a cytidine deaminase inhibitor with anticancer activity. Following metabolic activation by phosphorylation and incorporation into DNA, zebularine inhibits DNA methyltransferase through covalent complex formation between the enzyme and zebularine-substituted DNA, hence resulting in non-specific, genome-wide induction of demethylation including the removal of aberrant methylation of promoter regions of genes critical for normal cellular functions. ( NCI )]
UMLS (NCI) C0084253
 
Nucleic Acid, Nucleoside, or Nucleotide
Pharmacologic Substance

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