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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
C C- C1 C3 C5 C6 C7 CA CB CC CD CE CF CG CH CI CJ CK CL CM CN CO CP CQ CR CS CT CU CV CW CX CY CZ
CY CY CYA CYB CYC CYE CYF CYK CYL CYM CYP CYS CYT

2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid

[A synthetic, triterpenoid compound with anticancer and anti-inflammatory activities. CDDO blocks the synthesis of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2), two enzymes involved in inflammation and carcinogenesis. This agent also inhibits the interleukin-1 (IL-1)-induced expression of the pro-inflammatory proteins matrix metalloproteinase-1 (MMP-1) and matrix metalloproteinase-13 (MMP-13) and the expression of Bcl-3, an IL-1-responsive gene that preferentially contributes to MMP-1 gene expression. ( NCI )]
UMLS (NCI) C0762434
2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid
CDDO
 
Organic Chemical
Pharmacologic Substance

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