[A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05) ( NCI )]
UMLS (NCI) C0018513 - Steroid
- Pharmacologic Substance
Relation/PAR: Pregnenediones
[DE200] ANTI-INFLAMMATORY, TOPICAL
Relation/CHD: HALCINONIDE 0.025 %
HALCINONIDE 0.1 %