2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-
[A synthetic benzodiazepine derivative with anxiolytic, sedative and hypnotic properties. Quazepam and its major metabolite 2-oxoquazepam potentiate gamma-aminobutyric acid (GABA) activity by binding to the benzodiazepine-1 recognition site (BZ-1) within the GABA-A receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of GABA-activated chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreased neuronal excitability. ( NCI )]
UMLS (NCI) C0072828- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS
Unclassified Ingredients
Unclassified Ingredients
Relation/CHD: QUAZEPAM 15 MG
QUAZEPAM 7.5 MG
QUAZEPAM 7.5 MG
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