2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-
[A benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone also inhibits the synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors. ( NCI )]
UMLS (NCI) C0380393- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Piperazines
thiazole
[CN709] ANTIPSYCHOTICS, OTHER
thiazole
[CN709] ANTIPSYCHOTICS, OTHER
Relation/CHD: ZIPRASIDONE 20 MG
ZIPRASIDONE 40 MG
ZIPRASIDONE 60 MG
ZIPRASIDONE 80 MG
ZIPRASIDONE 40 MG
ZIPRASIDONE 60 MG
ZIPRASIDONE 80 MG
Buy website
Medical Clinic. Optician. Pharmacy. Physician. Travel Agency. Hotel reservation. Child Care. Education. Teachers. Lessons. Tests and Exams. Certification. Shopping Center. Store. Real Estate.Affordable prices from $100.
  |
home
