3-Hydroxy-alpha-methyl-L-tyrosine
[A phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure. ( NCI )]
UMLS (NCI) C0025741- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Neuroreactive Substance or Biogenic Amine
Relation/PAR: dihydroxyphenylalanine
[CV490] ANTIHYPERTENSIVES, OTHER
[CV490] ANTIHYPERTENSIVES, OTHER
Relation/CHD: (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic Acid
METHYLDOPATE
METHYLDOPA 250 MG
METHYLDOPA 125 MG
METHYLDOPA 500 MG
METHYLDOPATE
METHYLDOPA 250 MG
METHYLDOPA 125 MG
METHYLDOPA 500 MG
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