4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide

[A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death. ( NCI )]

UMLS (NCI) C0038745

Organic Chemical
Pharmacologic Substance

Relation/PAR: Sulfanilamides
[AM650] SULFONAMIDE/RELATED ANTIMICROBIALS

Relation/CHD: SULFISOXAZOLE DIOLAMINE
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-
SULFISOXAZOLE DIOLAMINE
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-
SULFISOXAZOLE 500 MG
SULFISOXAZOLE 600 MG
SULFISOXAZOLE 10 %
SULFISOXAZOLE 15 %

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