4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic Acid
[A sialic acid analog and a neuraminidase inhibitor with antiviral property. Zanamivir selectively inhibits influenza A and B virus neuraminidase, a viral surface glycoprotein, which mediates the cleavages of sialic acid residues on the surfaces of host cells and influenza viral envelopes. The uncleaved sialic acid residues were bound by viral hemagglutinin, thereby resulting in viral aggregation at the host cell surface, thereby preventing the release of influenza virus particles into the respiratory tract. ( NCI )]
UMLS (NCI) C0216660- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [AM800] ANTIVIRALS
Sialic Acids
Sialic Acids
Relation/CHD: ZANAMIVIR 5 MG
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