A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
5alpha,7alpha(S))-alpha-tert-Butyl-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol Hydrochloride
[The hydrochloride salt form of buprenorphine, a synthetic phenanthrene with narcotic analgesic activity. Buprenorphine hydrochloride is a partial agonist at the mu-opioid receptor and an antagonist at the kapa-opioid receptor in the central nervous system. However, under the conditions of recommended use it behaves as a classic mu-opioid agonist, mimicking the actions of endogenous peptides at CNS opioid receptors. The agonist action results in a raised pain threshold and increased tolerance to pain. However, it also causes sedation, physical dependence, and respiratory depressant effects and decreases heart rate and blood pressure. ( NCI )]
UMLS (NCI) C0701445- Organic Chemical
- Pharmacologic Substance
Relation/PAR: buprenorphine
Relation/CHD: BUPRENORPHINE HYDROCHLORIDE 0.3 MG/ML
BUPRENORPHINE HYDROCHLORIDE 2 MG
BUPRENORPHINE HYDROCHLORIDE 8 MG
BUPRENORPHINE HYDROCHLORIDE 2 MG
BUPRENORPHINE HYDROCHLORIDE 8 MG
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