A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
ABD-B
[Encoded by human HOXA9 Gene (ABD-B Family), 272-amino acid 30-kD Homeobox Protein A9 isoforms are class I sequence-specific DNA-binding homeobox transcription factors potentially involved in morphogenesis and myeloid differentiation; expression is spatially and temporally regulated during embryonic development. Frameshifted isoform B contains a distinct C-terminus lacking the homeodomain. HOXA9 acts within a developmental regulatory system that provides specific anterior-posterior positional identity to cells. Associated with acute myeloid leukemogenesis, a chimerically fused in-frame nucleoporin NUP98 amino terminal half to HOXA9 may inhibit differentiation or disrupt nucleocytoplasmic transport. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C0386322- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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