A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AF-1
[Encoded by human IFNGR2 Gene (Type II Cytokine Receptor Family), 337-aa 38-kDa (precursor) type I membrane protein Interferon Gamma Receptor Beta Chain is an integral accessory factor subunit of Interferon Gamma Receptor Complex required for signal transduction. Ser/Thr phosphorylated IFN Gamma Receptor activates macrophages in innate immune responses to viral infection and host defenses. Ligand-bound receptor activates JAK kinases leading to tyrosine phosphorylation of STAT1 and STAT2. IFNGR1 constitutes the receptor ligand-binding alpha chain. Containing 2 fibronectin type III domains, IFNGR2 may interact with GAF, JAK1, and/or JAK2. (NCI) ( NCI )]
UMLS (NCI) C1334196IFGR2
Interferon Gamma Receptor Accessory Factor-1
Interferon Gamma Receptor Beta Chain
Interferon Gamma Receptor-2
Interferon Gamma Transducer-1
Interferon Gamma Receptor Accessory Factor-1
Interferon Gamma Receptor Beta Chain
Interferon Gamma Receptor-2
Interferon Gamma Transducer-1
- Amino Acid, Peptide, or Protein
- Receptor
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