[Baculoviral IAP Repeat-Containing Protein 6, encoded by the BIRC6 gene, is a member of the IAP (inhibitors of apoptosis proteins) family and the ubiquitin-conjugating enzyme family. This protein is expressed as a 530-kD protein in gliomas and ovarian cancers. BIRC6 may protect cancer cells from undergoing apoptosis and resist to apoptosis in the presence of anticancer drugs. BIRC6 contains a 70-amino acid cysteine- and histidine-rich baculovirus IAP repeat (BIR) and a zinc-binding RING finger. ( NCI )]
UMLS (NCI) C0910612Baculoviral IAP Repeat-Containing Protein 6
BIRC6
KIAA1289
- Amino Acid, Peptide, or Protein
- Biologically Active Substance