B1
[Expressed during B-cell ontogeny (early pre-B-cell to plasma cell) by human CD20 Gene (MS4A Family), 297-aa 33-kDa CD20 Antigen is a phosphorylated cell surface integral membrane protein shown to participate in B-cell proliferation, development, and differentiation into plasma cells. MS4A family proteins share structural similarity, sequence homology, and unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A proteins contain 4 highly conserved transmembrane domains, flanked by N- and C-terminal cytoplasmic regions. CD20 may be involved in regulation of B-cell activation and may be regulated by protein kinases. (NCI) ( NCI )]
UMLS (NCI) C0054946- Amino Acid, Peptide, or Protein
- Immunologic Factor
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