[Thy hydrochloride salt of a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril hydrochloride is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Benazepril hydrochloride also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. ( NCI )]
UMLS (NCI) C0770917Benazepril Hydrochloride
BENAZEPRIL HYDROCHLORIDE PREPARATION
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: benazepril
Relation/CHD: BENAZEPRIL HYDROCHLORIDE 20 MG
BENAZEPRIL HYDROCHLORIDE 40 MG
BENAZEPRIL HYDROCHLORIDE 5 MG
BENAZEPRIL HYDROCHLORIDE 10 MG