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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
C C- C1 C3 C5 C6 C7 CA CB CC CD CE CF CG CH CI CJ CK CL CM CN CO CP CQ CR CS CT CU CV CW CX CY CZ
CC CC- CC4 CC5 CCA CCB CCC CCD CCE CCF CCG CCH CCI CCK CCL CCM CCN CCQ CCR CCS

C-C Chemokine Receptor Type 5

[Chemokine (C-C Motif) Receptor 5, encoded by the CCR5 gene, is a member of the beta chemokine receptor family and a seven transmembrane protein similar to G protein-coupled receptor. This receptor is expressed by T cells and macrophages, and is an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene is associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene is also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. (From LocusLink and NCI) ( NCI )]
UMLS (NCI) C0387687
 
Amino Acid, Peptide, or Protein
Immunologic Factor
Receptor

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