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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
E E0 E6 E7 EA EB EC ED EE EF EG EH EI EJ EK EL EM EN EO EP EQ ER ES ET EU EV EW EX EY
EFA EFF EFH EFL EFO EFP EFT EFU

E-F1

[Heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma or alpha/delta/gamma subunits) is responsible for delivery of aminoacyl tRNAs to the ribosome. Containing domains that bind guanine nucleotides, 80S ribosomes, and aminoacyl-tRNAs, the alpha EF-1 subunit interacts with beta/delta subunits and mediates delivery and GTP-dependent binding of aminoacyl-tRNAs to the 80S ribosome A-site. Homologous beta and delta subunits (guanine nucleotide exchange factors) stimulate GDP/GTP exchange bound to EF-1-alpha; phosphorylation affects the GDP/GTP exchange rate. The conserved gamma subunit contains an EEF1G domain and an N-terminal GST domain that may be involved in regulating EF-1 multisubunit assembly and anchorage to other cellular components. (NCI) ( NCI )]
UMLS (NCI) C0059036
 
Amino Acid, Peptide, or Protein
Enzyme

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