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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
E E0 E6 E7 EA EB EC ED EE EF EG EH EI EJ EK EL EM EN EO EP EQ ER ES ET EU EV EW EX EY
ER ER+ ER- ERA ERB ERC ERD ERE ERF ERG ERI ERK ERL ERO ERP ERR ERS ERT ERU ERY

ERK 2

[Encoded by Human MAPK1 Gene (MAPK Family) as alternative p40 and p41 isoforms, Mitogen-Activated Protein Kinase 1 is a proline-directed Ser/Thr kinase activated in response to extracellular stimuli and widely involved in signal transduction as an integration point for multiple biochemical signals and as part of complex protein kinase cascades involved in a cell proliferation, differentiation, transcription regulation, and development. Autophosphorylated and phosphorylated/activated by upstream kinases on threonine and tyrosine residues, MAPK1 forms dimers with phosphorylated and unphosphorylated ERK partners, translocates to the nucleus and phosphorylates target transcription factors. MAPK1 phosphorylates MAP2, MBP, and ELK-1. (NCI) ( NCI )]
UMLS (CSP) C0170168
 
Amino Acid, Peptide, or Protein
Enzyme

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