Edetate Disodium

[The disodium salt form of edetate, a heavy metal chelating agent with anti-hypercalcemic and anti-arrhythmic properties. Edetate, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes which are readily excreted by the kidneys, thereby can be used to lower serum calcium concentrations. In addition, this agent exerts a negative inotropic effect on the heart through a transiently induced hypocalcemic state, thereby antagonizing the inotropic and chronotropic effects of digitalis glycosides on the ventricles of the heart. Upon ocular administration, edetate exerts its ophthalmic effect by chelating calcium to form soluble complexes, thereby removing corneal calcium deposits. ( NCI )]

UMLS (NCI) C0012695

Organic Chemical
Pharmacologic Substance
Indicator, Reagent, or Diagnostic Aid

Relation/PAR: EDETATE

Relation/CHD: MASSENGILL DISPOSABLE DOUCHE
Calcium Carbonate 500 MG / Vitamin D 200 UNT Oral Tablet [Os Cal 500 with D]
Naphazoline 0.5 MG/ML Nasal Solution
xylometazoline 0.5 MG/ML Nasal Solution
Cetylpyridinium 0.5 MG/ML Mouthwash
CONTACT LENS (FOR HARD LENS) SOLN
CONTACT LENS SOAKING SOLN
CONTACT LENS WET & SOAK SOLN
CONTACT LENS WETTING SOLN
ENZYMATIC CLEANER (PAPAIN) TAB,OPH
EXTRA STRENGTH HAND & NAIL LOTION
MASSENGILL DISPOSABLE DOUCHE BELLE-MAI,VAG
Metronidazole 0.0075 MG/MG Topical Gel
OCUCLENZ OPH,IRRG
OPTIGENE EYE WASH
PERNOX SHAMPOO
PROGAINE NORMAL TO DRY SHAMPOO
PROGAINE NORMAL TO OILY SHAMPOO
Salicylic Acid & Sulfur Liquid Soap 2-2%
SULFUR 5% SHAMPOO
ULTRA-KLENZ,WOUND CLEANSER
MASSENGILL DOUCHE,VAG
EDETATE DISODIUM 0.2 MG/ML
EDETATE DISODIUM 0.25 MG/ML
EDETATE DISODIUM 0.3 GM
EDETATE DISODIUM 0.4 MG
EDETATE DISODIUM 01 %
EDETATE DISODIUM 150 MG/ML

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