Etoposide Phosphate
[A phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks, inhibiting DNA repair, and resulting in decreased DNA synthesis and tumor cell proliferation. Cells in the S and G2 phases of the cell cycle are most sensitive to this agent. (NCI04) ( NCI )]
UMLS (NCI) C0059874- Organic Chemical
- Pharmacologic Substance
Relation/PAR: 4'-Demethylepipodophyllotoxin 9-[4,6-O-ethylidene-beta-D-glucopyranoside
Organophosphorus Compounds
Organophosphorus Compounds
Relation/CHD: ETOPOSIDE PHOSPHATE 100 MG
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