[Encoded by human GNB3 Gene, 340-aa 37-kDa Guanine Nucleotide Binding Protein Beta 3 is a heterotrimeric G protein beta subunit with 7 WD repeats and involved in transmembrane signaling as a transducer that regulates G protein alpha subunits and integrates signals between receptors and effector proteins. The G protein beta and gamma subunits are required for GTPase activity, for GTP replacement of GDP, and for G protein/effector interaction. A splicing polymorphism is associated with essential hypertension and obesity. ( NCI )]
UMLS (NCI) C1122941GNB3
GTP-Binding Regulatory Protein Beta-3 Chain
Guanine Nucleotide Binding Protein Beta 3
Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3
Transducin Beta Chain 3
- Amino Acid, Peptide, or Protein
- Biologically Active Substance