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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
G G0 G1 G2 G3 G4 GA GB GC GD GE GF GG GH GI GL GM GN GO GP GQ GR GS GT GU GV GW GX GY GZ G%
GD GDF GDN GDP GDT

GDF15

[Expressed in activated, but not resting, macrophages and in placenta, prostate, colon, and kidney by human PLAB Gene (BMP/TGF-Beta Family), 308-aa 34-kDa (precursor) Placental TGF-Beta is processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in a disulfide-linked homodimeric secreted mature protein of 224 amino acids. PLAB regulates tissue differentiation and maintenance and reduces the growth of granulocytes and macrophages. Unlike most TGFB superfamily members, in which the amino acid sequence is completely conserved, PLAB shares only 70% amino acid identity with its rodent counterparts. (NCI) ( NCI )]
UMLS (NCI) C0668195
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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