[Human insulin-like growth factor-1 receptor protein (1367 aa, 155 kDa precursor) is encoded by the human insulin-like growth factor-1 (IGFR1) gene. This membrane-bound protein, a disulfide-linked alpha2/beta2 tetramer, binds both insulin growth factors I and II. Ligand binding activates protein kinase activity, controls cell cycle progression and enhances cell survival. ( NCI )]
UMLS (NCI) C0140080 - Amino Acid, Peptide, or Protein
- Enzyme
- Receptor