JTK14
[Specifically expressed in developing endothelial cells by human TIE Gene (TIE Tyr Kinase Family), 1138-aa 125-kDa (precursor) type I transmembrane Protein Receptor Tyrosine Kinase TIE 1 contains 2 Ig-like C2-type domains, 3 fibronectin type III domains, and 3 EGF-like domains. TIE1 receptor may be involved in multiple protein-protein interactions, possibly including endothelial cell adhesion, blood clotting, and inflammation. TIE1 receptor is important in angiogenesis, particularly endothelial vascular formation. Combinatorial ANG-1 and TIE1 orphan receptor function is critical for right-side venous system development. (NCI) ( NCI )]
UMLS (NCI) C1335549Protein Receptor Tyrosine Kinase TIE 1
TIE1
Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains
Tyrosine-Protein Kinase Receptor TIE1
TIE1
Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains
Tyrosine-Protein Kinase Receptor TIE1
- Amino Acid, Peptide, or Protein
- Enzyme
- Receptor
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